World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
24289
World Ranking
4273
National Ranking
2088

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2011 - Fellow of Alfred P. Sloan Foundation

Overview

Alan Saghatelian is affiliated with the Salk Institute for Biological Studies in the United States. Their research spans several fields within biochemistry, genetics, and molecular biology, with significant contributions also to medicine.

Their work primarily focuses on subjects such as RNA and protein synthesis mechanisms, adipose tissue and metabolism, RNA modifications and cancer, diet and metabolism studies, ubiquitin and proteasome pathways, RNA research and splicing, and genomics and phylogenetic studies.

Key subfields of study include molecular biology, physiology, cell biology, cancer research, and endocrinology, diabetes, and metabolism.

Alan Saghatelian has collaborated frequently with several researchers, including Antônio F. M. Pinto, Joan Vaughan, Cynthia J. Donaldson, Jolene K. Diedrich, and Eduardo Vieira de Souza.

Their research has been published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature, Cell Metabolism, and the Proceedings of the National Academy of Sciences.

Significant recent papers include:

  • Serine restriction alters sphingolipid diversity to constrain tumour growth, 2020, Nature
  • Standardized annotation of translated open reading frames, 2022, Nature Biotechnology
  • Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes, 2022, Cell
  • ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids, 2022, Nature
  • Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis, 2020, Nature Biotechnology

Alan Saghatelian has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2020 and a Fellow of the Alfred P. Sloan Foundation in 2011.

Best Publications

  • How many human proteoforms are there

    Ruedi Aebersold;Jeffrey N. Agar;I. Jonathan Amster;Mark S. Baker

  • Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects

    Mark M. Yore;Ismail Syed;Pedro M. Moraes-Vieira;Tejia Zhang

  • Peptidomic discovery of short open reading frame–encoded peptides in human cells

    Sarah A Slavoff;Andrew J Mitchell;Adam G Schwaid;Moran N Cabili;Moran N Cabili

  • The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

    Randall M. Chin;Xudong Fu;Melody Y. Pai;Laurent Vergnes

  • Toddler: an embryonic signal that promotes cell movement via Apelin receptors.

    Andrea Pauli;Megan L. Norris;Eivind Valen;Guo-Liang Chew

  • Identification of protein pheromones that promote aggressive behaviour

    Pablo Chamero;Tobias F. Marton;Darren W. Logan;Kelly Flanagan

  • mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide

    Akinobu Matsumoto;Alessandra Pasut;Masaki Matsumoto;Riu Yamashita

  • Activity-based probes for the proteomic profiling of metalloproteases

    Alan Saghatelian;Nadim Jessani;Arul Joseph;Mark Humphrey

  • Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

    Robert U Svensson;Seth J Parker;Lillian J Eichner;Matthew J Kolar

  • Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids.

    Donmienne Leung;Alan Saghatelian;Gabriel M. Simon;Benjamin F. Cravatt

  • Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism.

    Amir Zarrinpar;Amandine Chaix;Zhenjiang Z. Xu;Max W. Chang

  • Reversible Inhibitors of Fatty Acid Amide Hydrolase That Promote Analgesia: Evidence for an Unprecedented Combination of Potency and Selectivity

    Aron H. Lichtman;Donmienne Leung;Christopher C. Shelton;Alan Saghatelian

  • Assignment of endogenous substrates to enzymes by global metabolite profiling.

    Alan Saghatelian;Sunia A. Trauger;Elizabeth J. Want;Edward G. Hawkins

  • Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.

    Peiwen Chen;Hao Zuo;Hu Xiong;Matthew J. Kolar

  • Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

    Jessica J. Howell;Kristina Hellberg;Marc Turner;George Talbott

  • A chiroselective peptide replicator

    Alan Saghatelian;Yohei Yokobayashi;Kathy Soltani;M. Reza Ghadiri

  • Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.

    Gabriele Sulli;Amy Rommel;Xiaojie Wang;Matthew J. Kolar

  • Desorption/Ionization on Silicon Nanowires

    E. P. Go;J. V. Apon;G. Luo;A. Saghatelian

  • DNA-based photonic logic gates: AND, NAND, and INHIBIT.

    Alan Saghatelian;Nicolas H. Völcker;Kevin M. Guckian;Victor S.-Y. Lin

  • Defining the metabolome: size, flux, and regulation.

    Nicola Zamboni;Alan Saghatelian;Gary J. Patti

Frequent Co-Authors

Benjamin F. Cravatt
Benjamin F. Cravatt Scripps Research Institute
Barbara B. Kahn
Barbara B. Kahn Beth Israel Deaconess Medical Center
M. Reza Ghadiri
M. Reza Ghadiri Scripps Research Institute
Benjamin G. Neel
Benjamin G. Neel New York University Langone Medical Center
Satchidananda Panda
Satchidananda Panda Salk Institute for Biological Studies
Christopher Benner
Christopher Benner University of California, San Diego
John R. Yates
John R. Yates Scripps Research Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to a variety of related online degrees and dynamic career opportunities. For students interested in the intersection of science and management, pursuing the cheapest online MBA healthcare management programs is a practical option. These online programs are both accessible and affordable, preparing graduates for leadership roles in healthcare and research sectors.

Another popular direction is a career in medical coding or billing, especially for those interested in healthcare but preferring a non-clinical role. Understanding the differences between ccs vs cpc certification is crucial, as each certification path suits different career goals and can impact salary potential.

If you’re considering this field, you may also want to explore what a medical.coder salary looks like, and the overall career outlook. Generally, the job outlook for medical billing and coding remains strong, offering flexibility, steady income, and room for advancement within the healthcare industry.

Best Scientists Citing Alan Saghatelian

Trending Scientists

Recently Published Articles