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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
10675
World Ranking
16115
National Ranking
6678

Overview

Sherry Niessen is affiliated with Pfizer in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work primarily focuses on molecular biology and oncology, with additional research spanning pulmonary and respiratory medicine, cell biology, and organic chemistry.

Their research topics cover a diverse range of cancer-related and biochemical areas, including:

  • Advanced Breast Cancer Therapies
  • Click Chemistry and Applications
  • Microtubule and Mitosis Dynamics
  • Chemical Synthesis and Analysis
  • Lung Cancer Research Studies
  • Cancer-related Molecular Pathways
  • Protein Degradation and Inhibitors

Notable recent publications by Sherry Niessen include:

  • "Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor" (2021), published in Cancer Cell
  • "Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity" (2023), published in Cell
  • "Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer" (2021), published in Journal of Medicinal Chemistry
  • "Reversible lysine-targeted probes reveal residence time-based kinase selectivity" (2022), published in Nature Chemical Biology
  • "Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1" (2020), published in Journal of Biological Chemistry

Frequent co-authors collaborating with Sherry Niessen include:

  • John D. Lapek
  • Todd VanArsdale
  • Nichol Miller
  • Asako Nagata
  • Martha A. Ornelas

Their work has been published multiple times in venues such as Cancer Research and UNC Libraries, each featuring four papers. Other frequent publication venues include Nature Chemical Biology, Cancer Cell, and Cell.

Sherry Niessen contributes primarily to the fields of biochemistry, genetics, and molecular biology, with a significant emphasis on medicine. Their subfields of study emphasize molecular biology and oncology, reflecting a focus on understanding cellular mechanisms and cancer biology through advanced chemical and biological approaches.

Best Publications

  • Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

    Daniel K. Nomura;Jonathan Z. Long;Sherry Niessen;Heather S. Hoover

  • The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.

    Robert A. Screaton;Michael D. Conkright;Yoshiko Katoh;Jennifer L. Best

  • A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

    Iain M. Cheeseman;Sherry Niessen;Scott Anderson;Francie Hyndman

  • A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

    Bryan R Lanning;Landon R Whitby;Melissa M Dix;John Douhan

  • TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

    Ling Qi;Jose E. Heredia;Judith Y. Altarejos;Robert Screaton

  • Proteomic profiling of metalloprotease activities with cocktails of active-site probes

    Stephan A Sieber;Sherry Niessen;Heather S Hoover;Benjamin F Cravatt

  • Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

    Daniel A. Bachovchin;Tianyang Ji;Weiwei Li;Gabriel M. Simon

  • Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

    Andrew J. Holland;Weijie Lan;Sherry Niessen;Heather Hoover

  • A streamlined platform for high-content functional proteomics of primary human specimens

    Nadim Jessani;Nadim Jessani;Sherry Niessen;BinQing Q Wei;Monica Nicolau

  • Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer

    Daniel K. Nomura;Donald P. Lombardi;Jae Won Chang;Sherry Niessen

  • Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors

    Alexander Adibekian;Brent R. Martin;Chu Wang;Ku Lung Hsu

  • A Hormone-Dependent Module Regulating Energy Balance

    Biao Wang;Noel Moya;Sherry Niessen;Heather Hoover

  • A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

    Rebecca A. Green;Huey Ling Kao;Anjon Audhya;Swathi Arur

  • An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.

    Kyle P. Chiang;Sherry Niessen;Alan Saghatelian;Benjamin F. Cravatt

  • Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo

    Nadim Jessani;Mark Humphrey;W. Hayes McDonald;Sherry Niessen

  • Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

    Kerstin H. Richau;Farnusch Kaschani;Martijn Verdoes;Twinkal C. Pansuriya

  • Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates.

    Jae Won Chang;Micah J. Niphakis;Kenneth M. Lum;Armand B. Cognetta

  • Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling.

    Heather S. Hoover;Jacqueline L. Blankman;Sherry Niessen;Benjamin F. Cravatt

  • Diversity of Serine Hydrolase Activities of Unchallenged and Botrytis-infected Arabidopsis thaliana

    Farnusch Kaschani;Christian Gu;Sherry Niessen;Heather Hoover

  • Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase.

    Michelle M. Shimogawa;Beth Graczyk;Melissa K. Gardner;Susan E. Francis

Frequent Co-Authors

Benjamin F. Cravatt
Benjamin F. Cravatt Scripps Research Institute
John R. Yates
John R. Yates Scripps Research Institute
Renier A. L. van der Hoorn
Renier A. L. van der Hoorn University of Oxford
Ülo Langel
Ülo Langel Stockholm University
Arshad Desai
Arshad Desai University of California, San Diego
Karen Oegema
Karen Oegema University of California, San Diego
Markus Kaiser
Markus Kaiser University of Duisburg-Essen
Marc Montminy
Marc Montminy Salk Institute for Biological Studies
Michael D. Burkart
Michael D. Burkart University of California, San Diego

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