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Immunology

D-Index
47
Citations
8609
World Ranking
4523
National Ranking
2045

Overview

Terrence L. Geiger is affiliated with St. Jude Children's Research Hospital in the United States. Their research spans multiple fields, with a particular focus on medicine and biochemistry, genetics, and molecular biology. Key subfields of study include oncology, molecular biology, immunology, infectious diseases, and hematology.

Geiger's work primarily centers on CAR-T cell therapy research while also encompassing viral infectious diseases, immune cell function, and gene expression. Topics covered in their publications include:

  • CAR-T cell therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • Vaccine Coverage and Hesitancy
  • COVID-19 Clinical Research Studies
  • Virus-based gene therapy research

Their frequent publication venues include:

  • Blood
  • The Journal of Immunology
  • JAMA
  • Blood Advances
  • Current Opinion in Biotechnology

Terrence L. Geiger has coauthored extensively with several researchers, including:

  • Wenting Zheng
  • Jayadev Mavuluri
  • Hongbo Chi
  • Jun Wei
  • Lindsay L. Jones

Notable publications by Geiger include:

  • "Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination in a Routinely Screened Workforce," 2021, JAMA
  • "Regnase-1 suppresses TCF-1+ precursor exhausted T-cell formation to limit CAR-T-cell responses against ALL," 2021, Blood
  • "Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL," 2022, Blood Advances
  • "T cell metabolism in homeostasis and cancer immunity," 2021, Current Opinion in Biotechnology
  • "GPR65 Inactivation in Tumor Cells Drives Antigen-Independent CAR T-cell Resistance via Macrophage Remodeling," 2025, Cancer Discovery

Best Publications

  • Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia

    C. Imai;K. Mihara;M. Andreansky;I. C. Nicholson

  • Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy

    Jun Wei;Lingyun Long;Wenting Zheng;Yogesh Dhungana

  • A Kinetic and Dynamic Analysis of Foxp3 Induced in T Cells by TGF-β

    Ramesh K. Selvaraj;Terrence L. Geiger

  • Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling

    Pim J Koelink;Felicia M Bloemendaal;Bofeng Li;Liset Westera

  • Regulation of ZAP-70 Activation and TCR Signaling by Two Related Proteins, Sts-1 and Sts-2

    Nick Carpino;Steve Turner;Divya Mekala;Yutaka Takahashi

  • PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells.

    Wenting Zheng;Carol E. O’Hear;Carol E. O’Hear;Rajshekhar Alli;Jacob H. Basham

  • IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis.

    Bofeng Li;Rajshekhar Alli;Peter Vogel;Terrence L. Geiger

  • Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

    Prajwal Gurung;Bofeng Li;R. K. Subbarao Malireddi;Mohamed Lamkanfi

  • Acetaminophen and Diphenhydramine Premedication for Allergic and Febrile Nonhemolytic Transfusion Reactions: Good Prophylaxis or Bad Practice?

    Terrence L. Geiger;Scott C. Howard

  • Mitigation of Experimental Allergic Encephalomyelitis by TGF-β Induced Foxp3+ Regulatory T Lymphocytes through the Induction of Anergy and Infectious Tolerance

    Ramesh K. Selvaraj;Terrence L. Geiger

  • Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire

    Phuong Nguyen;Jing Ma;Deqing Pei;Caroline Obert

  • Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes.

    Terrence L. Geiger;Phuong Nguyen;David Leitenberg;Richard A. Flavell

  • Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes.

    Divya J. Mekala;Terrence L. Geiger

  • A large-scale method for the selective depletion of αβ T lymphocytes from PBSC for allogeneic transplantation

    S. Chaleff;M. Otto;R.C. Barfield;T. Leimig

  • IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes.

    Divya J. Mekala;Rajshekhar S. Alli;Terrence L. Geiger

  • Anti-CD33 chimeric antigen receptor targeting of acute myeloid leukemia

    Carol O’Hear;Joshua F. Heiber;Ingo Schubert;Georg Fey

  • Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells

    P R Gordon;T Leimig;A Babarin-Dorner;J Houston

  • IL-6 Promotes T Cell Proliferation and Expansion under Inflammatory Conditions in Association with Low-Level RORγt Expression.

    Bofeng Li;Bofeng Li;Lindsay L. Jones;Terrence L. Geiger

  • A one-step large-scale method for T- and B-cell depletion of mobilized PBSC for allogeneic transplantation

    R.C. Barfield;M. Otto;J. Houston;M. Holladay

  • Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein.

    Scott J. Antonia;Terrence Geiger;Judith Miller;Richard A. Flavell

  • IL-10 modulates DSS-induced colitis through a macrophage -ROS-NO axis (P3254)

    Bofeng Li;Rajshekhar Alli;Peter Vogel;Terrence Geiger

Frequent Co-Authors

Richard A. Flavell
Richard A. Flavell Yale University
Peter Vogel
Peter Vogel St. Jude Children's Research Hospital
Ching-Hon Pui
Ching-Hon Pui St. Jude Children's Research Hospital
Raul C. Ribeiro
Raul C. Ribeiro St. Jude Children's Research Hospital
Scott C. Howard
Scott C. Howard University of Tennessee Health Science Center
Paul G. Thomas
Paul G. Thomas St. Jude Children's Research Hospital
Rupert Handgretinger
Rupert Handgretinger University of Tübingen
Pan Zheng
Pan Zheng University of Maryland, Baltimore
Hongbo Chi
Hongbo Chi St. Jude Children's Research Hospital
Yang Liu
Yang Liu University of Michigan–Ann Arbor

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