What is he best known for?
The fields of study he is best known for:
- Organic chemistry
- Enzyme
- Gene
Stereochemistry, Autophagy, Organic chemistry, Lysosome and Cancer research are his primary areas of study.
His Stereochemistry research incorporates elements of Enantioselective synthesis and Stereoselectivity.
His Autophagy study incorporates themes from Cancer, PI3K/AKT/mTOR pathway and Programmed cell death.
The Organic chemistry study combines topics in areas such as Combinatorial chemistry and Antithrombin.
His work focuses on many connections between Lysosome and other disciplines, such as Chloroquine, that overlap with his field of interest in Pharmacology, ATG16L1 and Cancer cell.
His Cancer research research is multidisciplinary, incorporating elements of Cell cycle, Cell cycle checkpoint and Cell growth.
His most cited work include:
- Tandem Diels−Alder Cycloadditions in Organic Synthesis (261 citations)
- Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma (254 citations)
- Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency (252 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Stereochemistry, Intramolecular force, Stereoselectivity, Organic chemistry and Ring.
As a member of one scientific family, he mostly works in the field of Stereochemistry, focusing on Cycloaddition and, on occasion, Mannich reaction.
His Intramolecular force research is multidisciplinary, incorporating perspectives in Photochemistry, Lactone and Diterpene.
In his papers, Jeffrey D. Winkler integrates diverse fields, such as Stereoselectivity and Tandem.
Organic chemistry is often connected to Combinatorial chemistry in his work.
Jeffrey D. Winkler has researched Intramolecular reaction in several fields, including Ketone and Enone.
He most often published in these fields:
- Stereochemistry (47.39%)
- Intramolecular force (24.17%)
- Stereoselectivity (21.33%)
What were the highlights of his more recent work (between 2012-2021)?
- Autophagy (8.53%)
- Cell biology (6.64%)
- Cancer research (5.69%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Autophagy, Cell biology, Cancer research, Cancer and Pharmacology.
His biological study spans a wide range of topics, including Cell, Haematopoiesis, Cell growth, Cancer cell and Programmed cell death.
His Cancer research research incorporates themes from Acetylation, ACSS2, Oxidative stress and Histone.
The various areas that Jeffrey D. Winkler examines in his Cancer study include Lysosome, BNIP3 Gene, Biochemistry, Radioresistance and Clonogenic assay.
Jeffrey D. Winkler has included themes like mTORC1 and Molecular biology in his Lysosome study.
His studies in Pharmacology integrate themes in fields like Endocrinology, Estrogen and Estrogen receptor, GPER.
Between 2012 and 2021, his most popular works were:
- Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma (254 citations)
- CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers. (118 citations)
- A unified approach to targeting the lysosome’s degradative and growth signaling roles (80 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Enzyme
- Gene
His main research concerns Autophagy, Cancer research, Cell biology, Cell growth and Cancer.
His Autophagy research includes themes of Haematopoiesis, Senescence, Leukemia, PI3K/AKT/mTOR pathway and Programmed cell death.
His work deals with themes such as Viability assay, Hypoxia and Pharmacology, which intersect with Programmed cell death.
His study in the field of Hepatocellular carcinoma is also linked to topics like Embolization.
His Cell growth research incorporates elements of Inflammation, T cell, Dendritic cell, Immediate early protein and ATG16L1.
In his study, which falls under the umbrella issue of Cancer, Chloroquine, Cytotoxicity, Cancer cell and Mechanism of action is strongly linked to Lysosome.
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