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Molecular Biology

D-Index
66
Citations
23896
World Ranking
1601
National Ranking
810

Overview

Jennifer L. Martindale is affiliated with the National Institutes of Health in the United States. Their research spans multiple domains within biochemistry, genetics, and molecular biology, with a significant focus on molecular biology as a subfield. They have also contributed to studies in medicine, cancer research, physiology, immunology, and cell biology.

Their work addresses key topics such as RNA research and splicing, RNA modifications related to cancer, telomeres, telomerase, and senescence. Other notable areas of study include cancer-related molecular mechanisms, microRNA in disease regulation, neutrophil, myeloperoxidase and oxidative mechanisms, and circular RNAs in diseases.

Jennifer L. Martindale has published extensively in several scientific venues. Frequent publication platforms include:

  • Nucleic Acids Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Aging
  • Aging Cell

Some of their recent research papers are:

  • "A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells" (2020, eLife)
  • "circSamd4 represses myogenic transcriptional activity of PUR proteins" (2020, Nucleic Acids Research)
  • "AUF1 ligand circPCNX reduces cell proliferation by competing with p21 mRNA to increase p21 production" (2020, Nucleic Acids Research)
  • "Early SRC activation skews cell fate from apoptosis to senescence" (2022, Science Advances)
  • "The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress" (2023, Nature Aging)

Collaborations play a role in their research output, with frequent co-authors including:

  • Myriam Gorospe
  • Rachel Munk
  • Kotb Abdelmohsen
  • Supriyo De
  • Dimitrios Tsitsipatis

Jennifer L. Martindale's contributions are grounded in fundamental studies of cellular and molecular mechanisms underlying RNA biology and cancer. Their research involves exploring how RNA species and protein interactions affect disease regulation, cell proliferation, and senescence processes.

Best Publications

  • Cellular response to oxidative stress: signaling for suicide and survival.

    Jennifer L. Martindale;Nikki J. Holbrook;Nikki J. Holbrook

  • Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

    Karen D. McCullough;Jennifer L. Martindale;Lars-Oliver Klotz;Tak-Yee Aw

  • The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

    Xiantao Wang;Jennifer L. Martindale;Yusen Liu;Nikki J. Holbrook

  • LincRNA-p21 Suppresses Target mRNA Translation

    Je Hyun Yoon;Kotb Abdelmohsen;Subramanya Srikantan;Xiaoling Yang

  • Requirement for ERK Activation in Cisplatin-induced Apoptosis *

    Xiantao Wang;Jennifer L. Martindale;Nikki J. Holbrook

  • Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1.

    Kotb Abdelmohsen;Amaresh C. Panda;Rachel Munk;Ioannis Grammatikakis

  • HuR recruits let-7/RISC to repress c-Myc expression

    Hyeon Ho Kim;Yuki Kuwano;Subramanya Srikantan;Eun Kyung Lee

  • Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response.

    Timothy W. Fawcett;Jennifer L. Martindale;Kathryn Z. Guyton;Tsonwin Hai

  • Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

    Ashish Lal;Krystyna Mazan-Mamczarz;Tomoko Kawai;Xiaoling Yang

  • RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation

    Krystyna Mazan-Mamczarz;Stefanie Galbán;Isabel López de Silanes;Jennifer L. Martindale

  • Functional and morphometric brain dissociation between dyslexia and reading ability.

    Fumiko Hoeft;Ann Meyler;Arvel Hernandez;Connie Juel

  • Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

    Je-Hyun Yoon;Kotb Abdelmohsen;Jiyoung Kim;Xiaoling Yang

  • miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor Expression

    Eun Kyung Lee;Mi Jeong Lee;Kotb Abdelmohsen;Wook Kim

  • P58IPK, a Novel Endoplasmic Reticulum Stress-inducible Protein and Potential Negative Regulator of eIF2α Signaling

    Rika van Huizen;Jennifer L. Martindale;Myriam Gorospe;Nikki J. Holbrook

  • RNA-Binding Proteins HuR and PTB Promote the Translation of Hypoxia-Inducible Factor 1α

    Stefanie Galbán;Yuki Kuwano;Rudolf Pullmann;Jennifer L. Martindale

  • p16INK4a Translation Suppressed by miR-24

    Ashish Lal;Ashish Lal;Hyeon-Ho Kim;Kotb Abdelmohsen;Yuki Kuwano

  • Neural Basis of Dyslexia: A Comparison between Dyslexic and Nondyslexic Children Equated for Reading Ability

    Fumiko Hoeft;Arvel Hernandez;Glenn McMillon;Heather Taylor-Hill

  • Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway.

    Yusen Liu;Jennifer L. Martindale;Myriam Gorospe;Nikki J. Holbrook

  • Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1.

    Isabel López de Silanes;Stefanie Galbán;Jennifer L. Martindale;Xiaoling Yang

  • MKP-1 mRNA Stabilization and Translational Control by RNA-Binding Proteins HuR and NF90

    Yuki Kuwano;Hyeon Ho Kim;Kotb Abdelmohsen;Rudolf Pullmann

Frequent Co-Authors

Myriam Gorospe
Myriam Gorospe National Institutes of Health
Kotb Abdelmohsen
Kotb Abdelmohsen National Institutes of Health
Xiaoling Yang
Xiaoling Yang National Institutes of Health
Ashish Lal
Ashish Lal National Institutes of Health
Nikki J. Holbrook
Nikki J. Holbrook Yale University
Kevin G. Becker
Kevin G. Becker National Institutes of Health
Rafael de Cabo
Rafael de Cabo National Institutes of Health
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Kannanganattu V. Prasanth
Kannanganattu V. Prasanth University of Illinois at Urbana-Champaign
Hideyuki Okano
Hideyuki Okano Keio University

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