Shigetomo Fukuhara

Overview

Best Publications

• Cbl-b regulates the CD28 dependence of T-cell activation

  Yungping J. Chiang;Hemanta K. Kole;Karen Brown;Mayumi Naramura

  719
  Citations

• Cyclic AMP Potentiates Vascular Endothelial Cadherin-Mediated Cell-Cell Contact To Enhance Endothelial Barrier Function through an Epac-Rap1 Signaling Pathway

  Shigetomo Fukuhara;Atsuko Sakurai;Hideto Sano;Akiko Yamagishi

  488
  Citations

• A Novel PDZ Domain Containing Guanine Nucleotide Exchange Factor Links Heterotrimeric G Proteins to Rho

  Shigetomo Fukuhara;Cristina Murga;Muriel Zohar;Tadashi Igishi

  488
  Citations

• Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1

  Shigetomo Fukuhara;Keisuke Sako;Takashi Minami;Kazuomi Noda

  447
  Citations

• Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance

  Mitsuhisa Tabata;Tsuyoshi Kadomatsu;Shigetomo Fukuhara;Keishi Miyata

  417
  Citations

• The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

  Shigetomo Fukuhara;Szandor Simmons;Shunsuke Kawamura;Asuka Inoue

  342
  Citations

• Identification of Multiple Novel Epididymis-Specific β-Defensin Isoforms in Humans and Mice

  Yasuhiro Yamaguchi;Takahide Nagase;Ryosuke Makita;Shigetomo Fukuhara

  333
  Citations

• Leukemia‐associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G12 family to Rho

  Shigetomo Fukuhara;Hiroki Chikumi;J.Silvio Gutkind

  308
  Citations

• RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

  Shigetomo Fukuhara;Shigetomo Fukuhara;Hiroki Chikumi;J Silvio Gutkind

  289
  Citations

• Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance

  Hiroyuki Nakajima;Kimiko Yamamoto;Sobhika Agarwala;Kenta Terai

  275
  Citations

• The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome

  Naomasa Makita;Elijah Behr;Wataru Shimizu;Minoru Horie

  262
  Citations

• A Novel Role for Phosphatidylinositol 3-Kinase β in Signaling from G Protein-coupled Receptors to Akt

  Cristina Murga;Shigetomo Fukuhara;J.Silvio Gutkind

  247
  Citations

• Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis.

  Benoît Vanhollebeke;Oliver A Oa Stone;Naguissa Bostaille;Chris C Cho

  237
  Citations

• Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis.

  Shigetomo Fukuhara;Keisuke Sako;Kazuomi Noda;Jianghui Zhang

  235
  Citations

• Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation

  Noritaka Yasuda;Shin-ichiro Miura;Hiroshi Akazawa;Toshimasa Tanaka

  211
  Citations

• Regulation of G Protein-linked Guanine Nucleotide Exchange Factors for Rho, PDZ-RhoGEF, and LARG by Tyrosine Phosphorylation EVIDENCE OF A ROLE FOR FOCAL ADHESION KINASE

  Hiroki Chikumi;Shigetomo Fukuhara;J. Silvio Gutkind

  208
  Citations

• Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish

  Koji Ando;Shigetomo Fukuhara;Nanae Izumi;Hiroyuki Nakajima

  205
  Citations

• Vascular Endothelial-Cadherin Stabilizes at Cell-Cell Junctions by Anchoring to Circumferential Actin Bundles through α- and β-Catenins in Cyclic AMP-Epac-Rap1 Signal-activated Endothelial Cells

  Kazuomi Noda;Jianghui Zhang;Shigetomo Fukuhara;Satoshi Kunimoto

  191
  Citations

• MAGI-1 Is Required for Rap1 Activation upon Cell-Cell Contact and for Enhancement of Vascular Endothelial Cadherin-mediated Cell Adhesion

  Atsuko Sakurai;Shigetomo Fukuhara;Akiko Yamagishi;Keisuke Sako

  182
  Citations

• Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

  Koji Ando;Shigetomo Fukuhara;Takahiro Moriya;Yutaro Obara;Yutaro Obara

  181
  Citations