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Molecular Biology

D-Index
62
Citations
20990
World Ranking
1833
National Ranking
917

Overview

Shridar Ganesan is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Oncology, Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, and Pathology and Forensic Medicine.

Their work covers a range of topics, with a particular focus on:

  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • RNA modifications and cancer
  • Genetic factors in colorectal cancer
  • Epigenetics and DNA Methylation
  • Breast Cancer Treatment Studies
  • DNA Repair Mechanisms

They have frequently published research in several prominent venues, including:

  • Cancer Research
  • JCO Precision Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cureus
  • Clinical Cancer Research

Notable recent papers by Shridar Ganesan include:

  • Understanding and overcoming resistance to PARP inhibitors in cancer therapy, 2021, Nature Reviews Clinical Oncology
  • Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkers, 2021, ESMO Open
  • Pan-Cancer Analysis of BRCA1 and BRCA2 Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity, 2020, JCO Precision Oncology
  • Emerging strategies for treating metastasis, 2021, Nature Cancer
  • Clinical and Pharmacologic Differences of CDK4/6 Inhibitors in Breast Cancer, 2021, Frontiers in Oncology

Frequent collaborators in their research include Coral Omene, Gregory Riedlinger, Mridula George, Deborah Toppmeyer, and Hossein Khiabanian.

Best Publications

  • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

    Chryssa Kanellopoulou;Stefan A. Muljo;Andrew L. Kung;Shridar Ganesan

  • Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.

    Irene Garcia-Higuera;Toshiyasu Taniguchi;Shridar Ganesan;M.Stephen Meyn

  • 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

    Peter Bouwman;Amal Mahmoud Aly;Jose M. Escandell;Mark Pieterse

  • X chromosomal abnormalities in basal-like human breast cancer

    Andrea L. Richardson;Zhigang C. Wang;Arcangela De Nicolo;Arcangela De Nicolo;Xin Lu

  • BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.

    Sharon B. Cantor;Daphne W. Bell;Shridar Ganesan;Elizabeth M. Kass

  • Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent

    Angel Cruz-Roa;Angel Cruz-Roa;Hannah Leah Gilmore;Ajay Basavanhally;Michael Feldman

  • The telomerase reverse transcriptase regulates chromatin state and DNA damage responses

    Kenkichi Masutomi;Richard Possemato;Judy M. Y. Wong;Jennifer L. Currier

  • Genetic analysis of BRCA1 function in a defined tumor cell line.

    Ralph Scully;Shridar Ganesan;Katerina Vlasakova;Junjie Chen

  • Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.

    Kwok Kin Wong;Sandy Chang;Sarah R. Weiler;Shridar Ganesan

  • BRCA1 Supports XIST RNA Concentration on the Inactive X Chromosome

    Shridar Ganesan;Daniel P. Silver;Roger A. Greenberg;Dror Avni

  • Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns

    A. Rose Brannon;Anupama Reddy;Michael Seiler;Alexandra Arreola

  • Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma

    Huiqing Liu;Angela R Brannon;Anupama R Reddy;Gabriela Alexe

  • Location of BRCA1 in Human Breast and Ovarian Cancer Cells

    Scully R;Ganesan S;Brown M;De Caprio Ja

  • BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

    Vasudeva Ginjala;Karim Nacerddine;Atul Kulkarni;Jay Oza

  • High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates.

    Gabriela Alexe;Gul S. Dalgin;Daniel Scanfeld;Pablo Tamayo

  • Mutational landscape of the essential autophagy gene BECN1 in human cancers.

    Saurabh V. Laddha;Shridar Ganesan;Chang S. Chan;Eileen White

  • Tumorigenesis in mice carrying a truncating Brca1 mutation

    Thomas Ludwig;Peter Fisher;Shridar Ganesan;Argiris Efstratiadis

  • The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

    Shilpy Joshi;Denis Tolkunov;Hana Aviv;Abraham A. Hakimi

  • The disappearing Barr body in breast and ovarian cancers

    Gayle Jeannette Pageau;Lisa L. Hall;Shridar Ganesan;David M. Livingston

  • Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage.

    Dror Avni;Hong Yang;Fabio Martelli;Francesco Hofmann

Frequent Co-Authors

Siraj M. Ali
Siraj M. Ali Foundation Medicine
Anant Madabhushi
Anant Madabhushi Emory University
Jeffrey S. Ross
Jeffrey S. Ross Foundation Medicine
Michael Feldman
Michael Feldman University of Pennsylvania
John E. Tomaszewski
John E. Tomaszewski University at Buffalo, State University of New York
Eileen White
Eileen White Rutgers, The State University of New Jersey
Garrett M. Frampton
Garrett M. Frampton Foundation Medicine
Howard L. Kaufman
Howard L. Kaufman Harvard University
Ronny Drapkin
Ronny Drapkin University of Pennsylvania

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