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Overview

Jerome Waser is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland, with a research focus primarily in the field of Chemistry.

The scientist's work is concentrated within the subfields of Organic Chemistry, Materials Chemistry, Molecular Biology, Pharmaceutical Science, and Inorganic Chemistry.

Areas of research include:

  • Catalytic C-H Functionalization Methods
  • Cyclopropane Reaction Mechanisms
  • Oxidative Organic Chemistry Reactions
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Chemical Synthesis and Analysis
  • Radical Photochemical Reactions

Recent publications by Jerome Waser include:

  • Catalytic Enantioselective Ring-Opening Reactions of Cyclopropanes, 2020, Chemical Reviews
  • Photocatalyzed [2σ + 2σ] and [2σ + 2π] Cycloadditions for the Synthesis of Bicyclo[3.1.1]heptanes and 5- or 6-Membered Carbocycles, 2023, Journal of the American Chemical Society
  • Photocatalysis with organic dyes: facile access to reactive intermediates for synthesis, 2020, Beilstein Journal of Organic Chemistry
  • Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells, 2020, Angewandte Chemie International Edition
  • Cys-Cys and Cys-Lys Stapling of Unprotected Peptides Enabled by Hypervalent Iodine Reagents, 2021, Angewandte Chemie International Edition

Jerome Waser has published extensively in several venues, with frequent contributions to:

  • Zenodo (CERN European Organization for Nuclear Research)
  • The Cambridge Structural Database
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Organic Letters

The scientist often collaborates with several researchers, including:

  • Matthew D. Wodrich
  • Eliott Le Du
  • Emma G. L. Robert
  • Farzaneh Fadaei-Tirani
  • Rosario Scopelliti

Best Publications

  • Hydrazines and azides via the metal-catalyzed hydrohydrazination and hydroazidation of olefins.

    Jerome Waser;Boris Gaspar;Hisanori Nambu;Erick M. Carreira

  • Catalytic Enantioselective Ring-Opening Reactions of Cyclopropanes.

    Vincent Pirenne;Bastian Muriel;Jerome Waser

  • Direct Alkynylation of Indole and Pyrrole Heterocycles

    Jonathanâ P. Brand;Julie Charpentier;Jérôme Waser

  • Electrophilic alkynylation: the dark side of acetylene chemistry

    Jonathan P. Brand;Jérôme Waser

  • Cyclic Hypervalent Iodine Reagents for Atom-Transfer Reactions: Beyond Trifluoromethylation.

    Yifan Li;Durga Prasad Hari;Maria Victoria Vita;Jerome Waser

  • Benziodoxole-based hypervalent iodine reagents for atom-transfer reactions

    Jonathan P. Brand;Davinia Fernández González;Stefano Nicolai;Jérôme Waser

  • Cyclization and annulation reactions of nitrogen-substituted cyclopropanes and cyclobutanes.

    F. de Nanteuil;F. De Simone;R. Frei;F. Benfatti

  • Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides

    Jérôme Waser;and Hisanori Nambu;Erick M. Carreira

  • Convenient Synthesis of Alkylhydrazides by the Cobalt-Catalyzed Hydrohydrazination Reaction of Olefins and Azodicarboxylates

    Jérôme Waser;Erick M Carreira

  • Direct Alkynylation of Thiophenes: Cooperative Activation of TIPS–EBX with Gold and Brønsted Acids

    Jonathan P. Brand;Jérôme Waser

  • Cyclic Hypervalent Iodine Reagents: Enabling Tools for Bond Disconnection via Reactivity Umpolung

    Durga Prasad Hari;Paola Caramenti;Jerome Waser

  • Fast and highly chemoselective alkynylation of thiols with hypervalent iodine reagents enabled through a low energy barrier concerted mechanism.

    Reto Frei;Matthew D Wodrich;Durga Prasad Hari;Pierre-Antoine Borin

  • Cyclization and Cycloaddition Reactions of Cyclopropyl Carbonyls and Imines

    Filippo De Simone;Jérôme Waser

  • Room-Temperature Decarboxylative Alkynylation of Carboxylic Acids Using Photoredox Catalysis and EBX Reagents

    Franck Le Vaillant;Thibaut Courant;Jerome Waser

  • Gold-Catalyzed Regioselective Synthesis of 2- and 3-Alkynyl Furans

    Yifan Li;Jonathan P. Brand;Jérôme Waser

  • Ethynyl‐1,2‐benziodoxol‐3(1 H)‐one (EBX): An Exceptional Reagent for the Ethynylation of Keto, Cyano, and Nitro Esters

    Davinia Fernández González;Jonathan Patrick Brand;Jérôme Waser

  • A highly chemoselective and practical alkynylation of thiols.

    Reto Frei;Jérôme Waser

  • Dynamic Kinetic Asymmetric [3 + 2] Annulation Reactions of Aminocyclopropanes

    Florian de Nanteuil;Eloisa Serrano;Daniele Perrotta;Jerome Waser

  • A Palladium-Catalyzed Aminoalkynylation Strategy towards Bicyclic Heterocycles: Synthesis of (±)-Trachelanthamidine

    Stefano Nicolai;Cyril Piemontesi;Jérôme Waser

  • Pd-Catalyzed Intramolecular Oxyalkynylation of Alkenes with Hypervalent Iodine

    Stefano Nicolai;Stéphane Erard;Davinia Fernández González;Jérôme Waser

  • Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides.

    Jerome Waser;Hisanori Nambu;Erick M. Carreira

Frequent Co-Authors

Rosario Scopelliti
Rosario Scopelliti École Polytechnique Fédérale de Lausanne
Kay Severin
Kay Severin École Polytechnique Fédérale de Lausanne
Barry M. Trost
Barry M. Trost Stanford University
Clémence Corminboeuf
Clémence Corminboeuf École Polytechnique Fédérale de Lausanne
Florenz Sasse
Florenz Sasse Technische Universität Braunschweig
Xile Hu
Xile Hu École Polytechnique Fédérale de Lausanne
Baohong Liu
Baohong Liu Fudan University
Nicolai Cramer
Nicolai Cramer École Polytechnique Fédérale de Lausanne
Kevin Sivula
Kevin Sivula École Polytechnique Fédérale de Lausanne

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