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Medicine

D-Index
80
Citations
20416
World Ranking
17253
National Ranking
8645

Overview

Richard Childs is affiliated with the National Institutes of Health in the United States and has contributed extensively to the field of medicine, particularly within immunology, oncology, infectious diseases, hematology, and molecular biology. Their research encompasses both fundamental and clinical aspects across these disciplines.

The scientist's recent publications cover various topics including COVID-19 clinical research, immunotherapy, and cellular therapies. Notable papers include:

  • Compassionate Use of Remdesivir for Patients with Severe Covid-19, 2020, New England Journal of Medicine
  • Fostamatinib Inhibits Neutrophils Extracellular Traps Induced by COVID-19 Patient Plasma: A Potential Therapeutic, 2020, The Journal of Infectious Diseases
  • In Vivo Tracking of Adoptively Transferred Natural Killer Cells in Rhesus Macaques Using 89Zirconium-Oxine Cell Labeling and PET Imaging, 2020, Clinical Cancer Research
  • Fostamatinib for the Treatment of Hospitalized Adults With Coronavirus Disease 2019: A Randomized Trial, 2021, Clinical Infectious Diseases
  • Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion, 2021, Molecular Therapy - Methods & Clinical Development

Their collaboration network includes frequent co-authors such as Robert Reger, Xin Tian, Mala Chakraborty, Georg Aue, and Anthony F. Suffredini, indicating a broad interdisciplinary research environment.

Richard Childs has published widely in several respected publication venues, with multiple contributions to the following journals:

  • Blood
  • Bone Marrow Transplantation
  • Regular and Young Investigator Award Abstracts
  • Molecular Therapy - Methods & Clinical Development
  • British Journal of Haematology

The main fields of study focus on medicine, with an emphasis on the following subfields:

  • Immunology
  • Oncology
  • Infectious Diseases
  • Hematology
  • Molecular Biology

The primary research topics include:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Genomics and Diagnostics
  • Virus-based gene therapy research

Best Publications

  • Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation.

    Childs R;Chernoff A;Contentin N;Bahceci E

  • High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin.

    Toshihiko Tanno;Natarajan V Bhanu;Patricia A Oneal;Sung-Ho Goh

  • Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation

    Kairong Cui;Chongzhi Zang;Tae-Young Roh;Dustin E. Schones

  • Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses.

    R. Childs;E. Clave;N. Contentin;D. Jayasekera

  • Allogeneic Hematopoietic Stem-Cell Transplantation for Sickle Cell Disease

    Matthew M. Hsieh;Elizabeth M. Kang;Courtney D. Fitzhugh;M. Beth Link

  • Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial.

    Mohammed Z H Farooqui;Janet Valdez;Sabrina Martyr;Georg Aue

  • Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?

    Pawel Muranski;Andrea Boni;Claudia Wrzesinski;Deborah E Citrin

  • Establishment of complete and mixed donor chimerism after allogeneic lymphohematopoietic transplantation : recommendations from a workshop at the 2001 Tandem Meetings of the International Bone Marrow Transplant Registry and the American Society of Blood and Marrow Transplantation

    Joseph H. Antin;Richard Childs;Alexandra H. Filipovich;Sergio Giralt

  • Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

    Katayoun Rezvani;Matthias Grube;Matthias Grube;Jason M. Brenchley;Jason M. Brenchley;Giuseppe Sconocchia;Giuseppe Sconocchia

  • Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples

    Wenfei Jin;Qingsong Tang;Mimi Wan;Kairong Cui

  • Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells

    Maria Berg;Andreas Lundqvist;Philip McCoy;Leigh Samsel

  • Therapeutic approaches to enhance natural killer cell cytotoxicity against cancer: the force awakens

    Richard W. Childs;Mattias Carlsten

  • Successful Treatment of Metastatic Renal Cell Carcinoma With a Nonmyeloablative Allogeneic Peripheral-Blood Progenitor-Cell Transplant: Evidence for a Graft-Versus-Tumor Effect

    Richard W. Childs;Emmanuel Clave;John Tisdale;Michelle Plante

  • Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia

    B N Savani;S Mielke;S Adams;M Uribe

  • Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.

    Yoshiyuki Takahashi;Nanae Harashima;Sachiko Kajigaya;Hisayuki Yokoyama

  • Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells.

    Takehito Igarashi;Jason Wynberg;Ramprasad Srinivasan;Brian Becknell

  • Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury.

    Hideo Yasuda;Asada Leelahavanichkul;Shinichiro Tsunoda;James W. Dear

  • Genetic Manipulation of NK Cells for Cancer Immunotherapy: Techniques and Clinical Implications

    Mattias Carlsten;Richard W. Childs

  • Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase 2 study

    Inhye E. Ahn;Mohammed Z. H. Farooqui;Xin Tian;Janet Valdez

  • Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation.

    Scott R. Solomon;Stephan Mielke;Stephan Mielke;Bipin N. Savani;Bipin N. Savani;Aldemar Montero;Aldemar Montero

Frequent Co-Authors

Andreas Lundqvist
Andreas Lundqvist Karolinska Institute
A. John Barrett
A. John Barrett National Institutes of Health
Susan F. Leitman
Susan F. Leitman National Institutes of Health
Bipin N. Savani
Bipin N. Savani Vanderbilt University Medical Center
David F. Stroncek
David F. Stroncek National Institutes of Health
Cynthia E. Dunbar
Cynthia E. Dunbar National Institutes of Health
Neal S. Young
Neal S. Young National Institutes of Health
Nancy L. Geller
Nancy L. Geller National Institutes of Health
John F. Tisdale
John F. Tisdale National Institutes of Health
J. Philip McCoy
J. Philip McCoy National Institutes of Health

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