World's Best Scientists 2026 revealed!

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Medicine

D-Index
131
Citations
73595
World Ranking
2372
National Ranking
1337

Research.com Recognitions

  • 2004 - Member of the National Academy of Medicine (NAM)

Overview

Robert Freedman is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily focuses on medicine, with significant contributions to pediatrics, perinatology, and child health, as well as genetics, public health, environmental and occupational health, molecular biology, and psychiatry and mental health.

The scientist's research topics cover a range of subjects including:

  • Maternal Mental Health During Pregnancy and Postpartum
  • Birth, Development, and Health
  • Genetic Associations and Epidemiology
  • Tryptophan and brain disorders
  • Neonatal and fetal brain pathology
  • Genomics and Rare Diseases
  • Schizophrenia research and treatment

Robert Freedman has contributed to numerous scientific papers, with a selection of recent papers including:

  • "A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts," 2021, in Biological Psychiatry
  • "Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia," 2022, in JAMA Psychiatry
  • "Double blind, two dose, randomized, placebo-controlled, cross-over clinical trial of the positive allosteric modulator at the alpha7 nicotinic cholinergic receptor AVL-3288 in schizophrenia patients," 2020, in Neuropsychopharmacology
  • "P50 inhibitory sensory gating in schizophrenia: analysis of recent studies," 2020, in Schizophrenia Research
  • "Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System," 2022, in JAMA Psychiatry

They have frequently collaborated with several coauthors, including:

  • Sharon K. Hunter (12 joint publications)
  • M. Camille Hoffman (12 joint publications)
  • Amanda J. Law (11 joint publications)
  • Tim B. Bigdeli (10 joint publications)
  • Steven R. Bailey (8 joint publications)

Robert Freedman's work has been published in multiple venues, with notable frequent venues being:

  • Catheterization and Cardiovascular Interventions (8 publications)
  • JAMA Psychiatry (3 publications)
  • Schizophrenia Research (3 publications)
  • Journal of Psychiatric Research (2 publications)
  • Schizophrenia Bulletin (2 publications)

In recognition of their contributions, Robert Freedman was elected as a Member of the National Academy of Medicine in 2004.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

    Robert Freedman;Hilary Coon;Marina Myles-Worsley;Avi Orr-Urtreger

  • Common variants on chromosome 6p22.1 are associated with schizophrenia

    Jianxin Shi;Douglas F. Levinson;Jubao Duan;Alan R. Sanders

  • Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia.

    Lawrence E Adler;E. Pachtman;R. D. Franks;M. Pecevich

  • Identification of loci associated with schizophrenia by genome-wide association and follow-up

    Michael C. O'Donovan;Nicholas Craddock;Nadine Norton;Hywel Williams

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Normalization of Auditory Physiology by Cigarette Smoking in Schizophrenic Patients

    Lawrence E. Adler;Lee D. Hoffer;Anne Wiser;Robert Freedman

  • Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia.

    Robert Freedman;Michael Hall;Lawrence E. Adler;Sherry Leonard

  • Schizophrenia, Sensory Gating, and Nicotinic Receptors

    Lawrence E. Adler;Ann Olincy;Merilyne Waldo;Josette G. Harris

  • Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia.

    Ann Olincy;Josette G. Harris;Lynn L. Johnson;Vicki Pender

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: comparison of medicated and drug-free patients.

    Freedman R;Adler Le;Waldo Mc;Pachtman E

  • Association of Promoter Variants in the α7 Nicotinic Acetylcholine Receptor Subunit Gene With an Inhibitory Deficit Found in Schizophrenia

    Sherry Leonard;Judith Gault;Jan Hopkins;Judith Logel

  • Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up

    Olle Lindvall;Stig Rehncrona;Patrik Brundin;Björn Gustavii

  • Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics.

    Lawrence E. Adler;Lee J. Hoffer;Jay Griffith;Merilyne C. Waldo

  • Deconstructing Schizophrenia: An Overview of the Use of Endophenotypes in Order to Understand a Complex Disorder

    David L. Braff;Robert Freedman;Nicholas J. Schork;Irving I. Gottesman

Frequent Co-Authors

Lawrence E. Adler
Lawrence E. Adler University of Colorado Denver
Jeremy M. Silverman
Jeremy M. Silverman Icahn School of Medicine at Mount Sinai
William Byerley
William Byerley University of California, San Francisco
Larry J. Siever
Larry J. Siever Icahn School of Medicine at Mount Sinai
Larry J. Seidman
Larry J. Seidman Beth Israel Deaconess Medical Center
Ming T. Tsuang
Ming T. Tsuang University of California, San Diego
Allen D. Radant
Allen D. Radant University of Washington
David L. Braff
David L. Braff University of California, San Diego
Gregory A. Light
Gregory A. Light University of California, San Diego
Barry J. Hoffer
Barry J. Hoffer Case Western Reserve University

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