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Overview

Lars Rogge is affiliated with the Institut Pasteur in France and conducts research primarily in the fields of Immunology and Microbiology, with significant contributions to Medicine. Their work often intersects several subfields including Immunology, Rheumatology, Genetics, Molecular Biology, and Hematology.

The scientist's research focuses on key topics such as:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Psoriasis: Treatment and Pathogenesis
  • Spondyloarthritis Studies and Treatments
  • IL-33, ST2, and ILC Pathways
  • Inflammatory Bowel Disease
  • Autoimmune and Inflammatory Disorders Research

Lars Rogge has published notable recent papers including:

  • "Smoking changes adaptive immunity with persistent effects" (2024, Nature)
  • "The immune factors driving DNA methylation variation in human blood" (2022, Nature Communications)
  • "Characterization of Blood Mucosal-Associated Invariant T Cells in Patients With Axial Spondyloarthritis and of Resident Mucosal-Associated Invariant T Cells From the Axial Entheses of Non-Axial Spondyloarthritis Control Patients" (2022, Arthritis & Rheumatology)
  • "Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes" (2022, Genome Medicine)
  • "Cellular and molecular profiling of T-cell subsets at the onset of human acute GVHD" (2020, Blood Advances)

Their collaborative network includes frequent co-authors such as Darragh Duffy, Lluís Quintana-Murci, Elisabetta Bianchi, Étienne Patin, and Milena Hasan.

Among the venues where Lars Rogge commonly publishes are Annals of the Rheumatic Diseases, Arthritis & Rheumatology, iScience, Frontiers in Immunology, and Journal of Cystic Fibrosis. The volume of publications in these venues indicates a focused presence in journals related to rheumatic diseases and immunology.

Best Publications

  • Selective Expression of an Interleukin-12 Receptor Component by Human T Helper 1 Cells

    Lars Rogge;Luisella Barberis-Maino;Mauro Biffi;Nadia Passini

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127.

    Christian A J Vosshenrich;Marcos E García-Ojeda;Sandrine I Samson-Villéger;Valerie Pasqualetto

  • Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

    Ai Ing Lim;Ai Ing Lim;Ai Ing Lim;Yan Li;Yan Li;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Ralph Stadhouders

  • The Role of Stat4 in Species-Specific Regulation of Th Cell Development by Type I IFNs

    Lars Rogge;Daniele D’Ambrosio;Mauro Biffi;Giuseppe Penna

  • Transcript imaging of the development of human T helper cells using oligonucleotide arrays

    Lars Rogge;Elisabetta Bianchi;Mauro Biffi;Elisa Bono

  • Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

    Etienne Patin;Milena Hasan;Jacob Bergstedt;Vincent Rouilly

  • IL-12 drives functional plasticity of human group 2 innate lymphoid cells

    Ai Ing Lim;Ai Ing Lim;Silvia Menegatti;Jacinta Bustamante;Lionel Le Bourhis

  • Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity.

    E. Bonifacio;S. Genovese;S. Braghi;E. Bazzigaluppi

  • Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli.

    Darragh Duffy;Darragh Duffy;Vincent Rouilly;Valentina Libri;Milena Hasan

  • Antibodies to the IL-12 receptor beta 2 chain mark human Th1 but not Th2 cells in vitro and in vivo.

    Lars Rogge;Alberto Papi;David H. Presky;Mauro Biffi

  • Regulation of the IL‐12/IL‐12R axis: a critical step in T‐helper cell differentiation and effector function

    Francesco Sinigaglia;Daniele D'Ambrosio;Poola Panina-Bordignon;Lars Rogge

  • Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

    Petar Scepanovic;Petar Scepanovic;Cécile Alanio;Christian Hammer;Christian Hammer;Christian Hammer;Flavia Hodel;Flavia Hodel

  • Proinflammatory Environment Dictates the IL-17–Producing Capacity of Human Invariant NKT Cells

    Lúcia Moreira-Teixeira;Mariana Resende;Maryaline Coffre;Odile Devergne

  • The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.

    N Passini;J D Larigan;S Genovese;E Appella

  • Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites.

    David Michonneau;Eleonora Latis;Emmanuel Curis;Laetitia Dubouchet

  • Interleukin-12 induces expression of interferon regulatory factor-1 via signal transducer and activator of transcription-4 in human T helper type 1 cells.

    Eliana M. Coccia;Nadia Passini;Angela Battistini;Carlo Pini

  • Upregulation of Integrin ∝6/β1 and Chemokine Receptor CCR1 by Interleukin-12 Promotes the Migration of Human Type 1 Helper T Cells

    Lucia Colantonio;Andrea Iellem;Barbara Clissi;Ruggero Pardi

  • Down-Modulation of Responses to Type I IFN Upon T Cell Activation

    Elisabetta Dondi;Lars Rogge;Georges Lutfalla;Gilles Uzé

  • The COP9 signalosome regulates Skp2 levels and proliferation of human cells.

    Simona Denti;Maria Elena Fernandez-Sanchez;Lars Rogge;Elisabetta Bianchi

Frequent Co-Authors

Francesco Sinigaglia
Francesco Sinigaglia Dompé (Italy)
James P. Di Santo
James P. Di Santo Institut Pasteur
Darragh Duffy
Darragh Duffy Institut Pasteur
Lluis Quintana-Murci
Lluis Quintana-Murci Institut Pasteur
Sandra Pellegrini
Sandra Pellegrini Institut Pasteur
Etienne Patin
Etienne Patin Institut Pasteur
Jérôme Larghero
Jérôme Larghero Université Paris Cité
Jacques Fellay
Jacques Fellay École Polytechnique Fédérale de Lausanne
Elisabetta Bianchi
Elisabetta Bianchi Institut Pasteur

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