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Medicine

D-Index
84
Citations
26857
World Ranking
15054
National Ranking
1389

Overview

David J. Harrison is affiliated with the University of St Andrews in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Cancer Research, and Radiology, Nuclear Medicine and Imaging.

Their work covers a range of topics including Radiomics and Machine Learning in Medical Imaging, Cancer Genomics and Diagnostics, AI in cancer detection, Renal cell carcinoma treatment, Cancer Immunotherapy and Biomarkers, Colorectal Cancer Treatments and Studies, and RNA modifications and cancer.

Frequent publication venues for their research include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Cancers
  • Nature

Notable recent papers authored or co-authored by David J. Harrison include:

  • The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer, 2022, Nature
  • Spatial immune profiling of the colorectal tumor microenvironment predicts good outcome in stage II patients, 2020, npj Digital Medicine
  • RAMPART: A phase III multi-arm multi-stage trial of adjuvant checkpoint inhibitors in patients with resected primary renal cell carcinoma (RCC) at high or intermediate risk of relapse, 2021, Contemporary Clinical Trials
  • Tissue-specific tolerance in fatal Covid-19, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial, 2021, Clinical Cancer Research

Frequent collaborators working with David J. Harrison include:

  • In Hwa Um
  • Ognjen Arandjelović
  • Alison L. Dickson
  • Oliver J. Read
  • Mustafa Elshani

Best Publications

  • Thymocyte apoptosis induced by p53-dependent and independent pathways

    A. R. Clarke;C. A. Purdie;C. A. Purdie;D. J. Harrison;R. G. Morris

  • The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

    Juliette Janson;Richard H. Ashley;David Harrison;Susan McIntyre

  • Orphan CpG islands identify numerous conserved promoters in the mammalian genome

    Robert S. Illingworth;Ulrike Gruenewald-Schneider;Shaun Webb;Alastair R. W. Kerr

  • Update of the International Banff Schema for Liver Allograft Rejection: working recommendations for the histopathologic staging and reporting of chronic rejection. An International Panel.

    Anthony Demetris;David Adams;Chris Bellamy;Karin Blakolmer

  • Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema

    Christopher Ad Smith;David J Harrison

  • Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

    Antonis Koussounadis;Simon Langdon;In Hwa Um;David James Harrison

  • High-frequency developmental abnormalities in p53-deficient mice

    Jane F. Armstrong;Matthew H. Kaufman;David J. Harrison;Alan R. Clarke

  • Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

    Colm E. Nestor;Raffaele Ottaviano;James Reddington;Duncan Sproul

  • Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production.

    Sergey I. Dikalov;Anna E. Dikalova;Alfiya T. Bikineyeva;Harald H.H.W. Schmidt

  • Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

    C A Purdie;D J Harrison;A Peter;L Dobbie

  • Cell death in health and disease: the biology and regulation of apoptosis

    Christopher Bellamy;R D Malcomson;David J Harrison;A H Wyllie

  • Muir's textbook of pathology

    David Levison;Robin Reid;Alistair D Burt;David J. Harrison

  • Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion

    Philip N Newsome;Ingolfur Johannessen;Shelagh Boyle;Evangelos Dalakas

  • Mice with DNA repair gene ( ERCC-1 ) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

    Jim McWhir;Jim Selfridge;David J. Harrison;Shoshana Squires

  • Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

    Davina J Hensman Moss;Antonio F Pardiñas;Douglas Langbehn;Kitty Lo

  • WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis

    Jian-Kan Guo;Aswin Menke;Marie-Claire Gubler;Alan Richard Clarke

  • Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study

    Grant D. Stewart;Leander Van Neste;Philippe Delvenne;Paul Delrée

  • Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members.

    Tania O'connor;Linda S. Ireland;David J. Harrison;John D. Hayes

  • Tissue-specific Immunopathology in Fatal COVID-19.

    David A Dorward;Clark D Russell;In Hwa Um;Mustafa Elshani

  • WT1 is a key regulator of podocyte function

    Jian-Kan Guo;Aswin L Menke;Marie-Claire Gubler;Alan Clarke

Frequent Co-Authors

Simon P. Langdon
Simon P. Langdon University of Edinburgh
Thomas Powles
Thomas Powles Queen Mary University of London
Alan Richard Clarke
Alan Richard Clarke Cardiff University
John D. Hayes
John D. Hayes University of Dundee
Peter C. Hayes
Peter C. Hayes University of Edinburgh
Richard R. Meehan
Richard R. Meehan University of Edinburgh
Stephen B. Dunnett
Stephen B. Dunnett Cardiff University
Mark J. Arends
Mark J. Arends University of Edinburgh
Philip N. Newsome
Philip N. Newsome University of Birmingham
Sarah E. M. Howie
Sarah E. M. Howie University of Edinburgh

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