Gianni Garotta

Overview

Best Publications

• INTERLEUKIN-12 IS REQUIRED FOR INTERFERON-GAMMA PRODUCTION AND LETHALITY IN LIPOPOLYSACCHARIDE-INDUCED SHOCK IN MICE

  Maria Wysocka;Marek Kubin;Leda Q. Vieira;Leda Q. Vieira;Laurence Ozmen;Laurence Ozmen

  581
  Citations

• System for High-Level Production in Escherichia coli and Rapid Purification of Recombinant Proteins: Application to Epitope Mapping, Preparation of Antibodies, and Structure—Function Analysis

  Dietrich Stüber;Hugues Matile;Gianni Garotta

  359
  Citations

• Molecular and Functional Characterization of Two Novel Human C-C Chemokines as Inhibitors of Two Distinct Classes of Myeloid Progenitors

  Vikram P. Patel;Brent L. Kreider;Yuling Li;Haodong Li

  344
  Citations

• Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction.

  L Ozmen;M Pericin;J Hakimi;R A Chizzonite

  328
  Citations

• Biphasic effect of interferon-gamma in murine collagen-induced arthritis.

  Marie-Christophe Boissier;Gilles Chiocchia;Natacha Bessis;Julia Hajnal

  305
  Citations

• Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon-gamma receptor inhibits the onset of glomerulonephritis.

  Laurence Ozmen;Danièle Roman;Michael Fountoulakis;Georges Schmid

  278
  Citations

• Isolation and characterization of Ni-specific T cell clones from patients with Ni-contact dermatitis.

  F Sinigaglia;D Scheidegger;G Garotta;R Scheper

  255
  Citations

• Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor.

  K. Igarashi;G. Garotta;L. Ozmen;A. Ziemiecki

  254
  Citations

• Distribution of interferon-γ receptor in human tissues

  Guido Valente;Laurence Ozmen;Francesco Novelli;Massimo Geuna

  251
  Citations

• Role of interferon-gamma in mediating the antitumor efficacy of interleukin-12

  Michael J. Brunda;Leopoldo Luistro;Jill A. Hendrzak;Michael Fountoulakis

  245
  Citations

• The interferon gamma (IFN-γ) receptor: a paradigm for the multichain cytokine receptor

  Sidney Pestka;Serguei V. Kotenko;Geetha Muthukumaran;Lara S. Izotova

  237
  Citations

• Interaction Between the Components of the Interferon Gamma Receptor Complex

  Serguei V. Kotenko;Lara S. Izotova;Brian P. Pollack;Thomas M. Mariano

  208
  Citations

• The Jak Kinases Differentially Associate with the α and β (Accessory Factor) Chains of the Interferon γ Receptor to Form a Functional Receptor Unit Capable of Activating STAT Transcription Factors

  Minoru Sakatsume;Ken-ichi Igarashi;Karen D. Winestock;Gianni Garotta

  204
  Citations

• Baculovirus Stimulates Antiviral Effects in Mammalian Cells

  Ann M. Gronowski;David M. Hilbert;Kathleen C. F. Sheehan;Gianni Garotta

  182
  Citations

• Tumor rejection and immune memory elicited by locally released LEC chemokine are associated with an impressive recruitment of APCs, lymphocytes, and granulocytes.

  Mirella Giovarelli;Paola Cappello;Guido Forni;Theodora Salcedo

  149
  Citations

• The effects of a monoclonal antibody to interferon‐γ on experimental autoimmune thyroiditis (EAT): prevention of disease and decrease of EAT‐specific T cells

  Haiwen Tang;Karine Mignon-Godefroy;Pier Luigi Meroni;Gianni Garotta

  145
  Citations

• Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor.

  Francesco Novelli;Paola Bernabei;Laurence Ozmen;Laura Rigamonti

  141
  Citations

• Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.

  DJ Thiel;M-H le Du;RL Walter;A D’Arcy

  137
  Citations

• IFN-gamma involvement in the severity of gram-negative infections in mice.

  Unknown

  115
  Citations

• Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis.

  F Novelli;F Di Pierro;P Francia di Celle;S Bertini

  110
  Citations

• Stoichiometry of interaction between interferon γ and its receptor

  Michael Fountoulakis;Martin Zulauf;Ariel Lustig;Gianni Garotta

  108
  Citations

• Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices.

  Marina Pizzi;Ilenia Sarnico;Flora Boroni;Marina Benarese

  108
  Citations