Stereochemistry, Autophagy, Organic chemistry, Lysosome and Cancer research are his primary areas of study. His Stereochemistry research incorporates elements of Enantioselective synthesis and Stereoselectivity. His Autophagy study incorporates themes from Cancer, PI3K/AKT/mTOR pathway and Programmed cell death.
The Organic chemistry study combines topics in areas such as Combinatorial chemistry and Antithrombin. His work focuses on many connections between Lysosome and other disciplines, such as Chloroquine, that overlap with his field of interest in Pharmacology, ATG16L1 and Cancer cell. His Cancer research research is multidisciplinary, incorporating elements of Cell cycle, Cell cycle checkpoint and Cell growth.
His primary scientific interests are in Stereochemistry, Intramolecular force, Stereoselectivity, Organic chemistry and Ring. As a member of one scientific family, he mostly works in the field of Stereochemistry, focusing on Cycloaddition and, on occasion, Mannich reaction. His Intramolecular force research is multidisciplinary, incorporating perspectives in Photochemistry, Lactone and Diterpene.
In his papers, Jeffrey D. Winkler integrates diverse fields, such as Stereoselectivity and Tandem. Organic chemistry is often connected to Combinatorial chemistry in his work. Jeffrey D. Winkler has researched Intramolecular reaction in several fields, including Ketone and Enone.
His scientific interests lie mostly in Autophagy, Cell biology, Cancer research, Cancer and Pharmacology. His biological study spans a wide range of topics, including Cell, Haematopoiesis, Cell growth, Cancer cell and Programmed cell death. His Cancer research research incorporates themes from Acetylation, ACSS2, Oxidative stress and Histone.
The various areas that Jeffrey D. Winkler examines in his Cancer study include Lysosome, BNIP3 Gene, Biochemistry, Radioresistance and Clonogenic assay. Jeffrey D. Winkler has included themes like mTORC1 and Molecular biology in his Lysosome study. His studies in Pharmacology integrate themes in fields like Endocrinology, Estrogen and Estrogen receptor, GPER.
His main research concerns Autophagy, Cancer research, Cell biology, Cell growth and Cancer. His Autophagy research includes themes of Haematopoiesis, Senescence, Leukemia, PI3K/AKT/mTOR pathway and Programmed cell death. His work deals with themes such as Viability assay, Hypoxia and Pharmacology, which intersect with Programmed cell death.
His study in the field of Hepatocellular carcinoma is also linked to topics like Embolization. His Cell growth research incorporates elements of Inflammation, T cell, Dendritic cell, Immediate early protein and ATG16L1. In his study, which falls under the umbrella issue of Cancer, Chloroquine, Cytotoxicity, Cancer cell and Mechanism of action is strongly linked to Lysosome.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Tandem Diels−Alder Cycloadditions in Organic Synthesis
Jeffrey D. Winkler.
Chemical Reviews (1996)
Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
Xiao Hong Ma;Sheng Fu Piao;Souvik Dey;Quentin McAfee.
Journal of Clinical Investigation (2014)
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Quentin McAfee;Zhihui Zhang;Arabinda Samanta;Samuel M. Levi.
Proceedings of the National Academy of Sciences of the United States of America (2012)
De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers
Sungwook Choi;Andre Isaacs;Dylan Clements;Dahui Liu.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Reduction of Clofazimine by Mycobacterial Type 2 NADH:Quinone Oxidoreductase A PATHWAY FOR THE GENERATION OF BACTERICIDAL LEVELS OF REACTIVE OXYGEN SPECIES
Takahiro Yano;Sacha Kassovska-Bratinova;J. Shin Teh;Jeffrey Winkler.
Journal of Biological Chemistry (2011)
Nontoxic Membrane-Active Antimicrobial Arylamide Oligomers†
Dahui Liu;Sungwook Choi;Bin Chen;Bin Chen;Robert J. Doerksen.
Angewandte Chemie (2004)
Photodynamic Fluorescent Metal Ion Sensors with Parts per Billion Sensitivity
Jeffrey D. Winkler;and Corinne M. Bowen;Veronique Michelet.
Journal of the American Chemical Society (1998)
2 + 2 PHOTOCYCLOADDITION/FRAGMENTATION STRATEGIES FOR THE SYNTHESIS OF NATURAL AND UNNATURAL PRODUCTS
Jeffrey D. Winkler;Corinne Mazur. Bowen;Fina. Liotta.
Chemical Reviews (1995)
Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension.
Fumito Ichinose;Juan Erana-Garcia;Jonathan Hromi;Yehuda Raveh.
Critical Care Medicine (2001)
The first total synthesis of ingenol
Jeffrey D. Winkler;Meagan B. Rouse;Michael F. Greaney;Sean J. Harrison.
Journal of the American Chemical Society (2002)
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