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Molecular Biology

D-Index
56
Citations
9879
World Ranking
2214
National Ranking
4

Overview

Lajos Haracska is affiliated with the Biological Research Centre in Hungary and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a notable focus on molecular biology and genetics. Their work also spans cancer research, oncology, and molecular medicine.

The scientific topics covered by Haracska's research include:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Mesenchymal Stem Cell Research
  • Ubiquitin and Proteasome Pathways
  • Carcinogens and Genotoxicity Assessment
  • Antibiotic Resistance in Bacteria
  • Evolution and Genetic Dynamics

Haracska has published research papers in several journals, reflecting a focus on molecular and cellular biology as well as microbiology and veterinary sciences. Some recent papers include:

  • ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro, 2025, Nature Microbiology
  • A Regenerative Approach to Canine Osteoarthritis Using Allogeneic, Adipose-Derived Mesenchymal Stem Cells. Safety Results of a Long-Term Follow-Up, 2020, Frontiers in Veterinary Science
  • A Comprehensive Evaluation of the Performance of Prediction Algorithms on Clinically Relevant Missense Variants, 2022, International Journal of Molecular Sciences
  • Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades, 2020, BMC Molecular and Cell Biology
  • The Rad5 Helicase and RING Domains Contribute to Genome Stability through their Independent Catalytic Activities, 2022, Journal of Molecular Biology

Frequent co-authors collaborating with Haracska include:

  • Márton Zsolt Enyedi
  • Gábor Jaksa
  • L. Pintér
  • Ernö Kiss
  • Erda Qorri

Haracska's work has appeared repeatedly in several publication venues, with multiple papers in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Cancers
  • Nature Microbiology
  • Frontiers in Veterinary Science

Best Publications

  • Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions

    Robert E. Johnson;M. Todd Washington;Lajos Haracska;Satya Prakash

  • Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites.

    Lajos Haracska;Ildiko Unk;Robert E. Johnson;Erik Johansson

  • Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η

    Lajos Haracska;Sung-Lim Yu;Robert E. Johnson;Louise Prakash

  • Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression.

    András Blastyák;Lajos Pintér;Ildiko Unk;Louise Prakash

  • Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress.

    Alberto Ciccia;Amitabh V. Nimonkar;Yiduo Hu;Ildiko Hajdu;Ildiko Hajdu

  • Physical and Functional Interactions of Human DNA Polymerase η with PCNA

    Lajos Haracska;Robert E. Johnson;Ildiko Unk;Barbara Phillips

  • Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination

    Ildiko Unk;Ildikó Hajdú;Károly Fátyol;Jerard Hurwitz

  • Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen.

    Ildiko Unk;Ildikó Hajdú;Károly Fátyol;Barnabás Szakál

  • Role of DNA Polymerase η in the Bypass of a (6-4) TT Photoproduct

    Robert E. Johnson;Lajos Haracska;Satya Prakash;Louise Prakash

  • Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae

    Lajos Haracska;Carlos A. Torres-Ramos;Carlos A. Torres-Ramos;Robert E. Johnson;Satya Prakash

  • Interaction with PCNA Is Essential for Yeast DNA Polymerase η Function

    Lajos Haracska;Christine M Kondratick;Ildiko Unk;Satya Prakash

  • Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

    Lajos Haracska;Robert E. Johnson;Ildiko Unk;Barbara B. Phillips

  • Stimulation of DNA Synthesis Activity of Human DNA Polymerase κ by PCNA

    Lajos Haracska;Ildiko Unk;Robert E. Johnson;Barbara B. Phillips

  • Role of yeast Rad5 and its human orthologs, HLTF and SHPRH in DNA damage tolerance.

    Ildiko Unk;Ildikó Hajdú;András Blastyák;Lajos Haracska

  • Role of Double-Stranded DNA Translocase Activity of Human HLTF in Replication of Damaged DNA

    András Blastyák;Ildikó Hajdú;Ildikó Unk;Lajos Haracska

  • Role of human DNA polymerase κ as an extender in translesion synthesis

    Lajos Haracska;Louise Prakash;Satya Prakash

  • Replication past O6-Methylguanine by Yeast and Human DNA Polymerase η

    Lajos Haracska;Satya Prakash;Louise Prakash

  • Yeast Rev1 Protein Is a G Template-specific DNA Polymerase

    Lajos Haracska;Satya Prakash;Louise Prakash

  • Human Ape2 protein has a 3′–5′ exonuclease activity that acts preferentially on mismatched base pairs

    Peter Burkovics;Valeria Szukacsov;Ildiko Unk;Lajos Haracska

  • Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.

    Junjun Chen;Yongxing Ai;Jialiang Wang;Lajos Haracska

Frequent Co-Authors

Louise Prakash
Louise Prakash The University of Texas Medical Branch at Galveston
Satya Prakash
Satya Prakash The University of Texas Medical Branch at Galveston
Robert E. Johnson
Robert E. Johnson The University of Texas Medical Branch at Galveston
Jerard Hurwitz
Jerard Hurwitz Memorial Sloan Kettering Cancer Center
Stephen J. Elledge
Stephen J. Elledge Harvard University
Robert P. P. Fuchs
Robert P. P. Fuchs Centre national de la recherche scientifique, CNRS
Peter M. J. Burgers
Peter M. J. Burgers Washington University in St. Louis
Gábor Tamás
Gábor Tamás University of Szeged
Stephen C. Kowalczykowski
Stephen C. Kowalczykowski University of California, Davis
Erik Johansson
Erik Johansson Umeå University

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