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Molecular Biology

D-Index
41
Citations
5088
World Ranking
3063
National Ranking
80

Overview

Patrizia Lavia is affiliated with Sapienza University of Rome in Italy. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology and Cell Biology. Additional subfields include Plant Science, Epidemiology, and Organic Chemistry.

The scientist's work often centers on key topics such as:

  • Ubiquitin and proteasome pathways
  • Microtubule and mitosis dynamics
  • CRISPR and Genetic Engineering
  • Chromosomal and Genetic Variations
  • RNA Research and Splicing
  • RNA Interference and Gene Delivery
  • Autophagy in Disease and Therapy

Patrizia Lavia has authored several research papers published in a variety of venues. Notable publications include:

  • "Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity", 2021, Molecular Cell
  • "Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells", 2020, Cancer Letters
  • "Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells", 2022, Cancer Gene Therapy
  • "An Epigenetic LINE-1-Based Mechanism in Cancer", 2022, International Journal of Molecular Sciences
  • "RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo", 2022, European Journal of Medicinal Chemistry

Frequent publication venues for their work include:

  • Cells
  • Molecular Cell
  • Cancer Letters
  • Cancer Gene Therapy
  • International Journal of Molecular Sciences

Patrizia Lavia often collaborates with several co-authors, among whom the most frequent include:

  • Michela Damizia
  • Daniela Trisciuoglio
  • Ludovica Altieri
  • Paola Rovella
  • Ilaria Sciamanna

Best Publications

  • E2F target genes and cell-cycle checkpoint control.

    Patrizia Lavia;Pidder Jansen-Dürr

  • A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association.

    Maria De Luca;Patrizia Lavia;Giulia Guarguaglini

  • A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA

    C. Pittoggi;L. Renzi;G. Zaccagnini;D. Cimini

  • p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

    Marilena Ciciarello;Rosamaria Mangiacasale;Martina Casenghi;Maria Zaira Limongi

  • Part of Ran Is Associated with AKAP450 at the Centrosome: Involvement in Microtubule-organizing Activity

    Guy Keryer;Barbara Di Fiore;Claude Celati;Karl Ferdinand Lechtreck

  • Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors

    Giuseppe La Regina;Ruoli Bai;Whilelmina Maria Rensen;Erica Di Cesare

  • The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?

    Italia Anna Asteriti;Wilhelmina Maria Rensen;Catherine Lindon;Patrizia Lavia

  • Exposure of normal and transformed cells to nevirapine, a reverse transcriptase inhibitor, reduces cell growth and promotes differentiation.

    Rosamaria Mangiacasale;Carmine Pittoggi;Ilaria Sciamanna;Angela Careddu

  • p53 Localization at Centrosomes during Mitosis and Postmitotic Checkpoint Are ATM-dependent and Require Serine 15 Phosphorylation

    A. Tritarelli;E. Oricchio;M. Ciciarello;R. Mangiacasale

  • p53-Independent Apoptosis and p53-Dependent Block of DNA Rereplication Following Mitotic Spindle Inhibition in Human Cells

    Martina Casenghi;Rosamaria Mangiacasale;Marcel Tuynder;Perrine Caillet-Fauquet

  • Coincident start sites for divergent transcripts at a randomly selected CpG-rich island of mouse.

    Lavia P;Macleod D;Bird A

  • Spatial control of mitosis by the GTPase Ran

    M. Ciciarello;R. Mangiacasale;P. Lavia

  • Mammalian RanBP1 regulates centrosome cohesion during mitosis

    Barbara Di Fiore;Marilena Ciciarello;Rosamaria Mangiacasale;Antonella Palena

  • Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo.

    G Guarguaglini;L Renzi;F D'Ottavio;B Di Fiore

  • Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time

    Barbara Di Fiore;Marilena Ciciarello;Patrizia Lavia

  • Control of Aurora-A stability through interaction with TPX2

    Maria Giubettini;Italia A. Asteriti;Jacopo Scrofani;Maria De Luca;Maria De Luca

  • Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells

    Liliana Torosantucci;Maria De Luca;Giulia Guarguaglini;Patrizia Lavia

  • Importin β is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells

    Marilena Ciciarello;Rosamaria Mangiacasale;Catherine Thibier;Giulia Guarguaglini

  • New Pyrrole Derivatives with Potent Tubulin Polymerization Inhibiting Activity As Anticancer Agents Including Hedgehog-Dependent Cancer

    Giuseppe La Regina;Ruoli Bai;Antonio Coluccia;Valeria Famiglini

  • Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium.

    Pasquale Buanne;Giuseppina Corrente;Laura Micheli;Antonella Palena

Frequent Co-Authors

Romano Silvestri
Romano Silvestri Sapienza University of Rome
Clara Nervi
Clara Nervi Sapienza University of Rome
Ernest Hamel
Ernest Hamel National Institutes of Health
Angela Santoni
Angela Santoni Sapienza University of Rome
Ettore Novellino
Ettore Novellino University of Naples Federico II
Claudia Martini
Claudia Martini University of Pisa
Silvia Soddu
Silvia Soddu Sapienza University of Rome
Silvia Schenone
Silvia Schenone University of Genoa
Adrian Bird
Adrian Bird University of Edinburgh

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