2017 - Fellow of the American Association for the Advancement of Science (AAAS)
His main research concerns Biochemistry, Molecular biology, Biophysics, Viral protein and DNA. He is interested in Cytidine deaminase, which is a field of Biochemistry. His studies in Molecular biology integrate themes in fields like Congenic, Binding domain, Glycosylation, Conserved sequence and Capsid.
Viral replication is closely connected to Helicase in his research, which is encompassed under the umbrella topic of Biophysics. Viral protein is a primary field of his research addressed under Virology. His DNA research focuses on subjects like Random hexamer, which are linked to Minichromosome maintenance.
Xiaojiang S. Chen mainly investigates DNA, Helicase, Biochemistry, Molecular biology and Biophysics. His DNA research includes themes of RNA, Protein subunit, Nucleic acid and Mutation. Xiaojiang S. Chen interconnects Crystallography, Random hexamer, ATP hydrolysis, Minichromosome maintenance and DNA replication in the investigation of issues within Helicase.
His work is dedicated to discovering how Random hexamer, Nucleic acid thermodynamics are connected with Conformational change and other disciplines. His biological study spans a wide range of topics, including Mutant, Capsid, Antibody, Viral protein and Binding site. His study in Biophysics is interdisciplinary in nature, drawing from both Pentamer, Plasma protein binding, Chromosomal translocation, Viral replication and Protein structure.
His primary scientific interests are in DNA, Helicase, Biochemistry, Biophysics and Cell biology. His DNA study incorporates themes from APOBEC, Nucleic acid and Stereochemistry. His work in APOBEC tackles topics such as Deamination which are related to areas like Molecular biology and Genetics.
Xiaojiang S. Chen has included themes like ATP hydrolysis, Base pair, DNA replication and Minichromosome maintenance in his Helicase study. His Biophysics research is multidisciplinary, incorporating elements of Pentamer, In vitro and Peptide. His Cell biology research incorporates themes from RNA and Receptor.
Xiaojiang S. Chen mostly deals with DNA, Nucleic acid, Cytosine, Biochemistry and Cytidine deaminase. His work deals with themes such as Plasma protein binding, APOBEC3G, Hydrolase, Biophysics and RNase P, which intersect with Nucleic acid. While the research belongs to areas of Cytosine, Xiaojiang S. Chen spends his time largely on the problem of Deamination, intersecting his research to questions surrounding Molecular biology, APOBEC and Genetics.
His Molecular biology study often links to related topics such as RNA. In the subject of general Biochemistry, his work in Protein domain, Helicase and MCM10 is often linked to Context, thereby combining diverse domains of study. Xiaojiang S. Chen studied Cytidine deaminase and Binding site that intersect with Heterogeneous ribonucleoprotein particle and Bioinformatics.
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Structure of Small Virus-Like Particles Assembled from the L1 Protein of Human Papillomavirus 16
Xiaojiang S. Chen;Robert L. Garcea;Ilya Goldberg;Gregory Casini.
Molecular Cell (2000)
The structure and function of MCM from archaeal M.Thermoautotrophicum
Ryan J. Fletcher;Brooke E. Bishop;Ronald P. Leon;Robert A. Sclafani.
Nature Structural & Molecular Biology (2003)
Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen
Dahai Gai;Rui Zhao;Dawei Li;Carla V. Finkielstein.
Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Dawei Li;Rui Zhao;Wayne Lilyestrom;Dahai Gai.
The APOBEC-2 crystal structure and functional implications for the deaminase AID
Courtney Prochnow;Ronda Bransteitter;Michael G. Klein;Myron F. Goodman.
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications
Lauren G. Holden;Courtney Prochnow;Y. Paul Chang;Ronda Bransteitter.
Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry
Xiaojiang S. Chen;Thilo Stehle;Stephen C. Harrison.
The EMBO Journal (1998)
Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1.
Xiaojiang S Chen;Gregory Casini;Stephen C Harrison;Robert L Garcea.
Journal of Molecular Biology (2001)
Interactions between Papillomavirus L1 and L2 Capsid Proteins
Renée L. Finnen;Kimberly D. Erickson;Xiaojiang S. Chen;Robert L. Garcea.
Journal of Virology (2003)
Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein
Susan A Boackle;V.Michael Holers;Xiaojiang Chen;Gerda Szakonyi.
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