World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
69
Citations
35687
World Ranking
2310
National Ranking
1042

Overview

Mihael H. Polymeropoulos is affiliated with Vanda Pharmaceuticals in the United States and has an extensive publication record primarily in the field of Medicine. Their research spans several specialized subfields including Endocrine and Autonomic Systems, Physiology, Psychiatry and Mental Health, Gastroenterology, and Infectious Diseases.

The scientist's work encompasses a diverse range of topics, among which are:

  • Circadian rhythm and melatonin
  • Gastrointestinal motility and disorders
  • Dermatology and Skin Diseases
  • Sleep and related disorders
  • Sleep and Wakefulness Research
  • Pathogenesis and Treatment of Hiccups
  • SARS-CoV-2 and COVID-19 Research

Their publication venues reflect a strong focus on biomedical sciences and clinical research. Frequent venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • SLEEP
  • The American Journal of Gastroenterology
  • Frontiers in Neurology

Across their body of work, Mihael H. Polymeropoulos has collaborated most frequently with several coauthors, indicating ongoing research partnerships. Key collaborators include:

  • Gunther Birznieks
  • Changfu Xiao
  • Sandra Smieszek
  • Christos Polymeropoulos
  • Jesse L. Carlin

Selected recent publications provide insight into specific research topics and their evolution over time. These include:

  • "Amantadine disrupts lysosomal gene expression: A hypothesis for COVID19 treatment," 2020, International Journal of Antimicrobial Agents
  • "Efficacy and Safety of Tradipitant in Patients With Diabetic and Idiopathic Gastroparesis in a Randomized, Placebo-Controlled Trial," 2020, Gastroenterology
  • "Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status," 2020, Scientific Reports
  • "Loss-of-function mutations in IFNAR2 in COVID-19 severe infection susceptibility," 2021, Journal of Global Antimicrobial Resistance
  • "Neurokinin-1 receptor antagonist tradipitant has mixed effects on itch in atopic dermatitis: results from EPIONE, a randomized clinical trial," 2020, Journal of the European Academy of Dermatology and Venereology

Best Publications

  • Mutation in the α-synuclein gene identified in families with Parkinson's disease

    Mihael H. Polymeropoulos;Christian Lavedan;Elisabeth Leroy;Susan E. Ide

  • Complementary DNA sequencing : expressed sequence tags and human genome project

    Mark D. Adams;Jenny M. Kelley;Jeannine D. Gocayne;Mark Dubnick

  • The ubiquitin pathway in Parkinson's disease

    Elisabeth Leroy;Rebecca Boyer;Georg Auburger;Barbara Leube

  • The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.

    Greg Lennon;Charles Auffray;Mihael Polymeropoulos;Marcelo Bento Soares

  • Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

    Eugene D. Carstea;Jill A. Morris;Katherine G. Coleman;Stacie K. Loftus

  • Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

    Robert Freedman;Hilary Coon;Marina Myles-Worsley;Avi Orr-Urtreger

  • A gene map of the human genome

    G. D. Schuler;M. S. Boguski;E. A. Stewart;L. D. Stein

  • Mapping of a Gene for Parkinson's Disease to Chromosome 4q21-q23

    Mihael H. Polymeropoulos;Joseph J. Higgins;Lawrence I. Golbe;William G. Johnson

  • A Physical Map of 30,000 Human Genes

    P. Deloukas;G. D. Schuler;G. Gyapay;E. M. Beasley

  • Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis

    Victor L. Ruiz-Perez;Susan E. Ide;Susan E. Ide;Tim M. Strom;Bettina Lorenz

  • Tetranucleotide repeat polymorphism at the human tyrosine hydroxylase gene (TH)

    Mihael H. Polymeropoulos;Hong Xiao;Denise S. Rath;Carl R. Merril

  • Tetranucleotide repeat polymorphism at the human c-fes/fps proto-oncogene (FES).

    Mihael H. Polymeropoulos;Denise S. Rath;Hong Xiao;Carl R. Merril

  • Identification, localization and characterization of the human γ-synuclein gene

    Christian Lavedan;Elisabeth Leroy;Anindya Dehejia;Stephanie Buchholtz

  • Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: two randomised controlled multicentre trials

    Shanthakumar M W Rajaratnam;Shanthakumar M W Rajaratnam;Shanthakumar M W Rajaratnam;Mihael H Polymeropoulos;Dennis M Fisher;Thomas Roth

  • Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

    D Meezaman;P Charles;E Daskal;M H Polymeropoulos

  • Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.

    Stephen B. Gruber;Stephen B. Gruber;Mark M. Entius;Gloria M. Petersen;Steven J. Laken

  • Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21.

    S. B. Patel;G. Salen;H. Hidaka;P. O. Kwiterovich

  • Alpha synuclein in neurodegenerative disorders: murderer or accomplice?

    E. Mezey;A. Dehejia;G. Harta;M.I. Papp

  • Clinical and Molecular Genetic Analysis of 19 Wolfram Syndrome Kindreds Demonstrating a Wide Spectrum of Mutations in WFS1

    Carol Hardy;Farhat Khanim;Rosarelis Torres;Rosarelis Torres;Martin Scott-Brown

  • A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12

    M. Gill;H. Vallada;D. Collier;P. Sham

Frequent Co-Authors

Clair A. Francomano
Clair A. Francomano Indiana University
Robert L. Nussbaum
Robert L. Nussbaum University of California, San Francisco
Jean Weissenbach
Jean Weissenbach Centre national de la recherche scientifique, CNRS
James M. Sikela
James M. Sikela University of Colorado Denver
Kevin G. Becker
Kevin G. Becker National Institutes of Health
David A. Collier
David A. Collier Eli Lilly (United States)
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute
David R. Cox
David R. Cox Stanford University
Charles Auffray
Charles Auffray Centre national de la recherche scientifique, CNRS
William E. Biddison
William E. Biddison National Institutes of Health

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