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Biology and Biochemistry

D-Index
62
Citations
12631
World Ranking
10887
National Ranking
839

Overview

Helen R. Griffiths is affiliated with the University of Surrey in the United Kingdom. Their research spans multiple areas within medicine and biochemistry, with a focus on molecular biology, immunology, surgery, and physiology. Griffiths' work is grounded in the exploration of mechanisms underpinning inflammation, oxidative stress, and metabolism.

The scientist's research interests are reflected in their contributions to several key topics, including:

  • Cholesterol and Lipid Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Eicosanoids and Hypertension Pharmacology
  • Antioxidant Activity and Oxidative Stress
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Adipose Tissue and Metabolism
  • Sulfur Compounds in Biology

Griffiths has published extensively in fields related to Medicine and Biochemistry, Genetics and Molecular Biology. Their subfield expertise includes Molecular Biology, Biochemistry, Immunology, Surgery, and Physiology. Frequent publication venues for Griffiths include:

  • Free Radical Biology and Medicine (6 publications)
  • Frontline Gastroenterology (4 publications)
  • Antioxidants and Redox Signaling (2 publications)
  • Redox Biology (2 publications)
  • Journal of Alzheimer's Disease (2 publications)

Notable recent papers authored or co-authored by Griffiths include:

  • "Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation", 2022, Frontiers in Endocrinology
  • "Adipose tissue macrophages as potential targets for obesity and metabolic diseases", 2023, Frontiers in Immunology
  • "Oxidative stress links periodontal inflammation and renal function", 2020, Journal Of Clinical Periodontology
  • "Inflammation, Lipid (Per)oxidation, and Redox Regulation", 2020, Antioxidants and Redox Signaling
  • "Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria", 2021, Journal of Advanced Research

Frequent collaborators in Griffiths' research include Irundika H.K. Dias, Dan Gao, Iain Chapple, Opeyemi Stella Ademowo, and Maria Cristina Polidori, indicating active engagement in interdisciplinary teams addressing oxidative stress, inflammation, and metabolic disease pathways.

Best Publications

  • Vitamin C exhibits pro-oxidant properties

    Ian D. Podmore;Helen R. Griffiths;Karl E. Herbert;Nalini Mistry

  • Monocytes in coronary artery disease and atherosclerosis: where are we now?

    Angie Ghattas;Helen R. Griffiths;Andrew Devitt;Gregory Y.H. Lip;Gregory Y.H. Lip

  • Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.

    Malcolm J. Jackson;Sergio Papa;Juan Bolaños;Richard Bruckdorfer

  • MARK-AGE biomarkers of ageing

    Alexander Bürkle;María Moreno-Villanueva;Jürgen Bernhard;María Blasco

  • Molecular and cellular effects of ultraviolet light-induced genotoxicity.

    Helen R. Griffiths;Pratibha Mistry;Karl E. Herbert;Joseph Lunec

  • Impact of diet composition on blood glucose regulation

    Wendy R Russell;Athanasia Baka;Inger Björck;Nathalie M. Delzenne

  • Novel repair action of vitamin C upon in vivo oxidative DNA damage

    Marcus S Cooke;Mark D Evans;Ian D Podmore;Karl E Herbert

  • Redox regulation in metabolic programming and inflammation.

    Helen R. Griffiths;Dan Gao;Chathyan Pararasa

  • Systemic Reduction in Glutathione Levels Occurs in Patients with Primary Open-Angle Glaucoma

    Doina Gherghel;Helen Rosemary Griffiths;Emma Jane Hilton;Ian Andrew Cunliffe

  • The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species.

    Darren C Phillips;Kevin J Woollard;Helen R Griffiths

  • 8-Hydroxydeoxyguanosine: A marker of oxidative DNA damage in systemic lupus erythematosus

    Joseph Lunec;Karl E. Herbert;Susan Blount;Helen R. Griffiths

  • Plasma Antioxidant Status, Immunoglobulin G Oxidation and Lipid Peroxidation in Demented Patients: Relevance to Alzheimer Disease and Vascular Dementia

    M. Cristina Polidori;Paola Mattioli;Sarah Aldred;Roberta Cecchetti

  • Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk?

    Tracey E Toms;Vasileios F Panoulas;Karen M J Douglas;Helen Griffiths

  • Thiol redox homeostasis in neurodegenerative disease

    Gethin J. McBean;Mutay Aslan;Helen R. Griffiths;Rita C. Torrão

  • The dual role of Reactive Oxygen Species in autoimmune and inflammatory diseases: evidence from preclinical models.

    Markus H. Hoffmann;Helen R. Griffiths

  • Urinary 8-oxo-2'-deoxyguanosine: redox regulation of DNA repair in vivo?

    Joseph Lunec;Karen A Holloway;Marcus S Cooke;Steve Faux

  • Lipid (per) oxidation in mitochondria: an emerging target in the ageing process?

    O.S. Ademowo;H.K.I. Dias;Dominick G.A. Burton;H.R. Griffiths;H.R. Griffiths

  • Ascorbic acid in the 21st century – more than a simple antioxidant

    H R Griffiths;Joseph Lunec

  • The effects of vitamin C supplementation on protein oxidation in healthy volunteers.

    Julie L. Carty;Ruth J. Bevan;Helen Waller;Nalini Mistry

  • Plasma-enhanced chemical vapour deposition growth of Si nanowires with low melting point metal catalysts: an effective alternative to Au-mediated growth

    F. Iacopi;Philippe Vereecken;M. Schaekers;M. Caymax

Frequent Co-Authors

Gregory Y.H. Lip
Gregory Y.H. Lip University of Liverpool
Clifford J. Bailey
Clifford J. Bailey Aston University
Wilhelm Stahl
Wilhelm Stahl Heinrich Heine University Düsseldorf
George D. Kitas
George D. Kitas Dudley Group NHS Foundation Trust
James W. Evans
James W. Evans Iowa State University
Tilman Grune
Tilman Grune University of Potsdam
Patrizia Mecocci
Patrizia Mecocci University of Perugia
Jos A. Bosch
Jos A. Bosch University of Amsterdam
Jacqui A. Shaw
Jacqui A. Shaw University of Leicester
Helmut Sies
Helmut Sies Heinrich Heine University Düsseldorf

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