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Chemistry

D-Index
63
Citations
11524
World Ranking
8603
National Ranking
303

Overview

Mouad Alami is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research activity focuses primarily on chemistry, with significant contributions to organic chemistry and related interdisciplinary fields.

Their work encompasses specific subfields including:

  • Organic Chemistry
  • Molecular Biology
  • Materials Chemistry
  • Oncology
  • Pharmacology

The research topics covered by Mouad Alami include:

  • Catalytic C-H Functionalization Methods
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Cyclopropane Reaction Mechanisms
  • Sulfur-Based Synthesis Techniques
  • Synthesis and Catalytic Reactions
  • Synthetic Organic Chemistry Methods

The scientist's recent publications illustrate areas of application and methodology in catalytic processes and organic synthesis. Notable papers are:

  • "Diastereoselective Pd-Catalyzed Anomeric C(sp3)-H Activation: Synthesis of α-(Hetero)aryl C-Glycosides", 2021, ACS Catalysis
  • "Developments of isoCombretastatin A-4 derivatives as highly cytotoxic agents", 2020, European Journal of Medicinal Chemistry
  • "Electrochemical nickel-catalyzed Migita cross-coupling of 1-thiosugars with aryl, alkenyl and alkynyl bromides", 2020, Chemical Communications
  • "Recent advances in the synthesis of pyrido[1,2-a]indoles", 2021, Organic & Biomolecular Chemistry
  • "Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors", 2022, European Journal of Medicinal Chemistry

Mouad Alami frequently publishes in several chemistry-focused journals and databases including:

  • The Cambridge Structural Database
  • European Journal of Medicinal Chemistry
  • The Journal of Organic Chemistry
  • European Journal of Organic Chemistry
  • Chemical Communications

Collaborations form an important aspect of this scientist's output, with frequent co-authors being:

  • Samir Messaoudi
  • Abdallah Hamzé
  • Pascal Retailleau
  • Olivier Provot
  • Christine Tran

Best Publications

  • Sulfinate derivatives: dual and versatile partners in organic synthesis

    Jessy Aziz;Samir Messaoudi;Mouad Alami;Abdallah Hamze

  • Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent.

    Samir Messaoudi;Bret Tréguier;Abdallah Hamze;Olivier Provot

  • An Efficient palladium-catalysed reaction of vinyl and aryl halides or triflates with terminal alkynes

    Unknown

  • Transition-Metal-Catalyzed Direct C–H Alkenylation, Alkynylation, Benzylation, and Alkylation of (Hetero)arenes

    Samir Messaoudi;Jean-Daniel Brion;Mouâd Alami

  • Palladium(II)-Catalyzed Oxidative Arylation of Quinoxalin-2(1H)-ones with Arylboronic Acids

    Amandine Carrër;Jean-Daniel Brion;Samir Messaoudi;Mouad Alami

  • New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90.

    Gaëlle Le Bras;Christine Radanyi;Jean-François Peyrat;Jean-Daniel Brion

  • A CONVENIENT ROUTE TO UNSYMMETRICAL CONJUGATED DIYNES

    Mouâd Alami;Fabiola Ferri

  • Discovery of Isoerianin Analogues as Promising Anticancer Agents

    Samir Messaoudi;Abdallah Hamze;Olivier Provot;Bret Tréguier

  • 2-Aminobiphenyl Palladacycles: The “Most Powerful” Precatalysts in C–C and C–Heteroatom Cross-Couplings

    Alexandre Bruneau;Maxime Roche;Mouad Alami;Samir Messaoudi

  • Recent Advances in Hsp90 Inhibitors as Antitumor Agents

    Samir Messaoudi;Jean F. Peyrat;Jean D. Brion;Mouâd Alami

  • DMSO–PdI2 as a powerful oxidizing couple of alkynes into benzils: one-pot synthesis of nitrogen-containing five- or six-membered heterocycles

    Céline Mousset;Olivier Provot;Abdallah Hamze;Jérôme Bignon

  • Synthesis and antitumor activity of benzils related to combretastatin A-4

    Céline Mousset;Anne Giraud;Olivier Provot;Abdallah Hamze

  • Expeditious synthesis of 1,1-diarylethylenes related to isocombretastatin A-4 (isoCA-4) via palladium-catalyzed arylation of N-tosylhydrazones with aryl triflates

    Bret Tréguier;Abdallah Hamze;Olivier Provot;Jean-Daniel Brion

  • Pd-catalyzed reaction of sterically hindered hydrazones with aryl halides: synthesis of tetra-substituted olefins related to iso-combretastatin A4.

    Etienne Brachet;Abdallah Hamze;Jean-François Peyrat;Jean-Daniel Brion

  • Microwave-assisted Pd(OH)2-catalyzed direct C−H arylation of free-(NH2) adenines with aryl halides

    Sophian Sahnoun;Samir Messaoudi;Jean Francois Peyrat;Jean-Daniel Brion

  • Copper-catalyzed reductive coupling of tosylhydrazones with amines: A convenient route to α-branched amines

    Abdallah Hamze;Bret Tréguier;Jean-Daniel Brion;Mouâd Alami

  • Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents.

    Abdallah Hamze;Anne Giraud;Samir Messaoudi;Olivier Provot

  • Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90).

    Christine Radanyi;Gaëlle Le Bras;Samir Messaoudi;Céline Bouclier

  • Palladium-catalyzed decarboxylative coupling of quinolinone-3-carboxylic acids and related heterocyclic carboxylic acids with (hetero)aryl halides.

    Samir Messaoudi;Jean-Daniel Brion;Mouad Alami

  • Organomanganese(II) reagents. XV: Conjugate addition of organomanganese reagents to alkylidenemalonic esters and related compounds

    Gérard Cahiez;Mouad Alami

  • A General Copper Powder-Catalyzed Ullmann-Type Reaction of 3-Halo-4(1H)-quinolones With Various Nitrogen-Containing Nucleophiles

    Davide Audisio;Samir Messaoudi;Jean-François Peyrat;Jean-Daniel Brion

  • An efficient palladium-catalyzed reaction of vinyl chlorides with terminal acetylenes

    Unknown

Frequent Co-Authors

Jean-Daniel Brion
Jean-Daniel Brion Centre national de la recherche scientifique, CNRS
Samir Messaoudi
Samir Messaoudi University of Paris-Saclay
Patrick Couvreur
Patrick Couvreur University of Paris-Saclay
Markus Hengstschläger
Markus Hengstschläger Medical University of Vienna
Jack-Michel Renoir
Jack-Michel Renoir Institut Gustave Roussy
Daniel A. Lawrence
Daniel A. Lawrence University of Michigan–Ann Arbor
Montserrat Gómez
Montserrat Gómez Paul Sabatier University
Elias Fattal
Elias Fattal University of Paris-Saclay

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