Dirk Troost

Overview

Best Publications

• Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

  Marcel Kool;Jan Koster;Jens Bunt;Nancy E. Hasselt

  827
  Citations

• Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

  Manuela Neumann;Manuela Neumann;Linda K. Kwong;Edward B. Lee;Elisabeth Kremmer

  589
  Citations

• TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.

  Nigel J. Cairns;Manuela Neumann;Manuela Neumann;Eileen H. Bigio;Ida E. Holm

  586
  Citations

• IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors.

  Fonnet E. Bleeker;Simona Lamba;Sieger Leenstra;Dirk Troost

  471
  Citations

• Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2–21.3

  Caroline Vance;Ammar Al-Chalabi;Deborah Ruddy;Bradley N. Smith

  470
  Citations

• The IL-1β system in epilepsy-associated malformations of cortical development

  T. Ravizza;K. Boer;S. Redeker;W.G.M. Spliet

  372
  Citations

• Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations

  Ian R. Mackenzie;Thomas Arzberger;Thomas Arzberger;Elisabeth Kremmer;Elisabeth Kremmer;Dirk Troost

  366
  Citations

• Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy.

  Eleonora Aronica;Erwin A. Van Vliet;Oleg A. Mayboroda;Dirk Troost

  361
  Citations

• Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins.

  Eleonora Aronica;Jan A. Gorter;Helen Ijlst-Keizers;Annemieke J. Rozemuller

  351
  Citations

• The prognostic IDH1 R132 mutation is associated with reduced NADP + -dependent IDH activity in glioblastoma

  Fonnet E. Bleeker;Nadia A. Atai;Simona Lamba;Ard Jonker

  351
  Citations

• NLRP3 Inflammasome Is Expressed by Astrocytes in the SOD1 Mouse Model of ALS and in Human Sporadic ALS Patients

  Sonja Johann;Marius Heitzer;Mithila Kanagaratnam;Anand Goswami

  319
  Citations

• Expression and Cellular Distribution of Multidrug Resistance–related Proteins in the Hippocampus of Patients with Mesial Temporal Lobe Epilepsy

  Eleonora Aronica;Jan A. Gorter;Marja Ramkema;Sandra Redeker

  292
  Citations

• Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex.

  K. Boer;F. Jansen;M. Nellist;S. Redeker

  285
  Citations

• Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy: focal cortical dysplasia and glioneuronal tumors.

  E.M.A. Aronica;J.A. Gorter;G.H. Jansen;C.W.M. van Veelen

  274
  Citations

• Toll-like receptor signaling in amyotrophic lateral sclerosis spinal cord tissue.

  M. Casula;A.M. Iyer;W.G.M. Spliet;J.J. Anink

  265
  Citations

• Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

  Marcel Naumann;Arun Pal;Anand Goswami;Xenia Lojewski

  255
  Citations

• Complement activation in experimental and human temporal lobe epilepsy.

  E. Aronica;K. Boer;E.A. van Vliet;S. Redeker

  252
  Citations

• The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone

  Remco J. Molenaar;Dagmar Verbaan;Simona Lamba;Carlo Zanon

  243
  Citations

• The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids

  P C De Witt Hamer;A A G Van Tilborg;P P Eijk;P Sminia

  242
  Citations

• Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers

  Ian R. A. Mackenzie;Petra Frick;Friedrich A. Grässer;Tania F. Gendron

  233
  Citations