World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
58
Citations
20567
World Ranking
2056
National Ranking
1023

Overview

Michael A. Tainsky is affiliated with Wayne State University in the United States and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields, including Genetics, Molecular Biology, Cancer Research, Radiology, Nuclear Medicine and Imaging, and Immunology.

Their scholarly work focuses on main topics such as BRCA gene mutations in cancer, Genomics and Rare Diseases, DNA Repair Mechanisms, Cancer Genomics and Diagnostics, Monoclonal and Polyclonal Antibodies Research, Immunotherapy and Immune Responses, and Genetics and Neurodevelopmental Disorders.

Michael A. Tainsky's recent publications include:

  • DNA Repair Mechanisms, Protein Interactions and Therapeutic Targeting of the MRN Complex, 2022, Cancers
  • Evaluation of paraneoplastic antigens reveals TRIM21 autoantibodies as biomarker for early detection of ovarian cancer in combination with autoantibodies to NY-ESO-1 and TP53, 2020, Cancer Biomarkers
  • Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair, 2021, Cell Death Discovery
  • K3326X and Other C-Terminal BRCA2 Variants Implicated in Hereditary Cancer Syndromes: A Review, 2021, Cancers
  • Functional analysis of ATM variants in a high risk cohort provides insight into missing heritability, 2022, Cancer Genetics

Frequent co-authors with whom Michael A. Tainsky has collaborated include:

  • Claire E. McCarthy
  • Scott L. Baughan
  • Fatima Darwiche
  • Nancy K. Levin
  • Russell L. Finley

The scientist's work has been published repeatedly in notable venues such as:

  • Cancers
  • Cancer Genetics
  • Genetics in Medicine Open
  • Cell Death Discovery
  • Cancer Biomarkers

Best Publications

  • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

    David Malkin;Frederick P. Li;Frederick P. Li;Louise C. Strong;Joseph F. Fraumeni

  • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

    Kristina M. Dameron;Olga V. Volpert;Michael A. Tainsky;Noël Bouck

  • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

    Yuxin Yin;Michael A. Tainsky;Farideh Z. Bischoff;Louise C. Strong

  • Molecular cloning of a new transforming gene from a chemically transformed human cell line

    Colin S. Cooper;Morag Park;Donald G. Blair;Michael A. Tainsky

  • Programming gene expression in developing epidermis

    C. Byrne;M. Tainsky;E. Fuchs

  • In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice.

    M. Harvey;A. T. Sands;R. S. Weiss;M. E. Hegi

  • Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle.

    Sylvia C. Dryden;Fatimah A. Nahhas;James E. Nowak;Anton Scott Goustin

  • Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate.

    Sorin Draghici;Purvesh Khatri;Pratik Bhavsar;Abhik Shah

  • Ras gene mutation and amplification in human nonmelanoma skin cancers

    William E. Pierceall;Leonard Harry Goldberg;Michael A. Tainsky;Tapas Mukhopadhyay

  • Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.

    A L Fridman;M A Tainsky

  • Loss of AP‐2 results in downregulation of c‐KIT and enhancement of melanoma tumorigenicity and metastasis

    Suyun Huang;Didier Jean;Mario Luca;Michael A. Tainsky

  • Spontaneous Abnormalities in Normal Fibroblasts from Patients with Li-Fraumeni Cancer Syndrome: Aneuploidy and Immortalization

    Farideh Z. Bischoff;Sun O. Yim;Sen Pathak;Grace Grant

  • Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA.

    Tapas Mukhopadhyay;Michael Tainsky;Adriana C. Cavender;Jack A. Roth

  • Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays

    Madhumita Chatterjee;Saroj Mohapatra;Alexei Ionan;Gagandeep Bawa

  • The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation.

    E N Olson;G Spizz;M A Tainsky

  • Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells

    Didier Jean;Jeffrey E. Gershenwald;Suyun Huang;Mario Luca

  • Breast cancer genetics in African Americans.

    Olufunmilayo I. Olopade;James D. Fackenthal;Georgia Dunston;Michael A. Tainsky

  • Defective G2 Checkpoint Function in Cells from Individuals with Familial Cancer Syndromes

    Richard S. Paules;Eleni N. Levedakou;Sandra J. Wilson;Cynthia L. Innes

  • Stochastic cancer progression driven by non-clonal chromosome aberrations.

    Henry H Q Heng;Joshua B. Stevens;Gou Liu;Steven W. Bremer

  • PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation

    Perry Kannan;Yihong Yu;Sharad Wankhade;Michael A. Tainsky

Frequent Co-Authors

Sorin Draghici
Sorin Draghici Wayne State University
Louise C. Strong
Louise C. Strong The University of Texas MD Anderson Cancer Center
David H. Berger
David H. Berger Harvard University
Waun Ki Hong
Waun Ki Hong The University of Texas MD Anderson Cancer Center
Bruce R. Korf
Bruce R. Korf University of Alabama at Birmingham
Axel Imhof
Axel Imhof Ludwig-Maximilians-Universität München
G. F. Vande Woude
G. F. Vande Woude National Institutes of Health
Lawrence A. Donehower
Lawrence A. Donehower Baylor College of Medicine
Kentaro Hanada
Kentaro Hanada National Institutes of Health
Purvesh Khatri
Purvesh Khatri Stanford University

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