World's Best Scientists 2026 revealed!

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Immunology

D-Index
56
Citations
9799
World Ranking
3753
National Ranking
330

Overview

Sarah E. M. Howie is affiliated with the University of Edinburgh in the United Kingdom. Their research primarily falls within the field of Medicine, focusing on Surgery, Molecular Biology, Microbiology, Genetics, and Epidemiology.

The scientist's work covers several topics related to health and disease mechanisms. These include:

  • Gut microbiota and health
  • Helicobacter pylori-related gastroenterology studies
  • Orthopedic Infections and Treatments
  • Inflammatory Bowel Disease
  • Reproductive tract infections research
  • Preterm Birth and Chorioamnionitis
  • COVID-19 Impact on Reproduction

Their frequent coauthors, each collaborating on multiple publications, are:

  • Biljana Nikolić
  • Malcolm Alison
  • Claire E. Lewis
  • Joseph Boyle
  • Anne Cooke

Sarah E. M. Howie's research findings have been published in diverse academic venues, with a strong representation in the International Journal of Experimental Pathology. The frequent publication venues include:

  • International Journal of Experimental Pathology
  • Science Advances
  • Nature Communications
  • Cell Reports
  • Bone and Joint Research

Notable recent papers authored or coauthored by the scientist include:

  • "Prostaglandin E 2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells," published in 2021 in Science Advances
  • "Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice," published in 2020 in Nature Communications
  • "Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis," published in 2023 in Cell Reports
  • "Septic arthritis in an in vivo murine model induced by Staphylococcus aureus," published in 2022 in Bone and Joint Research
  • "The long-term time course of septic arthritis," published in 2024 in Bone & Joint Open

Best Publications

  • The role of infection in miscarriage

    Sevi Giakoumelou;Nick Wheelhouse;Kate Cuschieri;Gary Entrican

  • Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.

    Michael A Gibbons;Alison C MacKinnon;Prakash Ramachandran;Kevin Dhaliwal

  • In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes.

    G. J. Bellingan;H. Caldwell;S. E. M. Howie;I. Dransfield

  • Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

    Wan-Seob Cho;Rodger Duffin;Sarah E M Howie;Chris J Scotton

  • Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

    C A Purdie;D J Harrison;A Peter;L Dobbie

  • Metal Oxide Nanoparticles Induce Unique Inflammatory Footprints in the Lung: Important Implications for Nanoparticle Testing

    Wan-Seob Cho;Rodger Duffin;Craig A Poland;Sarah E M Howie

  • A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA).

    W. A. H. Wallace;E. A. Ramage;D. Lamb;S. E. M. Howie

  • Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4+CD25+Foxp3+ regulatory T cells

    Ingrid E. Dumitriu;Donald R. Dunbar;Sarah E. Howie;Tariq Sethi

  • Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

    Rodger Duffin;Richard A. O’Connor;Siobhan Crittenden;Thorsten Forster

  • Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes.

    Gareth A Stewart;Gerard F Hoyne;Sharon A Ahmad;Elizabeth Jarman

  • Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

    Damian J Mole;Scott P Webster;Iain Uings;Xiaozhong Zheng

  • Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1β in delirium after hip fracture.

    Eleanor Cape;Roanna J Hall;Roanna J Hall;Barbara C van Munster;Barbara C van Munster;Annick de Vries

  • Ultraviolet-Irradiated Urocanic Acid Suppresses Delayed-Type Hypersensitivity to Herpes Simplex Virus in Mice

    James A Ross;Sarah E M Howie;Mary Norval;Jean Maingay

  • The hedgehog signalling pathway in the gastrointestinal tract: implications for development, homeostasis, and disease.

    Charlie Lees;Charlie Lees;Sarah Howie;R. Balfour Sartor;Jack Satsangi

  • Exposure to Low-Dose Ultraviolet Radiation Suppresses Delayed-Type Hypersensitivity to Herpes Simplex Virus in Mice

    Sarah Howie;Mary Norval;Jean Maingay

  • An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade

    Lynda Vuong;Eleni Kouverianou;Claire M. Rooney;Brian J. McHugh

  • "Dirty little secrets"--endotoxin contamination of recombinant proteins.

    Sonia J. Wakelin;Ian Sabroe;Christopher D. Gregory;Ian R. Poxton

  • Sonic Hedgehog Signaling Modulates Activation of and Cytokine Production by Human Peripheral CD4+ T Cells

    Gareth A. Stewart;Jacqueline A. Lowrey;Sonia J. Wakelin;Sonia J. Wakelin;Paul M. Fitch;Paul M. Fitch

  • The role of megalin (LRP-2/Gp330) during development.

    Carolyn E Fisher;Sarah E M Howie

  • Resolution of Der p1-Induced Allergic Airway Inflammation Is Dependent on CD4+CD25+Foxp3+ Regulatory Cells

    Melanie D Leech;Robert A Benson;Annick De Vries;Paul M Fitch

  • Sonic Hedgehog Promotes Cell Cycle Progression in Activated Peripheral CD4+ T Lymphocytes

    Jacqueline A. Lowrey;Gareth A. Stewart;Susannah Lindey;Gerard F. Hoyne

Frequent Co-Authors

Mary Norval
Mary Norval University of Edinburgh
Stephen M. Anderton
Stephen M. Anderton University of Edinburgh
Adriano G. Rossi
Adriano G. Rossi University of Edinburgh
Jürgen Schwarze
Jürgen Schwarze University of Edinburgh
David J. Harrison
David J. Harrison University of St Andrews
Jonathan R. Lamb
Jonathan R. Lamb Imperial College London
William MacNee
William MacNee University of Edinburgh
Ian Dransfield
Ian Dransfield University of Edinburgh
Christopher Haslett
Christopher Haslett University of Edinburgh
Shuh Narumiya
Shuh Narumiya Kyoto University

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