William W. Newcomb

Overview

Best Publications

• Structures of bovine and human papillomaviruses. Analysis by cryoelectron microscopy and three-dimensional image reconstruction.

  T.S. Baker;W.W. Newcomb;N.H. Olson;L.M. Cowsert

  590
  Citations

• The UL6 Gene Product Forms the Portal for Entry of DNA into the Herpes Simplex Virus Capsid

  William W. Newcomb;Rachel M. Juhas;Darrell R. Thomsen;Fred L. Homa

  432
  Citations

• Liquid-crystalline, phage-like packing of encapsidated DNA in herpes simplex virus.

  F.P. Booy;W.W. Newcomb;B.L. Trus;J.C. Brown

  372
  Citations

• Structure of the herpes simplex virus capsid : molecular composition of the pentons and the triplexes

  William W. Newcomb;Benes L. Trus;Frank P. Booy;Alasdair C. Steven

  352
  Citations

• Assembly of the herpes simplex virus capsid: characterization of intermediates observed during cell-free capsid formation.

  William W. Newcomb;Fred L. Homa;Darrell R. Thomsen;Frank P. Booy

  330
  Citations

• The herpes simplex virus procapsid: structure, conformational changes upon maturation, and roles of the triplex proteins VP19c and VP23 in assembly.

  Benes L. Trus;Frank P. Booy;William W. Newcomb;Jay C. Brown

  300
  Citations

• The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth.

  M Gao;L Matusick-Kumar;W Hurlburt;S F DiTusa

  281
  Citations

• Mass and molecular composition of vesicular stomatitis virus: a scanning transmission electron microscopy analysis.

  D Thomas;W W Newcomb;J C Brown;J S Wall

  280
  Citations

• The Product of the Herpes Simplex Virus Type 1 UL25 Gene Is Required for Encapsidation but Not for Cleavage of Replicated Viral DNA

  Alistair R. McNab;Prashant Desai;Stan Person;Lori L. Roof

  232
  Citations

• Structure and Polymorphism of the UL6 Portal Protein of Herpes Simplex Virus Type 1

  Benes L. Trus;Naiqian Cheng;William W. Newcomb;Fred L. Homa

  221
  Citations

• Herpesvirus capsid assembly: insights from structural analysis.

  Jay C Brown;William W Newcomb

  219
  Citations

• Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy.

  J. Bernard Heymann;Naiqian Cheng;William W. Newcomb;Benes L. Trus;Benes L. Trus

  215
  Citations

• Structure of the herpes simplex virus capsid: effects of extraction with guanidine hydrochloride and partial reconstitution of extracted capsids.

  W W Newcomb;J C Brown

  214
  Citations

• Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment

  Anna Maria Copeland;William W. Newcomb;Jay C. Brown

  214
  Citations

• Allosteric Signaling and a Nuclear Exit Strategy: Binding of UL25/UL17 Heterodimers to DNA-Filled HSV-1 Capsids

  Benes L. Trus;William W. Newcomb;Naiqian Cheng;Giovanni Cardone

  195
  Citations

• Assembly of the Herpes Simplex Virus Procapsid from Purified Components and Identification of Small Complexes Containing the Major Capsid and Scaffolding Proteins

  William W. Newcomb;Fred L. Homa;Darrell R. Thomsen;Benes L. Trus

  179
  Citations

• Herpes Simplex Virus DNA Cleavage and Packaging Proteins Associate with the Procapsid prior to Its Maturation

  Amy K. Sheaffer;William W. Newcomb;Min Gao;Dong Yu

  174
  Citations

• Conserved Features in Papillomavirus and Polyomavirus Capsids

  David M. Belnap;Norman H. Olson;Norman H. Olson;Norman H. Olson;Nancy M. Cladel;Nancy M. Cladel;Nancy M. Cladel;William W. Newcomb;William W. Newcomb;William W. Newcomb

  171
  Citations

• Isolation of Herpes Simplex Virus Procapsids from Cells Infected with a Protease-Deficient Mutant Virus

  William W. Newcomb;Benes L. Trus;Naiqian Cheng;Alasdair C. Steven

  169
  Citations

• Finding a needle in a haystack: detection of a small protein (the 12-kDa VP26) in a large complex (the 200-MDa capsid of herpes simplex virus).

  F P Booy;B L Trus;W W Newcomb;J C Brown

  162
  Citations