Paul A. Marks

Research.com Recognitions

• 1991 - US President's National Medal of Science "For his contribution to hematology in defining the genetic basis for G6PD deficiency and thalassemia, and discovery of an approach to control cancer cell proliferation with new inducers of differentiation.", Presented by President Bush at a White House Rose Garden Ceremony on September 16, 1991.
• 1982 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1973 - Member of the National Academy of Sciences

Overview

Best Publications

• Histone deacetylases and cancer: causes and therapies.

  Paul A. Marks;Richard A. Rifkind;Victoria M. Richon;Ronald Breslow

  2878
  Citations

• Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors.

  Michael S. Finnin;Jill R. Donigian;Alona Cohen;Victoria M. Richon

  2525
  Citations

• A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

  Victoria M. Richon;Stephane Emiliani;Eric Verdin;Yael Webb

  1193
  Citations

• Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

  E. Hockly;V.M. Richon;B. Woodman;D.L. Smith

  1051
  Citations

• Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications

  Constantine S. Mitsiades;Nicholas S. Mitsiades;Ciaran J. McMullan;Vassiliki Poulaki

  670
  Citations

• The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin

  Lisa M. Butler;Xianbo Zhou;Wei-Sheng Xu;Howard I. Scher

  664
  Citations

• Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

  Melissa J. Peart;Gordon K. Smyth;Ryan K. van Laar;David D. Bowtell

  661
  Citations

• Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

  V M Richon;Y Webb;R Merger;T Sheppard

  651
  Citations

• A new group of potent inducers of differentiation in murine erythroleukemia cells.

  Roberta C. Reuben;Richard L. Wife;Ronald Breslow;Richard A. Rifkind

  491
  Citations

• The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells.

  Pamela N. Munster;Tiffany Troso-Sandoval;Neal Rosen;Richard Rifkind

  481
  Citations

• Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia.

  Li-Zhen He;Thomas Tolentino;Peter Grayson;Sue Zhong

  379
  Citations

• Molecular sequelae of histone deacetylase inhibition in human malignant B cells

  Nicholas Mitsiades;Constantine S. Mitsiades;Paul G. Richardson;Ciaran McMullan

  373
  Citations

• Cloning and characterization of a histone deacetylase, HDAC9

  Xianbo Zhou;Paul A. Marks;Richard A. Rifkind;Victoria M. Richon

  372
  Citations

• Lipid synthesis in human leukocytes, platelets, and erythrocytes.

  Paul A. Marks;Alfred Gellhorn;Chev Kidson

  355
  Citations

• Novel potent inducers of terminal differentiation and methods of use thereof

  Ronald Breslow;Paul A. Marks;Richard A. Rifkind;Branko Jursic

  307
  Citations

• Tumor promoters inhibit spontaneous and induced differentiation of murine erythroleukemia cells in culture

  H Yamasaki;E Fibach;U Nudel;I B Weinstein

  306
  Citations

• Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.

  Masao Tanaka;Joseph Levy;Masaaki Terada;Ronald Breslow

  305
  Citations

• INHIBITION OF MAMMALIAN GLUCOSE-6-PHOSPHATE DEHYDROGENASE BY STEROIDS.

  Paul A. Marks;Julia Banks

  302
  Citations

• Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents

  Mandana Namdar;Gisela Perez;Lang Ngo;Paul A. Marks

  260
  Citations

• Effect of Hexamethylene Bisacetamide on the Commitment to Differentiation of Murine Erythroleukemia Cells

  Eitan Fibach;Roberta C. Reuben;Richard A. Rifkind;Paul A. Marks

  257
  Citations