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Chemistry

D-Index
44
Citations
6597
World Ranking
16921
National Ranking
4179

Overview

James M. Manning is affiliated with Northeastern University in the United States. Their research primarily intersects the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, Manning's focus encompasses Pediatrics, Perinatology and Child Health, Cell Biology, Genetics, and Molecular Biology.

The scientist's work addresses several main topics, including:

  • Neonatal Health and Biochemistry
  • Hemoglobin structure and function
  • Hemoglobinopathies and Related Disorders
  • Heme Oxygenase-1 and Carbon Monoxide

Manning has contributed to the academic literature with notable papers such as:

  • "Embryonic and Fetal Human Hemoglobins: Structures, Oxygen Binding, and Physiological Roles," published in 2020 in Sub-cellular biochemistry/Subcellular biochemistry
  • "Nano gel filtration reveals how fish hemoglobins release oxygen: The Root Effect," published in 2020 in Analytical Biochemistry (authored by Lois R. Manning)

Frequent co-authors include:

  • Lois R. Manning
  • Antoine Dumoulin
  • Júlio C. Padovan
  • Brian T. Chait

The scientist has published in venues such as:

  • Sub-cellular biochemistry/Subcellular biochemistry
  • Analytical Biochemistry

This body of work reflects a multidisciplinary approach linking molecular and physiological studies related to hemoglobin and neonatal biochemistry.

Best Publications

  • Determination of d- and l-Amino Acids by Ion Exchange Chromatography as l-d and l-l Dipeptides

    James M. Manning;Stanford Moore

  • Potassium cyanate as an inhibitor of the sickling of erythrocytes in vitro.

    Anthony Cerami;James M. Manning

  • Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus.

    Carol A. Rouzer;William A. Scott;Zanvil A. Cohn;Peter Blackburn

  • Identification of L-methionine S-sulfoximine as the diastereoisomer of L-methionine SR-sulfoximine that inhibits glutamine synthetase.

    James M. Manning;Stanford Moore;William Bruce Rowe;Alton Meister

  • Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity.

    Shigetoshi Sugio;Gregory A. Petsko;James M. Manning;Kenji Soda

  • Amyloid-forming Peptides from β2-Microglobulin—Insights into the Mechanism of Fibril Formation in Vitro

    Susan Jones;James Manning;Neil M. Kad;Sheena E. Radford

  • Determination of D- and L-amino acid residues in peptides. Use of tritiated hydrochloric acid to correct for racemization during acid hydrolysis

    James M. Manning

  • Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase.

    D Peisach;D.M Chipman;P.W Van Ophem;J.M Manning

  • Fatty Acid Composition of Low-Density Lipoprotein Influences Its Susceptibility to Autoxidation

    Michael J. Thomas;Todd Thornburg;James Manning;Kelly Hooper

  • The Effects of Cyanate In Vitro on Red Blood Cell Metabolism and Function in Sickle Cell Anemia

    Frank G. De Furia;Denis R. Miller;Anthony Cerami;James M. Manning

  • Studies on the mechanism of action of cyanate in sickle cell disease. Oxygen affinity and gelling properties of hemoglobin S carbamylated on specific chains.

    Alan M. Nigen;Njifutié Njikam;Choong K. Lee;James M. Manning

  • Subunit dissociations in natural and recombinant hemoglobins.

    L R Manning;W T Jenkins;J R Hess;K Vandegriff

  • Increased Survival of Sickle-Cell Erythrocytes after Treatment In Vitro with Sodium Cyanate

    Peter N. Gillette;James M. Manning;Anthony Cerami

  • Oxygen-linked binding sites for inorganic anions to hemoglobin.

    A M Nigen;J M Manning;J O Alben

  • Schiff base adducts of glyceraldehyde with hemoglobin. Differences in the Amadori rearrangement at the alpha-amino groups.

    A S Acharya;L G Sussman;J M Manning

  • Labeling of hemoglobin with pyridoxal phosphate.

    R Benesch;R E Benesch;S Kwong;A S Acharya

  • Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme.

    A Scaloni;W.M. Jones;D Barra;M Pospischil

  • Reaction of glycolaldehyde with proteins: latent crosslinking potential of alpha-hydroxyaldehydes.

    Unknown

  • Kinetics of the Carbamylation of the Amino Groups of Sickle Cell Hemoglobin by Cyanate

    Choong K. Lee;James M. Manning

  • PHARMACOLOGY OF CYANATE. I. GENERAL EFFECTS ON EXPERIMENTAL ANIMALS

    A. Cerami;T. A. Allen;J. H. Graziano;F. G. deFURIA

  • Interaction of gamma-glutamyl transpeptidase with acivicin.

    E Stole;T K Smith;J M Manning;A Meister

Frequent Co-Authors

Brian T. Chait
Brian T. Chait Rockefeller University
Dagmar Ringe
Dagmar Ringe Brandeis University
Anthony Cerami
Anthony Cerami Araim Pharmaceuticals (United States)
Gregory A. Petsko
Gregory A. Petsko Cornell University
Kenji Soda
Kenji Soda Kansai University
Andrea Scaloni
Andrea Scaloni National Academies of Sciences, Engineering, and Medicine
Olaf Schneewind
Olaf Schneewind University of Chicago
Shiroh Futaki
Shiroh Futaki Kyoto University
Donatella Barra
Donatella Barra Sapienza University of Rome
Emil C. Gotschlich
Emil C. Gotschlich Rockefeller University

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