World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
74
Citations
21219
World Ranking
2096
National Ranking
998

Research.com Recognitions

  • 1987 - Fellow of Alfred P. Sloan Foundation

Overview

Jay M. Baraban is a researcher affiliated with Johns Hopkins University in the United States. Their work spans several interconnected disciplines, notably within biochemistry, genetics, molecular biology, medicine, and neuroscience. Over their career, they have contributed extensively to understanding molecular and cellular mechanisms relevant to physiology and disease.

The main fields of study in their research include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Within these broad areas, their subfields of study are:

  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Cellular and Molecular Neuroscience
  • Cancer Research
  • Physiology

Their research covers a wide range of topics such as:

  • Adipose Tissue and Metabolism
  • Genetics and Neurodevelopmental Disorders
  • RNA Research and Splicing
  • Cardiovascular Health and Disease Prevention
  • MicroRNA in disease regulation
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms

Several recent publications illustrate the themes and scope of Jay M. Baraban's work. These include:

  • "Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA," 2023, published in Neuron
  • "Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity," 2020, published in Molecular Brain
  • "Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion," 2020, published in Molecular Metabolism
  • "Degradation of Premature-miR-181b by the Translin/Trax RNase Increases Vascular Smooth Muscle Cell Stiffness," 2021, published in Hypertension
  • "Deficient mitochondrial respiration in astrocytes impairs trace fear conditioning and increases naloxone-precipitated aversion in morphine-dependent mice," 2022, published in Glia

Jay M. Baraban has published multiple papers in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Brain
  • Neuron
  • Molecular Metabolism
  • Hypertension

Frequent collaborators in their research include:

  • Xiuping Fu
  • Aparna Shah
  • Mahesh Shivarama Shetty
  • Ted Abel
  • Kellie L. Tamashiro

Jay M. Baraban was recognized as a Fellow of the Alfred P. Sloan Foundation in 1987.

Best Publications

  • Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

    Andrew J. Cole;David W. Saffen;Jay M. Baraban;Paul F. Worley

  • Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance

    Jin Sup Jung;Ratan V. Bhat;Gregory M. Preston;William B. Guggino

  • Oxidative stress induces apoptosis in embryonic cortical neurons.

    Rajiv R. Ratan;Timothy H. Murphy;Jay M. Baraban

  • Solubilization, purification, and characterization of an inositol trisphosphate receptor.

    Surachai Supattapone;P. F. Worley;J. M. Baraban;S. H. Snyder

  • Characterization of inositol trisphosphate receptor binding in brain. Regulation by pH and calcium.

    P. F. Worley;J. M. Baraban;Surachai Supattapone;V. S. Wilson

  • Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists

    J.M. Baraban;G.K. Aghajanian

  • L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes.

    Timothy H. Murphy;Paul F. Worley;Jay M. Baraban

  • The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience

    Kevin J. O'Donovan;Warren G. Tourtellotte;Jeffrey Millbrandt;Jay M. Baraban

  • Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

    Akiko Hayashi-Takagi;Manabu Takaki;Nick Graziane;Saurav Seshadri

  • Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin.

    Khalequz Zaman;Hoon Ryu;David Hall;Kevin O'Donovan

  • Convulsant-induced increase in transcription factor messenger RNAs in rat brain

    David W. Saffen;Andrew J. Cole;Paul F. Worley;Barbara A. Christy

  • Protein kinase C regulates ionic conductance in hippocampal pyramidal neurons: electrophysiological effects of phorbol esters

    Jay M. Baraban;Solomon H. Snyder;Bradley E. Alger

  • Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement

    PF Worley;RV Bhat;JM Baraban;CA Erickson

  • Heterogeneous localization of protein kinase C in rat brain: autoradiographic analysis of phorbol ester receptor binding.

    PF Worley;JM Baraban;SH Snyder

  • Constitutive expression of zif268 in neocortex is regulated by synaptic activity.

    Paul F. Worley;Barbara A. Christy;Yusaku Nakabeppu;Ratan V. Bhat

  • Noradrenergic innervation of serotonergic neurons in the dorsal raphe: demonstration by electron microscopic autoradiography.

    J.M. Baraban;G.K. Aghajanian

  • Inositol trisphosphate receptor localization in brain: variable stoichiometry with protein kinase C.

    Paul F. Worley;Jay M. Baraban;Jennifer S. Colvin;Solomon H. Snyder

  • Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

    Rajiv R. Ratan;Timothy H. Murphy;Jay M. Baraban

  • Serotonergic and non-serotonergic neurons of the dorsal raphe: reciprocal changes in firing induced by peripheral nerve stimulation.

    G.K. Aghajanian;R.Y. Wang;J. Baraban

  • Noradrenergic agonists and antagonists: effects on conditioned fear as measured by the potentiated startle paradigm.

    Michael Davis;D. Eugene Redmond;Jay M. Baraban

Frequent Co-Authors

Paul F. Worley
Paul F. Worley Johns Hopkins University School of Medicine
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Timothy H. Murphy
Timothy H. Murphy University of British Columbia
Andrew J. Cole
Andrew J. Cole Harvard University
Rajiv R. Ratan
Rajiv R. Ratan Cornell University
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Peter C. Holland
Peter C. Holland Johns Hopkins University
George K. Aghajanian
George K. Aghajanian Yale University
Ted Abel
Ted Abel University of Iowa
Akira Sawa
Akira Sawa Johns Hopkins University

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