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D-Index & Metrics

Chemistry

D-Index
114
Citations
53851
World Ranking
655
National Ranking
274

Research.com Recognitions

  • 2010 - Perkin Medal, Society of Chemical Industry, American Section
  • 2009 - Fellow of the American Chemical Society
  • 2006 - Member of the European Academy of Sciences
  • 2003 - Welch Award in Chemistry, Robert A. Welch Foundation
  • 1999 - Priestley Medal, American Chemical Society (ACS)
  • 1991 - US President's National Medal of Science "For his incisive work on enzyme mimics that has built bridges between chemistry and biochemistry, and for his seminal work on novel conjugated molecules and a new class of anticancer agents.", Presented by President Bush at a White House Rose Garden Ceremony on September 16, 1991.
  • 1989 - NAS Award in Chemical Sciences, National Academy of Sciences (US) For his imaginative invention of novel synthetic methods, his enunciation of the mechanism of enzyme reactions, and his development of systems that mimic enzyme activity.
  • 1989 - William H. Nichols Medal, American Chemical Society (ACS)
  • 1987 - Arthur C. Cope Award, American Chemical Society (ACS)
  • 1986 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1971 - Centenary Prize, Royal Society of Chemistry (UK)
  • 1966 - ACS Award in Pure Chemistry, American Chemical Society (ACS)
  • 1966 - Member of the National Academy of Sciences
  • 1959 - Fellow of Alfred P. Sloan Foundation

Overview

Ronald Breslow was affiliated with Columbia University in the United States. Their career included contributions to chemistry, particularly in the development of enzyme mimics and the study of novel conjugated molecules, as well as research into a new class of anticancer agents.

Breslow's work received recognition from multiple scientific organizations and was acknowledged through various awards and honors throughout their career.

  • Perkin Medal, Society of Chemical Industry, American Section (2010)
  • Fellow of the American Chemical Society (2009)
  • Member of the European Academy of Sciences (2006)
  • Welch Award in Chemistry, Robert A. Welch Foundation (2003)
  • Priestley Medal, American Chemical Society (ACS) (1999)
  • US President's National Medal of Science (1991), awarded "For his incisive work on enzyme mimics that has built bridges between chemistry and biochemistry, and for his seminal work on novel conjugated molecules and a new class of anticancer agents," presented by President Bush at a White House Rose Garden Ceremony on September 16, 1991
  • William H. Nichols Medal, American Chemical Society (ACS) (1989)
  • NAS Award in Chemical Sciences, National Academy of Sciences (US) (1989), awarded for "imaginative invention of novel synthetic methods, enunciation of the mechanism of enzyme reactions, and development of systems that mimic enzyme activity"
  • Arthur C. Cope Award, American Chemical Society (ACS) (1987)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1986)
  • Centenary Prize, Royal Society of Chemistry (UK) (1971)
  • Member of the National Academy of Sciences (1966)
  • ACS Award in Pure Chemistry, American Chemical Society (ACS) (1966)
  • Fellow of Alfred P. Sloan Foundation (1959)

Throughout their career, Breslow's research bridged disciplines within chemistry and biochemistry by focusing on enzyme reaction mechanisms and synthetic methods designed to replicate enzymatic functions.

Their work on enzyme mimics notably formed a critical link between chemical synthesis and biological function, contributing to the understanding of how enzymes operate at a molecular level. This included the invention of new synthetic methods aimed at mimicking enzyme activity.

Additionally, Breslow contributed to the study of novel conjugated molecules, which have applications across several chemical disciplines, and the exploration of a new class of anticancer agents, marking involvement in medicinal chemistry.

Ronald Breslow was recognized as a member of prestigious scientific societies, including the National Academy of Sciences and the European Academy of Sciences, reflecting engagement with leading scientific communities.

Best Publications

  • Histone deacetylases and cancer: causes and therapies.

    Paul A. Marks;Richard A. Rifkind;Victoria M. Richon;Ronald Breslow

  • Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors.

    Michael S. Finnin;Jill R. Donigian;Alona Cohen;Victoria M. Richon

  • On the Mechanism of Thiamine Action. IV.1 Evidence from Studies on Model Systems

    Ronald Breslow

  • Hydrophobic acceleration of Diels-Alder reactions

    Darryl C. Rideout;Ronald Breslow

  • Biomimetic Reactions Catalyzed by Cyclodextrins and Their Derivatives.

    Ronald Breslow;Steven D. Dong

  • Hydrophobic effects on simple organic reactions in water

    Ronald Breslow

  • Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug.

    Paul A Marks;Ronald Breslow

  • Biomimetic Chemistry and Artificial Enzymes: Catalysis by Design

    Ronald Breslow

  • A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

    Victoria M. Richon;Stephane Emiliani;Eric Verdin;Yael Webb

  • Histone deacetylase inhibitors as new cancer drugs.

    Paul A. Marks;Victoria M. Richon;Ronald Breslow;Richard A. Rifkind

  • Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

    V M Richon;Y Webb;R Merger;T Sheppard

  • Covalently Bridging Gaps in Single-Walled Carbon Nanotubes with Conducting Molecules

    Xuefeng Guo;Joshua P. Small;Jennifer E. Klare;Yiliang Wang

  • Biomimetic control of chemical selectivity

    Ronald Breslow

  • Selective diels-alder reactions in aqueous solutions and suspensions

    Ronald Breslow;Uday Maitra;Darryl Rideout

  • On the mechanism of the formose reaction

    Ronald Breslow

  • A new group of potent inducers of differentiation in murine erythroleukemia cells.

    Roberta C. Reuben;Richard L. Wife;Ronald Breslow;Richard A. Rifkind

  • An "artificial enzyme" combining a metal catalytic group and a hydrophobic binding cavity.

    Ronald Breslow;Larry E. Overman

  • Intramolecular nitrene carbon-hydrogen insertions mediated by transition-metal complexes as nitrogen analogs of cytochrome P-450 reactions

    Ronald Breslow;Samuel H. Gellman

  • Probing the conductance superposition law in single-molecule circuits with parallel paths

    H. Vazquez;R. Skouta;S. Schneebeli;M. Kamenetska;M. Kamenetska

  • RAPID DEUTERIUM EXCHANGE IN THIAZOLIUM SALTS1

    Ronald Breslow

Frequent Co-Authors

Richard A. Rifkind
Richard A. Rifkind Memorial Sloan Kettering Cancer Center
Paul A. Marks
Paul A. Marks Columbia University
Latha Venkataraman
Latha Venkataraman Columbia University
Mark S. Hybertsen
Mark S. Hybertsen Brookhaven National Laboratory
Anthony W. Czarnik
Anthony W. Czarnik Illumina (United States)
Barry B. Snider
Barry B. Snider Brandeis University
Steven C. Zimmerman
Steven C. Zimmerman University of Illinois at Urbana-Champaign
Jeffrey D. Winkler
Jeffrey D. Winkler University of Pennsylvania
Uday Maitra
Uday Maitra Indian Institute of Science

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