What is he best known for?
The fields of study he is best known for:
- Gene
- Signal transduction
- Genetics
His scientific interests lie mostly in Cell biology, Signal transduction, G protein-coupled receptor, Genetics and G protein.
He is interested in Protein kinase B, which is a branch of Cell biology.
His Signal transduction research includes elements of Cadherin, Forskolin, Protein kinase A and Prostacyclin.
His studies in G protein-coupled receptor integrate themes in fields like Biophysics, Inverse agonist and Transmembrane protein.
His G protein research is multidisciplinary, relying on both Protein subunit, PDZ domain, Pleckstrin homology domain and Kinase activity.
Shigetomo Fukuhara interconnects Guanine nucleotide exchange factor, Cell surface receptor and Adenylyl cyclase in the investigation of issues within Heterotrimeric G protein.
His most cited work include:
- Cbl-b regulates the CD28 dependence of T-cell activation (524 citations)
- A Novel PDZ Domain Containing Guanine Nucleotide Exchange Factor Links Heterotrimeric G Proteins to Rho (358 citations)
- Cyclic AMP Potentiates Vascular Endothelial Cadherin-Mediated Cell-Cell Contact To Enhance Endothelial Barrier Function through an Epac-Rap1 Signaling Pathway (345 citations)
What are the main themes of his work throughout his whole career to date?
Shigetomo Fukuhara mostly deals with Cell biology, Angiogenesis, Signal transduction, Zebrafish and Internal medicine.
His research in Cell biology intersects with topics in Cadherin, Cell adhesion and Actin cytoskeleton.
His research on Angiogenesis also deals with topics like
- Pathology which intersects with area such as Wound healing,
- Protein kinase B together with MAPK/ERK pathway.
His study on Signal transduction also encompasses disciplines like
- Protein subunit which connect with Kinase activity and Adenylyl cyclase,
- Extracellular matrix and Angiopoietin receptor most often made with reference to Angiopoietin-1.
As part of the same scientific family, Shigetomo Fukuhara usually focuses on Internal medicine, concentrating on Endocrinology and intersecting with Transcription factor.
The G protein-coupled receptor study combines topics in areas such as Heterotrimeric G protein, G protein and Cell surface receptor.
He most often published in these fields:
- Cell biology (78.72%)
- Angiogenesis (24.47%)
- Signal transduction (25.53%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (78.72%)
- Zebrafish (20.21%)
- Angiogenesis (24.47%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cell biology, Zebrafish, Angiogenesis, Mural cell and Pathology.
All of his Cell biology and Signal transduction and Stem cell investigations are sub-components of the entire Cell biology study.
His work deals with themes such as Psychological repression, Haematopoiesis and Mutation, which intersect with Signal transduction.
The various areas that Shigetomo Fukuhara examines in his Zebrafish study include Pericyte, Live cell imaging, Lymphatic system and Mesoderm.
His biological study spans a wide range of topics, including Protein kinase B, Chemotaxis, Motility and MAPK/ERK pathway.
His work carried out in the field of Pathology brings together such families of science as Wound healing, Cutaneous wound, Vessel regression and Vascular endothelial growth factor.
Between 2017 and 2021, his most popular works were:
- Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling (16 citations)
- Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. (10 citations)
- Live imaging of angiogenesis during cutaneous wound healing in adult zebrafish (10 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Signal transduction
- Genetics
Shigetomo Fukuhara mainly focuses on Zebrafish, Cell biology, Live cell imaging, Notch signaling pathway and Cutaneous wound.
His Zebrafish study combines topics from a wide range of disciplines, such as Mesenchyme, Mural cell, Developmental biology, PDGFRB and Mesoderm.
His studies deal with areas such as Integrin and Somite as well as Cell biology.
His Live cell imaging study combines topics in areas such as Ultrastructure, Circulatory system, Lymphatic system, Morphogenesis and Interstitial fluid.
His Notch signaling pathway research incorporates elements of Pericyte, Hematopoietic stem cell, Hemogenic endothelium, Cell adhesion and Stem cell.
His Cutaneous wound research incorporates themes from Vessel regression, Angiogenesis, Vascular endothelial growth factor and Normal skin, Pathology.
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