What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Biochemistry, Molecular biology, Hemoglobin, Peptide and Cell. Vernon M. Ingram integrates Biochemistry with Ribose in his research. His Molecular biology research is multidisciplinary, incorporating elements of DNA methyltransferase, Histone, DNA, HeLa and In vitro recombination.
His work on Globin as part of general Hemoglobin research is frequently linked to Haemoglobin C disease, thereby connecting diverse disciplines of science. His Peptide research is multidisciplinary, relying on both Amino acid, Peptide sequence, Hemoglobin A and Thioflavin. His work on Anemia sickle-cell as part of general Cell study is frequently linked to Chemical difference, Population and Sephadex, therefore connecting diverse disciplines of science.
His most cited work include:
- Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells: The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases☆ (763 citations)
- Gene Mutations in Human Hæmoglobin: the Chemical Difference Between Normal and Sickle Cell Hæmoglobin (681 citations)
- n -Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells (646 citations)
What are the main themes of his work throughout his whole career to date?
Vernon M. Ingram mostly deals with Biochemistry, Molecular biology, Hemoglobin, Cell biology and Peptide. His studies in Amino acid, Lysine, Alanine, RNA and Yeast are all subfields of Biochemistry research. In general Amino acid study, his work on Valine often relates to the realm of Acceptor, thereby connecting several areas of interest.
His Molecular biology study combines topics from a wide range of disciplines, such as Histone, DNA, Complementary DNA, Globin and Embryo. His Hemoglobin research incorporates elements of Endocrinology, Erythropoiesis and Gene mutation. His work investigates the relationship between Peptide and topics such as Glutamic acid that intersect with problems in Residue.
He most often published in these fields:
- Biochemistry (46.25%)
- Molecular biology (28.12%)
- Hemoglobin (18.75%)
What were the highlights of his more recent work (between 1996-2009)?
- Biochemistry (46.25%)
- Biophysics (8.75%)
- Peptide (16.88%)
In recent papers he was focusing on the following fields of study:
Vernon M. Ingram focuses on Biochemistry, Biophysics, Peptide, Cell biology and Neurotoxicity. Vernon M. Ingram combines subjects such as Combinatorial chemistry and Amyloid with his study of Biochemistry. His Fibril study in the realm of Biophysics interacts with subjects such as Blocking.
Vernon M. Ingram focuses mostly in the field of Peptide, narrowing it down to topics relating to Peptide sequence and, in certain cases, Voltage-dependent calcium channel. His work in Cell biology addresses subjects such as Calcium, which are connected to disciplines such as Neuron. In his research, Plasma protein binding is intimately related to Molecular biology, which falls under the overarching field of Green fluorescent protein.
Between 1996 and 2009, his most popular works were:
- Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. (188 citations)
- Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule (133 citations)
- Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases (120 citations)
In his most recent research, the most cited papers focused on:
Vernon M. Ingram spends much of his time researching Biochemistry, Intracellular, Cell biology, Huntingtin and Calcium. His research investigates the connection between Biochemistry and topics such as Amyloid that intersect with issues in Small molecule and Biophysics. His Cell biology research incorporates themes from Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 4.
His research integrates issues of Intrabody, Neurodegeneration, Single-domain antibody and Binding site in his study of Huntingtin. His Calcium study combines topics in areas such as Calcium-Calmodulin-Dependent Protein Kinases, Kinase, Mitochondrion and Phosphorylation. His work in Peptide tackles topics such as Peptide sequence which are related to areas like Voltage-dependent calcium channel.
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