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D-Index & Metrics

Molecular Biology

D-Index
43
Citations
12143
World Ranking
2950
National Ranking
1407

Overview

Mark Lewandoski is affiliated with the National Institutes of Health in the United States and focuses their research on areas intersecting biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields, including molecular biology, surgery, genetics, gastroenterology, and pulmonary and respiratory medicine.

Their notable research topics include developmental biology and gene regulation, congenital diaphragmatic hernia studies, genomics and chromatin dynamics, congenital heart defects research, congenital gastrointestinal and neural anomalies, gastrointestinal motility and disorders, and digestive system and related health.

Mark Lewandoski's recent publications illustrate a focus on embryonic development, gene regulation, and congenital conditions. Selected papers include:

  • Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function, 2020, eLife
  • Proximo-distal positional information encoded by an Fgf-regulated gradient of homeodomain transcription factors in the vertebrate limb, 2020, Science Advances
  • The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall, 2020, Development
  • Cardiac progenitors instruct second heart field fate through Wnts, 2023, Proceedings of the National Academy of Sciences
  • Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease, 2023, eLife

Their frequent coauthors include Matthew J. Anderson, Subhash Kulkarni, Monalee Saha, Jared Slosberg, and Alpana Singh. These collaborations contribute to a diverse and multidisciplinary research network.

Lewandoski's work has been published multiple times in high-profile venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Differentiation, Science Advances, and Proceedings of the National Academy of Sciences. Their highest publication counts appear in bioRxiv with 4 publications and eLife and Differentiation with 3 each.

Best Publications

  • Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

    Nils-Göran Larsson;Jianming Wang;Hans Wilhelmsson;Anders Oldfors

  • An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination.

    Erik N. Meyers;Mark Lewandoski;Gail R. Martin

  • Conditional control of gene expression in the mouse

    Mark Lewandoski

  • Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

    Xin Sun;Erik N. Meyers;Mark Lewandoski;Gail R. Martin

  • Fgf8 signalling from the AER is essential for normal limb development.

    Mark Lewandoski;Xin Sun;Gail R. Martin

  • Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function.

    K. M. Wassarman;M. Lewandoski;K. Campbell;A. L. Joyner

  • Zp3–cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line

    Mark Lewandoski;Karen Montzka Wassarman;Gail R. Martin

  • Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development.

    Alan O. Perantoni;Olga Timofeeva;Florence Naillat;Charmaine Richman

  • A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation.

    Alexander Aulehla;Winfried Wiegraebe;Valerie Baubet;Matthias B. Wahl

  • Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development

    Xin Sun;Mark Lewandoski;Erik N. Meyers;Yi-Hsin Liu

  • A Huntington's Disease CAG Expansion at the Murine Hdh Locus Is Unstable and Associated with Behavioural Abnormalities in Mice

    Peggy F. Shelbourne;Nigel Killeen;Robert F. Hevner;Heather M. Johnston

  • Analysis of Fgf8 Gene Function in Vertebrate Development

    M Lewandoski;E N Meyers;G R Martin

  • Wnt3a/β-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation

    William C. Dunty;Kristin K. Biris;Ravindra B. Chalamalasetty;Makoto M. Taketo

  • FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis

    Matthias B. Wahl;Chuxia Deng;Mark Lewandoski;Olivier Pourquié;Olivier Pourquié

  • Cre-mediated chromosome loss in mice.

    Mark Lewandoski;Gail R. Martin

  • FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis

    L. A. Naiche;Nakisha Holder;Mark Lewandoski

  • Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea.

    Bonnie E. Jacques;Mireille E. Montcouquiol;Erynn M. Layman;Mark Lewandoski

  • BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling.

    Sangeeta Pajni-Underwood;Catherine P. Wilson;Cindy Elder;Yuji Mishina

  • Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population

    Margot Williams;Carol Burdsal;Ammasi Periasamy;Mark Lewandoski

  • MUSCLE-SPECIFIC CELL ABLATION CONDITIONAL UPON CRE-MEDIATED DNA RECOMBINATION IN TRANSGENIC MICE LEADS TO MASSIVE SPINAL AND CRANIAL MOTONEURON LOSS

    Uta Grieshammer;Mark Lewandoski;David Prevette;Ronald W. Oppenheim

Frequent Co-Authors

Gail R. Martin
Gail R. Martin University of California, San Francisco
Olivier Pourquié
Olivier Pourquié Brigham and Women's Hospital
Chu-Xia Deng
Chu-Xia Deng University of Macau
Gregg Duester
Gregg Duester Sanford Burnham Prebys Medical Discovery Institute
David M. Ornitz
David M. Ornitz Washington University in St. Louis
Frank Costantini
Frank Costantini Columbia University
Yingzi Yang
Yingzi Yang Harvard University
Yuji Mishina
Yuji Mishina University of Michigan–Ann Arbor
Ryoichiro Kageyama
Ryoichiro Kageyama Kyoto University
Brian D. Harfe
Brian D. Harfe University of Florida

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