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Keiko Nakayama

Keiko Nakayama

D-Index & Metrics

Molecular Biology

D-Index
70
Citations
20020
World Ranking
1412
National Ranking
119

Overview

Keiko Nakayama is affiliated with Tohoku University in Japan. Their research spans multiple domains within biochemistry, genetics, and molecular biology, with significant contributions to medicine as well. The main subfields of their work include molecular biology, genetics, oncology, neurology, and cell biology.

The scientist's investigations address topics such as epigenetics and DNA methylation, amyotrophic lateral sclerosis research, neurogenetic and muscular disorders research, genetics and neurodevelopmental disorders, RNA modifications and cancer, endoplasmic reticulum stress and disease, and cancer-related gene regulation.

Frequent collaborators in their research efforts include Ryo Funayama, Tadashi Nakagawa, Matsuyuki Shirota, Tetsuya Niihori, and Yoko Aoki.

Key publication venues for their work are:

  • iScience
  • Cell Reports
  • Cancer Science
  • Journal of Human Genetics
  • bioRxiv (Cold Spring Harbor Laboratory)

Selected recent papers authored by or involving Nakayama demonstrate the scope and focus of their research:

  • Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study, 2020, Journal of Epidemiology
  • BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition, 2020, Cancer Research
  • Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis, 2020, Gastroenterology
  • Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation, 2022, Cell Death and Differentiation
  • Wnt5a in cancer-associated fibroblasts promotes colorectal cancer progression, 2021, Biochemical and Biophysical Research Communications

Best Publications

  • Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

    Eri H. Kobayashi;Takafumi Suzuki;Ryo Funayama;Takeshi Nagashima

  • Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

    Kana Miyamoto;Kiyomi Y. Araki;Kazuhito Naka;Fumio Arai

  • Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.

    Masayoshi Yada;Shigetsugu Hatakeyama;Takumi Kamura;Masaaki Nishiyama

  • Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase.

    Gil Bornstein;Joanna Bloom;Danielle Sitry-Shevah;Keiko Nakayama

  • The F-Box Protein Skp2 Participates in c-Myc Proteosomal Degradation and Acts as a Cofactor for c-Myc-Regulated Transcription

    Natalie Von Der Lehr;Sara Johansson;Siqin Wu;Fuad Bahram

  • Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.

    Akiko Takahashi;Naoko Ohtani;Kimi Yamakoshi;Shin Ichi Iida

  • Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase

    Takumi Kamura;Taichi Hara;Masaki Matsumoto;Noriko Ishida

  • Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cδ

    Akitomo Miyamoto;Keiko Nakayama;Hiroyuki Imaki;Sachiko Hirose

  • Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks

    Yosuke Hirotsu;Fumiki Katsuoka;Ryo Funayama;Takeshi Nagashima

  • Skp2-mediated degradation of p27 regulates progression into mitosis.

    Keiko Nakayama;Hiroyasu Nagahama;Yohji A. Minamishima;Satoshi Miyake

  • Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice.

    Tatsuo Furuyama;Kazuko Kitayama;Yuri Shimoda;Minetaro Ogawa

  • The Tohoku Medical Megabank Project: Design and Mission

    Shinichi Kuriyama;Nobuo Yaegashi;Fuji Nagami;Tomohiko Arai

  • Noncanonical Wnt Signaling through G Protein-Linked PKCδ Activation Promotes Bone Formation

    Xiaolin Tu;Kyu Sang Joeng;Keiichi I. Nakayama;Keiko Nakayama

  • p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells

    Akinobu Matsumoto;Shoichiro Takeishi;Tomoharu Kanie;Etsuo Susaki

  • Targeting the p27 E3 ligase SCF Skp2 results in p27and Skp2-mediated cell-cycle arrest and activation of autophagy

    Qing Chen;Weilin Xie;Deborah J. Kuhn;Peter M. Voorhees

  • Gain-of-Function Mutations in RIT1 Cause Noonan Syndrome, a RAS/MAPK Pathway Syndrome

    Yoko Aoki;Tetsuya Niihori;Toshihiro Banjo;Nobuhiko Okamoto

  • p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70.

    Peng Zou;Hiroki Yoshihara;Kentaro Hosokawa;Ikue Tai

  • Cip/Kip cyclin-dependent kinase inhibitors: brakes of the cell cycle engine during development.

    Kei Ichi Nakayama;Keiko Nakayama

  • Human genetic variation database, a reference database of genetic variations in the Japanese population.

    Koichiro Higasa;Noriko Miyake;Jun Yoshimura;Kohji Okamura

  • The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin

    Takanori Hidaka;Eisaku Ogawa;Eri H Kobayashi;Takafumi Suzuki

Frequent Co-Authors

Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Yoko Aoki
Yoko Aoki Tohoku University
Shigeo Kure
Shigeo Kure Tohoku University
Kazuhiko Igarashi
Kazuhiko Igarashi Tohoku University
Yoichi Matsubara
Yoichi Matsubara Tohoku University
Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Michiaki Unno
Michiaki Unno Tohoku University
Nobuo Yaegashi
Nobuo Yaegashi Tohoku University
Kengo Kinoshita
Kengo Kinoshita Tohoku University
Naoto Ishii
Naoto Ishii Tohoku University

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