What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Enzyme
His main research concerns Immunology, Molecular biology, Peptide sequence, T cell and Antigen.
Immunology connects with themes related to CD40 in his study.
His biological study spans a wide range of topics, including Cytotoxic T cell, Interleukin 12, Interleukin 21 and Downregulation and upregulation.
His work deals with themes such as Binding site and Peptide, which intersect with Peptide sequence.
His research integrates issues of T lymphocyte, Antibody, CCL1 and Monoclonal in his study of T cell.
The Antigen study combines topics in areas such as Clone and Allergy.
His most cited work include:
- Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells (763 citations)
- Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices (707 citations)
- Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene. (587 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Immunology, T cell, Antigen, Epitope and Molecular biology.
His T cell study combines topics in areas such as T lymphocyte, CD8, Antibody and Virology.
His study in Major histocompatibility complex and Human leukocyte antigen are all subfields of Antigen.
His work in Molecular biology covers topics such as Interleukin 21 which are related to areas like IL-2 receptor and CD40.
Francesco Sinigaglia interconnects CC chemokine receptors and CXCL16 in the investigation of issues within CCL5.
In his study, Peptide is strongly linked to Peptide binding, which falls under the umbrella field of MHC class II.
He most often published in these fields:
- Immunology (39.42%)
- T cell (29.93%)
- Antigen (21.17%)
What were the highlights of his more recent work (between 2000-2012)?
- Immunology (39.42%)
- T cell (29.93%)
- Cell biology (10.22%)
In recent papers he was focusing on the following fields of study:
Francesco Sinigaglia mainly investigates Immunology, T cell, Cell biology, Chemokine receptor and Chemokine.
His Immunology study frequently links to adjacent areas such as Receptor.
His T cell research includes themes of Epitope, Antigen and Virology.
As part of the same scientific family, Francesco Sinigaglia usually focuses on Antigen-presenting cell, concentrating on CCL5 and intersecting with CXCL16.
His CC chemokine receptors study combines topics from a wide range of disciplines, such as CCL17, CCL13 and CCL1.
His research investigates the connection between Interleukin 3 and topics such as Interleukin 12 that intersect with issues in Molecular biology.
Between 2000 and 2012, his most popular works were:
- Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells (763 citations)
- The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics (410 citations)
- Increased Expression of the Chemokine Receptor CXCR3 and Its Ligand CXCL10 in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease (318 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Enzyme
Francesco Sinigaglia spends much of his time researching Immunology, Chemokine receptor, Chemokine, CC chemokine receptors and Receptor.
His work on Immunology deals in particular with T cell, CXCL10, Interleukin 4 and Proinflammatory cytokine.
His Chemokine receptor study incorporates themes from Autoimmunity and Disease.
His studies deal with areas such as Tumor necrosis factor alpha, Interferon gamma and CD40 as well as Chemokine.
His CC chemokine receptors research is multidisciplinary, relying on both CCL17, CCL13, CCL5 and CCL1.
The concepts of his CCL17 study are interwoven with issues in Cytotoxic T cell, Antigen-presenting cell, CCL28, CXCL16 and Chemokine receptor CCR5.
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