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Immunology

D-Index
67
Citations
15049
World Ranking
2679
National Ranking
1282

Overview

Joel M. Guthridge is affiliated with the Oklahoma Medical Research Foundation in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focused emphasis on Rheumatology, Immunology, Molecular Biology, Nephrology, and Physiology.

The main topics of their work include Systemic Lupus Erythematosus Research, Atherosclerosis and Cardiovascular Diseases, T-cell and B-cell Immunology, Renal Diseases and Glomerulopathies, Salivary Gland Disorders and Functions, Monoclonal and Polyclonal Antibodies Research, and Cytokine Signaling Pathways and Interactions.

Joel M. Guthridge has coauthored numerous publications with researchers such as Judith A. James, Jennifer H. Anolik, Jill P. Buyon, Peter Izmirly, and Susan Macwana.

The scientist's recent papers include these publications:

  • Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study, 2020, EClinicalMedicine
  • The promise of precision medicine in rheumatology, 2022, Nature Medicine
  • Notch signalling drives synovial fibroblast identity and arthritis pathology, 2020, Nature
  • Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells, 2022, Nature Communications
  • Granzyme K activates the entire complement cascade, 2025, Nature

The predominant venues where Joel M. Guthridge frequently publishes are Annals of the Rheumatic Diseases, bioRxiv (Cold Spring Harbor Laboratory), Arthritis & Rheumatology, The Journal of Rheumatology, and Nature Communications.

Best Publications

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • Complement C3 activation is required for antiphospholipid antibody-induced fetal loss.

    V. Michael Holers;Guillermina Girardi;Lian Mo;Joel M. Guthridge

  • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

    Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice

  • Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

    Anne Hinks;Anne Hinks;Joanna E. Cobb;Joanna E. Cobb;Miranda C. Marion;Sampath Prahalad

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

    Evan Der;Hemant Suryawanshi;Pavel Morozov;Manjunath Kustagi

  • A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.

    Swapan K. Nath;Shizhong Han;Xana Kim-Howard;Jennifer A. Kelly

  • Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

    Nan Shen;Qiong Fu;Qiong Fu;Yun Deng;Yun Deng;Xiaoxia Qian

  • Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus

    Lauren L Ritterhouse;Sherry R Crowe;Timothy B Niewold;Diane L Kamen

  • Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

    Indra Adrianto;Feng Wen;Amanda Templeton;Graham B. Wiley

  • PD-1hiCXCR5– T peripheral helper cells promote B cell responses in lupus via MAF and IL-21

    Alexandra V. Bocharnikov;Joshua Keegan;Vanessa S. Wacleche;Ye Cao

  • Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification.

    Melissa E Munroe;Rufei Lu;Yan D Zhao;Dustin A Fife

  • Identification of unique microRNA signature associated with lupus nephritis.

    Jeannie L. Te;Igor M. Dozmorov;Joel M. Guthridge;Kim L. Nguyen

  • Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

    Jian Zhao;Hui Wu;Melanie Khosravi;Huijuan Cui

  • Mice Deficient in Complement Receptors 1 and 2 Lack a Tissue Injury-Inducing Subset of the Natural Antibody Repertoire

    Sherry D. Fleming;Terez Shea-Donohue;Terez Shea-Donohue;Joel M. Guthridge;Liudmila Kulik

  • Structure of complement receptor 2 in complex with its C3d ligand.

    Gerda Szakonyi;Joel M. Guthridge;Dawei Li;Kendra Young

  • Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study

    Christopher J. Lessard;Christopher J. Lessard;Christopher J. Lessard;Indra Adrianto;John A. Ice;Graham B. Wiley

  • Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis

    Güher Saruhan-Direskeneli;Travis Hughes;Kenan Aksu;Gokhan Keser

  • X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

    Ke Liu;Biji T. Kurien;Sarah L. Zimmerman;Kenneth M. Kaufman

  • Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies.

    Rufei Lu;Rufei Lu;Melissa E. Munroe;Joel M. Guthridge;Krista M. Bean

  • Evaluation of Imputation-based Association in and around the Integrin-α-M (ITGAM) gene and Replication of Robust Association between a Non-synonymous Functional variant within ITGAM and Systemic lupus erythematosus (SLE)

    Shizhong Han;Xana Kim-Howard;Harshal Deshmukh;Yoichiro Kamatani

Frequent Co-Authors

Judith A. James
Judith A. James Oklahoma Medical Research Foundation
John B. Harley
John B. Harley United States Department of Veterans Affairs
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Joan T. Merrill
Joan T. Merrill Oklahoma Medical Research Foundation
Gary S. Gilkeson
Gary S. Gilkeson Medical University of South Carolina
Timothy J. Vyse
Timothy J. Vyse King's College London

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