D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 61 Citations 15,411 128 World Ranking 2289 National Ranking 1134

Research.com Recognitions

Awards & Achievements

1994 - Fellow of the American Association for the Advancement of Science (AAAS)

1976 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Theodore Friedmann focuses on Molecular biology, Genetic enhancement, Genetics, Virology and Gene. His Molecular biology study incorporates themes from Cell culture, Retrovirus, Viral replication and Hypoxanthine-guanine phosphoribosyltransferase, Hypoxanthine Phosphoribosyltransferase. The concepts of his Genetic enhancement study are interwoven with issues in Bioinformatics, Psychotherapist, Viral vector, Disease and Computational biology.

His studies examine the connections between Virology and genetics, as well as such issues in Vector, with regards to Titer. In his research, Zebrafish is intimately related to Transgene, which falls under the overarching field of Virus. His Genetic transfer research includes elements of Molecular genetics and Somatic cell.

His most cited work include:

  • Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells (1321 citations)
  • Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells (721 citations)
  • Progress toward human gene therapy (627 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Molecular biology, Genetic enhancement, Gene, Genetics and Virology. He interconnects Hypoxanthine-guanine phosphoribosyltransferase, Mutant, Transfection and Virus, Vesicular stomatitis virus in the investigation of issues within Molecular biology. Theodore Friedmann focuses mostly in the field of Genetic enhancement, narrowing it down to topics relating to Gene transfer and, in certain cases, Engineering ethics.

His study in Gene expression, Reporter gene, Phenotype, Plasmid and Genetically modified organism are all subfields of Gene. His Virology research incorporates themes from Vector and Viral vector. His Retrovirus research includes themes of Viral envelope, Transduction and Cell biology.

He most often published in these fields:

  • Molecular biology (33.90%)
  • Genetic enhancement (24.58%)
  • Gene (22.46%)

What were the highlights of his more recent work (between 2006-2021)?

  • Genetic enhancement (24.58%)
  • Hypoxanthine-guanine phosphoribosyltransferase (13.14%)
  • Bioinformatics (8.90%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Genetic enhancement, Hypoxanthine-guanine phosphoribosyltransferase, Bioinformatics, Disease and Genetics. His Genetic enhancement research is multidisciplinary, incorporating elements of Vector, Gene transfer and Leukemia. His work deals with themes such as Virus, Neutralizing antibody, Transfection and Glycoprotein, which intersect with Vector.

His Hypoxanthine-guanine phosphoribosyltransferase research is classified as research in Gene. His work in Genetics is not limited to one particular discipline; it also encompasses Computational biology. He has researched Genetic therapy in several fields, including Human genome, Virology, Metabolic disease, Viral vector and Genome editing.

Between 2006 and 2021, his most popular works were:

  • Human Oxidation-Specific Antibodies Reduce Foam Cell Formation and Atherosclerosis Progression (78 citations)
  • Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase. (38 citations)
  • Deficiency of the Housekeeping Gene Hypoxanthine–Guanine Phosphoribosyltransferase (HPRT) Dysregulates Neurogenesis (38 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary scientific interests are in Cell biology, Hypoxanthine-guanine phosphoribosyltransferase, Molecular biology, Gene knockdown and Engineering ethics. His Hypoxanthine-guanine phosphoribosyltransferase study falls within the topics of Gene and Genetics. His research in Gene tackles topics such as Dopaminergic which are related to areas like Cancer research.

His work on Neurogenesis and SOX2 as part of his general Genetics study is frequently connected to Platelet activation, thereby bridging the divide between different branches of science. His biological study spans a wide range of topics, including RNA and DNA. His Engineering ethics research also works with subjects such as

  • Gene doping together with Dehumanization and Control,
  • Public policy which connect with Gene transfer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

Jane C. Burns;Theodore Friedmann;Wolfgang Driever;Michelle Burrascano.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1822 Citations

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

Huei-Jen Su Huang;Jiing-Kuan Yee;Jin-Yuh Shew;Phang-Lang Chen.
Science (1988)

1131 Citations

Progress toward human gene therapy

Theodore Friedmann.
Science (1989)

977 Citations

A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes

Jiing-Kuan Yee;Atsushi Miyanohara;Patricia Laporte;Kathy Bouic.
Proceedings of the National Academy of Sciences of the United States of America (1994)

743 Citations

Gene Therapy for Human Genetic Disease

Theodore Friedmann;Richard Roblin.
Science (1972)

740 Citations

Generation of high-titer pseudotyped retroviral vectors with very broad host range.

Jiing-Kuan Yee;Theodore Friedmann;Jane C. Burns.
Methods in Cell Biology (1994)

722 Citations

Base sequence studies of 300 nucleotide renatured repeated human DNA clones

Prescott L. Deininger;Douglas J. Jolly;Carol M. Rubin;Theodore Friedmann.
Journal of Molecular Biology (1981)

696 Citations

Advances in genetics

M. Demerec;Ernst W. Caspari;J. M. Thoday;John G. Scandalios.
Advances in Genetics (1947)

638 Citations

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

Michael B. Rosenberg;Theodore Friedmann;Robin C. Robertson;Mark Tuszynski.
Science (1988)

582 Citations

Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.

Mark Schumacher;Shelley Camp;Yves Maulet;Michael Newton.
Nature (1986)

556 Citations

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