World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
12966
World Ranking
15482
National Ranking
6460

Overview

Li Shen is affiliated with the Icahn School of Medicine at Mount Sinai in the United States and specializes in fields spanning Medicine and Biochemistry, Genetics and Molecular Biology. Their research output includes 142 publications in medicine and 134 in biochemistry and related molecular biology disciplines, with deep involvement in molecular biology, oncology, cancer research, immunology, and pulmonary and respiratory medicine.

The scientist's work addresses several main topics, such as lung cancer research studies, microtubule and mitosis dynamics, RNA modifications and cancer, antimicrobial resistance in Staphylococcus, bacterial biofilms and quorum sensing, cancer-related molecular pathways, and microRNA in disease regulation.

They have frequently published in several scientific venues, with the highest number of publications appearing in Cancer Research, followed by Clinical Cancer Research, bioRxiv, Microbiology Spectrum, and Frontiers in Immunology.

Li Shen has collaborated extensively, with frequent coauthors including Jing Wang, Faye M. Johnson, Lauren A. Byers, John V. Heymach, and Carl M. Gay. These collaborations highlight a network of researchers working together in related biomedical and cancer research fields.

Selected recent publications by Li Shen include:

  • "Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo-controlled trial," 2021, The Lancet Neurology
  • "A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components," 2020, Science Translational Medicine
  • "IL6 Mediates Suppression of T- and NK-cell Function in EMT-associated TKI-resistant EGFR-mutant NSCLC," 2023, Clinical Cancer Research
  • "Safety and efficacy of risdiplam in patients with type 1 spinal muscular atrophy (FIREFISH part 2): secondary analyses from an open-label trial," 2022, The Lancet Neurology
  • "CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance," 2023, Cancer Cell

Best Publications

  • An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

    Lauren Averett Byers;Lixia Diao;Jing Wang;Pierre Saintigny

  • Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites.

    S. Colella;L. Shen;Keith A Baggerly;J. P.J. Issa

  • Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1

    Lauren Averett Byers;Jing Wang;Monique B. Nilsson;Junya Fujimoto

  • Entinostat neutralizes myeloid derived suppressor cells and enhances the antitumor effect of PD-1 inhibition in murine models of lung and renal cell carcinoma

    Ashley Orillion;Ashley Orillion;Ayumi Hashimoto;Nur P Damayanti;Li Shen

  • Combined Tumor Suppressor Defects Characterize Clinically Defined Aggressive Variant Prostate Cancers

    Ana M. Aparicio;Li Shen;Elsa M Li Ning Tapia;Jing-Fang Lu

  • Immune Heterogeneity of Glioblastoma Subtypes: Extrapolation from the Cancer Genome Atlas

    Tiffany A Doucette;Ganesh Rao;Arvind Rao;Li Shen

  • Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models

    Li Shen;Michael Ciesielski;Swathi Ramakrishnan;Kiersten M. Miles

  • Reversible Epithelial to Mesenchymal Transition and Acquired Resistance to Sunitinib in Patients with Renal Cell Carcinoma: Evidence from a Xenograft Study

    Hans J. Hammers;Henk M. Verheul;Henk M. Verheul;Brenda Salumbides;Rajni Sharma

  • miR-34a-5p suppresses colorectal cancer metastasis and predicts recurrence in patients with stage II/III colorectal cancer

    J Gao;N Li;Y Dong;S Li

  • A promising biodegradable magnesium alloy suitable for clinical vascular stent application

    Lin Mao;Li Shen;Jiahui Chen;Xiaobo Zhang

  • The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer

    Vassiliki Papadimitrakopoulou;J. Jack Lee;Ignacio I. Wistuba;Anne S. Tsao

  • Mesenchymal Stem Cells Regulate Blood-Brain Barrier Integrity Through TIMP3 Release After Traumatic Brain Injury

    Tyler Menge;Yuhai Zhao;Jing Zhao;Kathryn Wataha

  • Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates.

    Vida Chitsazzadeh;Cristian Coarfa;Jennifer A. Drummond;Tri Nguyen

  • Synthetic ePTFE grafts coated with an anti-CD133 antibody-functionalized heparin/collagen multilayer with rapid in vivo endothelialization properties.

    Shuyang Lu;Peng Zhang;Xiaoning Sun;Feirong Gong

  • YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage

    Eric Stefano Ciamporcero;Eric Stefano Ciamporcero;H Shen;S Ramakrishnan;S Yu Ku

  • Enhanced Bioactivity of Mg–Nd–Zn–Zr Alloy Achieved with Nanoscale MgF2 Surface for Vascular Stent Application

    Lin Mao;Li Shen;Jiahui Chen;Yu Wu;Yu Wu

  • A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components

    Monique B. Nilsson;Huiying Sun;Jacqulyne Robichaux;Matthias Pfeifer

  • Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer

    Andrea Weiss;Andrea Weiss;Xianting Ding;Judy R. van Beijnum;Ieong Wong

  • Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer.

    Heath Skinner;Uma Giri;Liang P. Yang;Manish Kumar

  • Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network

    G.D. Demetri;C.R. Antonescu;B. Bjerkehagen;J.V.M.G. Bovée

Frequent Co-Authors

Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Rachael L. Neve
Rachael L. Neve Harvard University
Jian Feng
Jian Feng University at Buffalo, State University of New York
Yi Zhang
Yi Zhang Harvard University
Heng-Yu Fan
Heng-Yu Fan Zhejiang University
Gustavo Turecki
Gustavo Turecki Douglas Mental Health University Institute
Rosemary C. Bagot
Rosemary C. Bagot McGill University
Bin Zhang
Bin Zhang Icahn School of Medicine at Mount Sinai
Xin-Hua Feng
Xin-Hua Feng Zhejiang University
Ja Wook Koo
Ja Wook Koo Korea Brain Research Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Graduates in Biology and Biochemistry often branch into allied health fields, where online degrees are increasingly popular. One in-demand pathway is Health Information Management (HIM), prized for its blend of technology and healthcare. Many students seek the most affordable online health information management degree programs to launch their careers in this expanding field.

Medical coding is another top option, offering strong job growth and good earning potential. To learn more about medical coding jobs salary and entry pathways, explore online coursework and short-term certifications available nationwide.

Choosing between credentials such as a certified professional coder (CPC) or a certified coding specialist (CCS) is an important decision, as each offers different advantages, costs, and salary prospects.

Is medical coding a good job for science graduates? Consider your personality, work environment preferences, and salary goals. For an honest look at this career, read about the is medical coding a good job question before making your choice.

Best Scientists Citing Li Shen

Trending Scientists

Recently Published Articles