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Medicine

D-Index
84
Citations
48419
World Ranking
14819
National Ranking
7490

Overview

Ravi K. Amaravadi is affiliated with the University of Pennsylvania in the United States. Their research spans Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Oncology, Immunology, Molecular Biology, Epidemiology, and Infectious Diseases.

Their work concentrates on several interconnected topics within cancer and immunology research. These include Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Immunotherapy and Immune Responses, Autophagy in Disease and Therapy, Cutaneous Melanoma Detection and Management, Melanoma and MAPK Pathways, and Immune Cell Function and Interaction.

Amaravadi has published extensively in several scientific venues. Frequent publication venues for their work include:

  • Journal of Clinical Oncology
  • Nature Communications
  • Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research

The collaboration network of Amaravadi features frequent coauthors who have worked with them on multiple studies. Among these collaborators are Tara C. Mitchell, Lynn M. Schuchter, Giorgos C. Karakousis, Xiaowei Xu, and Alexander C. Huang.

Several notable papers reflect Amaravadi's engagement with autophagy, immunology, and cancer therapies. These recent publications include:

  • "Autophagy in major human diseases" (2021), published in The EMBO Journal
  • "Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms" (2020), published in Immunity
  • "SIRT1 is downregulated by autophagy in senescence and ageing" (2020), published in Nature Cell Biology
  • "Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials" (2021), published in Nature Communications
  • "A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients" (2020), published in Clinical Cancer Research

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

    Jeffrey A. Sosman;Kevin B. Kim;Lynn Schuchter;Rene Gonzalez

  • Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

    Christina Twyman-Saint Victor;Andrew J. Rech;Amit Maity;Ramesh Rengan;Ramesh Rengan

  • T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

    Alexander C. Huang;Michael A. Postow;Michael A. Postow;Robert J. Orlowski;Rosemarie Mick

  • TOX transcriptionally and epigenetically programs CD8 + T cell exhaustion

    Omar Khan;Josephine R. Giles;Sierra McDonald;Sasikanth Manne

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

    Ravi K. Amaravadi;Duonan Yu;Julian J. Lum;Thi Bui

  • Autophagy in malignant transformation and cancer progression

    Lorenzo Galluzzi;Federico Pietrocola;Federico Pietrocola;José Manuel Bravo-San Pedro;José Manuel Bravo-San Pedro;Ravi K. Amaravadi

  • Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade.

    Joseph L. Benci;Bihui Xu;Yu Qiu;Tony J. Wu

  • Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth

    Monica Buzzai;Russell G. Jones;Ravi K. Amaravadi;Julian J. Lum

  • Principles and current strategies for targeting autophagy for cancer treatment.

    Ravi K. Amaravadi;Jennifer Lippincott-Schwartz;Xiao Ming Yin;William A. Weiss

  • Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

    Jean-Christophe Beltra;Sasikanth Manne;Mohamed S. Abdel-Hakeem;Makoto Kurachi

  • Targeting Autophagy in Cancer: Recent Advances and Future Directions

    Ravi K. Amaravadi;Alec C. Kimmelman;Jayanta Debnath

  • Recent insights into the function of autophagy in cancer

    Ravi Amaravadi;Alec C. Kimmelman;Eileen White

  • Targeting autophagy in cancer

    Angelique V. Onorati;Matheus Dyczynski;Rani Ojha;Ravi K. Amaravadi

  • The roles of therapy-induced autophagy and necrosis in cancer treatment.

    Ravi K Amaravadi;Craig B Thompson

  • Enhancing CD8 + T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.

    Ying Zhang;Ying Zhang;Raj Kurupati;Ling Liu;Xiang Yang Zhou

  • A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

    Alexander C. Huang;Robert J. Orlowski;Robert J. Orlowski;Xiaowei Xu;Rosemarie Mick

  • The survival kinases Akt and Pim as potential pharmacological targets.

    Ravi Amaravadi;Craig B. Thompson

  • A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

    Myrna R. Rosenfeld;Xiaobu Ye;Jeffrey G. Supko;Serena Desideri

Frequent Co-Authors

Lynn M. Schuchter
Lynn M. Schuchter University of Pennsylvania
Xiaowei Xu
Xiaowei Xu University of Pennsylvania
Keith T. Flaherty
Keith T. Flaherty Harvard University
Jeffrey D. Winkler
Jeffrey D. Winkler University of Pennsylvania
Wei Xu
Wei Xu Shenzhen University
E. John Wherry
E. John Wherry University of Pennsylvania
Rosemarie Mick
Rosemarie Mick University of Pennsylvania
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Robert H. Vonderheide
Robert H. Vonderheide University of Pennsylvania
Katherine L. Nathanson
Katherine L. Nathanson University of Pennsylvania

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