2026 Brian D. Harfe: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	71	1369	1221	694	605	127	20344

Overview

Brian D. Harfe is affiliated with the University of Florida in the United States. Their research primarily focuses on molecular and developmental biology, with significant contributions to biochemistry, genetics, and medicine.

The main fields of study in their work include:

Biochemistry, Genetics and Molecular Biology
Medicine

Within these, their subfields encompass:

Molecular Biology
Developmental Biology
Pathology and Forensic Medicine
Hepatology
Rheumatology

The research topics they cover frequently are:

Hedgehog Signaling Pathway Studies
Congenital limb and hand anomalies
Developmental Biology and Gene Regulation
Spine and Intervertebral Disc Pathology
TGF-β signaling in diseases
Liver physiology and pathology
Bone and Dental Protein Studies

Recent papers authored or co-authored by Brian D. Harfe include:

Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice, 2022, Developmental Cell
Intervertebral disc repair and regeneration: Insights from the notochord, 2021, Seminars in Cell and Developmental Biology
Loss of BMP2 and BMP4 Signaling in the Dental Epithelium Causes Defective Enamel Maturation and Aberrant Development of Ameloblasts, 2022, International Journal of Molecular Sciences
Sonic Hedgehog is not a limb morphogen but acts as a trigger to specify all digits, 2020, bioRxiv (Cold Spring Harbor Laboratory)
A New Mouse Strain to Study Motoneurons in Pompe Disease, 2020, The FASEB Journal

Brian D. Harfe has published multiple times in the following venues:

bioRxiv (Cold Spring Harbor Laboratory)
Developmental Cell
Seminars in Cell and Developmental Biology
International Journal of Molecular Sciences
The FASEB Journal

Their frequent co-authors include:

Jianjian Zhu
Rashmi Patel
Anna Trofka
Susan Mackem
Claes-Göran Reibring

Best Publications

Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities

Brian D. Harfe;Paul J. Scherz;Sahar Nissim;Hua Tian

1066
Citations
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.

Kunikazu Tsuji;Amitabha Bandyopadhyay;Brian D Harfe;Karen Cox

992
Citations
DNA Mismatch Repair and Genetic Instability

Brian D Harfe;Sue Jinks-Robertson

826
Citations
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

Brian D. Harfe;Michael T. McManus;Jennifer H. Mansfield;Eran Hornstein

783
Citations
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis.

Amitabha Bandyopadhyay;Kunikazu Tsuji;Karen Ann Cox;Brian D Harfe

714
Citations
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression

Jennifer H Mansfield;Brian D Harfe;Brian D Harfe;Robert Nissen;John Obenauer

547
Citations
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development

Eran Hornstein;Jennifer H. Mansfield;Soraya Yekta;Jimmy Kuang-Hsien Hu

538
Citations
Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

Tigwa H. Davis;Trinna L. Cuellar;Selina M. Koch;Allison J. Barker

537
Citations
Degeneration and regeneration of the intervertebral disc: lessons from development.

Lachlan J. Smith;Nandan L. Nerurkar;Kyung-Suk Choi;Brian D. Harfe

511
Citations
Distinct stem cell populations regenerate the follicle and interfollicular epidermis.

Vered Levy;Catherine Lindon;Brian D. Harfe;Bruce A. Morgan

499
Citations
Epidermal stem cells arise from the hair follicle after wounding

Vered Levy;Catherine Lindon;Ying Zheng;Brian D. Harfe

481
Citations
Dicer function is essential for lung epithelium morphogenesis

Kelley S. Harris;Zhen Zhang;Michael T. McManus;Brian D. Harfe

477
Citations
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

Sung Jin Hwang;Peter J. A. Blair;Fiona C. Britton;Kate E. O’Driscoll

451
Citations
MicroRNAs in vertebrate development.

Brian D Harfe

450
Citations
MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse

Francis C. Lynn;Peter Skewes-Cox;Yasuhiro Kosaka;Michael T. McManus

414
Citations
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

Hawon Cho;Young Duk Yang;Jesun Lee;Byeongjoon Lee

411
Citations
Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease

Scott J. Harvey;George Jarad;Jeanette Cunningham;Seth Goldberg

376
Citations
Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells.

Mei Bai;B. Harfe;P. Freimuth

365
Citations
Essential role for Dicer during skeletal muscle development.

Jason R. O'Rourke;Sara A. Georges;Howard R. Seay;Stephen J. Tapscott

362
Citations
Studies on expression and function of the TMEM16A calcium-activated chloride channel.

Fen Huang;Jason R. Rock;Brian D. Harfe;Tong Cheng

345
Citations

Frequent Co-Authors

Michael T. McManus University of California, San Francisco

Clifford J. Tabin Harvard University

Sue Jinks-Robertson Duke University

Andrew P. McMahon University of Southern California

Andrew Fire Stanford University

Rainer Schreiber University of Regensburg

Bruce A. Morgan Saarland University

Kunikazu Tsuji Tokyo Medical and Dental University

Karl Kunzelmann University of Regensburg

Vicki Rosen Harvard University

External Links

Personal website of Brian D. Harfe

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