Nikki J. Holbrook

Overview

Best Publications

• Oxidants, oxidative stress and the biology of ageing.

  Toren Finkel;Nikki J. Holbrook

  11748
  Citations

• Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions

  Allan Munck;Paul M. Guyre;Nikki J. Holbrook

  4634
  Citations

• Cellular response to oxidative stress: signaling for suicide and survival.

  Jennifer L. Martindale;Nikki J. Holbrook;Nikki J. Holbrook

  3288
  Citations

• Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

  Karen D. McCullough;Jennifer L. Martindale;Lars-Oliver Klotz;Tak-Yee Aw

  2304
  Citations

• Activation of Mitogen-activated Protein Kinase by H2O2: ROLE IN CELL SURVIVAL FOLLOWING OXIDANT INJURY (∗)

  Kathryn Z. Guyton;Yusen Liu;Myriam Gorospe;Qingbo Xu

  1513
  Citations

• The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

  Xiantao Wang;Jennifer L. Martindale;Yusen Liu;Nikki J. Holbrook

  1103
  Citations

• Requirement for ERK Activation in Cisplatin-induced Apoptosis *

  Xiantao Wang;Jennifer L. Martindale;Nikki J. Holbrook

  939
  Citations

• Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

  A J Fornace;D W Nebert;M C Hollander;J D Luethy

  920
  Citations

• HuR regulates p21 mRNA stabilization by UV light.

  W Wang;H Furneaux;H Cheng;M C Caldwell

  647
  Citations

• Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response.

  Timothy W. Fawcett;Jennifer L. Martindale;Kathryn Z. Guyton;Tsonwin Hai

  631
  Citations

• Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I

  Sharon L Cross;Mark B Feinberg;Julie B Wolf;Nikki J Holbrook

  572
  Citations

• Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I

  M Siekevitz;M B Feinberg;N Holbrook;F Wong-Staal

  552
  Citations

• Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

  Xiantao Wang;Karen D. McCullough;Thomas F. Franke;Nikki J. Holbrook

  548
  Citations

• Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

  Thomas Buschmann;Olga Potapova;Anat Bar-Shira;Vladimir N. Ivanov

  431
  Citations

• Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation.

  Yusen Liu;Myriam Gorospe;Chunlin Yang;Nikki J. Holbrook

  416
  Citations

• p21 Waf1/Cip1 protects against p53-mediated apoptosis of human melanoma cells

  Myriam Gorospe;Corrado Cirielli;Xiantao Wang;Prem Seth

  375
  Citations

• P58IPK, a Novel Endoplasmic Reticulum Stress-inducible Protein and Potential Negative Regulator of eIF2α Signaling

  Rika van Huizen;Jennifer L. Martindale;Myriam Gorospe;Nikki J. Holbrook

  355
  Citations

• Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors.

  J E Nagel;R K Chopra;F J Chrest;M T McCoy

  346
  Citations

• Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes

  Yusen Liu;Kathryn Z. Guyton;Myriam Gorospe;Qingbo Xu

  336
  Citations

• Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.

  George Perry;Hanno Roder;Akihiko Nunomura;Akihiko Nunomura;Atsushi Takeda

  329
  Citations