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Biology and Biochemistry

D-Index
75
Citations
17841
World Ranking
5388
National Ranking
2554

Research.com Recognitions

  • 1994 - Fellow of the American Academy of Arts and Sciences
  • 1985 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William N. Kelley is affiliated with the University of Pennsylvania in the United States. Their research primarily spans the field of Medicine, with a focus on subfields including Neurology and Epidemiology.

Their scholarly contributions address several key topics, among which are:

  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intracranial Aneurysms: Treatment and Complications
  • Acute Ischemic Stroke Management

Kelley's recent paper, published in 2024, is titled Early Pharmacologic Therapy in Patients With Blunt Cerebrovascular Injury and TBI: Is it Safe and Effective? An EAST Multicenter Study. This article appeared in the journal The American Surgeon.

Frequent co-authors of Kelley include:

  • Khaled Zreik
  • Anna K. Gergen
  • Jamie Williams
  • Lewis E. Jacobson
  • Jeffry Nahmias

The American Surgeon is noted as a publication venue for Kelley's work, reflecting their engagement with clinical surgical research contexts.

Their professional recognitions include fellowships awarded by prominent organizations:

  • Fellow of the American Academy of Arts and Sciences (1994)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1985)

Best Publications

  • Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

    J. Edwin Seegmiller;Frederick M. Rosenbloom;William N. Kelley

  • The role of adenosine and 2'-deoxyadenosine in mammalian cells.

    Irving H. Fox;William N. Kelley

  • A specific enzyme defect in gout associated with overproduction of uric acid

    W N Kelley;F M Rosenbloom;J F Henderson;J E Seegmiller

  • Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency in Gout

    William N. Kelley;Martin L. Greene;Frederick M. Rosenbloom;J. Frank Henderson

  • Biochemical Evidence of Dysfunction of Brain Neurotransmitters in the Lesch-Nyhan Syndrome

    Kenneth G. Lloyd;Oleh Hornykiewicz;Lynne Davidson;Katherine Shannak

  • Human adenosine deaminase. Distribution and properties.

    M B Van der Weyden;W N Kelley

  • Textbook of internal medicine

    William N Kelley;Vincent T DeVita;Herbert L. Dupont

  • Biochemical bases of accelerated purine biosynthesis de novo in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.

    F M Rosenbloom;J F Henderson;I C Caldwell;W N Kelley

  • Phosphoribosylpyrophosphate in Man: Biochemical and Clinical Significance

    Irving H. Fox;William N. Kelley

  • Studies on the mechanism of fructose-induced hyperuricemia in man.

    Fox Ih;Kelley Wn

  • Purinogenic immunodeficiency diseases: selective toxicity of deoxyribonucleosides for T cells.

    Beverly S. Mitchell;Edwin Mejias;Peter E. Daddona;William N. Kelley

  • Human Phosphoribosylpyrophosphate Synthetase DISTRIBUTION, PURIFICATION, AND PROPERTIES

    Irving H. Fox;William N. Kelley

  • Inherited Disorder of Purine Metabolism: Correlation Between Central Nervous System Dysfunction and Biochemical Defects

    F M Rosenbloom;W N Kelley;J Miller;J F Henderson

  • Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties.

    Edward W. Holmes;John A. McDonald;Joe M. McCord;James B. Wyngaarden

  • A role for adenosine deaminase in human monocyte maturation.

    D Fischer;M B Van der Weyden;R Snyderman;W N Kelley

  • Human phosphoribosylpyrophosphate synthetase. Kinetic mechanism and end product inhibition.

    Irving H. Fox;William N. Kelley

  • Measurement of DNA in cultured human cells

    Albert Leyva;William N. Kelley

  • Kinetic studies of hypoxanthine-guanine phosphoribosyltransferase.

    J F Henderson;L W Brox;W N Kelley;F M Rosenbloom

  • Expression of human HPRT mRNA in brains of mice infected with a recombinant herpes simplex virus-1 vector.

    Thomas D. Palella;Yuji Hidaka;Larry J. Silverman;Myron Levine

  • Allopurinol: alteration in pyrimidine metabolism in man.

    William N. Kelley;Thomas D. Beardmore

Frequent Co-Authors

James M. Wilson
James M. Wilson University of Pennsylvania
Beverly L. Davidson
Beverly L. Davidson Children's Hospital of Philadelphia
Arnold E. Postlethwaite
Arnold E. Postlethwaite University of Tennessee Health Science Center
Beverly S. Mitchell
Beverly S. Mitchell Stanford University
Stuart H. Orkin
Stuart H. Orkin Harvard University
Donna S. Shewach
Donna S. Shewach University of Michigan–Ann Arbor
Naoyuki Kamatani
Naoyuki Kamatani StaGen (Japan)
Michael A. Frohman
Michael A. Frohman Stony Brook University
Joseph C. Glorioso
Joseph C. Glorioso University of Pittsburgh
Anne B. Young
Anne B. Young Harvard University

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