Masatoshi Kitagawa

Overview

Best Publications

• Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene.

  Y Kotake;T Nakagawa;K Kitagawa;S Suzuki

  1159
  Citations

• Targeted disruption of Skp2 results in accumulation of cyclin E and p27 (Kip1), polyploidy and centrosome overduplication

  Keiko Nakayama;Hiroyasu Nagahama;Yohji A. Minamishima;Masaki Matsumoto

  894
  Citations

• The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2.

  M. Kitagawa;H. Higashi;H.-K. Jung;I. Suzuki-Takahashi

  733
  Citations

• An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

  Masatoshi Kitagawa;Shigetsugu Hatakeyama;Michiko Shirane;Masaki Matsumoto

  728
  Citations

• Evidence that reactive oxygen species do not mediate NF‐κB activation

  Makio Hayakawa;Hiroshi Miyashita;Isao Sakamoto;Masatoshi Kitagawa

  560
  Citations

• Skp2-mediated degradation of p27 regulates progression into mitosis.

  Keiko Nakayama;Hiroyasu Nagahama;Yohji A. Minamishima;Satoshi Miyake

  409
  Citations

• Geranylgeranylated Rho Small GTPase(s) Are Essential for the Degradation of p27Kip1 and Facilitate the Progression from G1 to S Phase in Growth-stimulated Rat FRTL-5 Cells

  Aizan Hirai;Susumu Nakamura;Yoshihiko Noguchi;Tatsuji Yasuda

  357
  Citations

• Down-regulation of p27 Kip1 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing

  Michiko Shirane;Yumiko Harumiya;Noriko Ishida;Aizan Hirai

  334
  Citations

• Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase.

  Kitagawa M;Okabe T;Ogino H;Matsumoto H

  315
  Citations

• Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability.

  Noriko Ishida;Masatoshi Kitagawa;Shigetsugu Hatakeyama;Kei-ichi Nakayama

  298
  Citations

• Cell cycle regulation by long non-coding RNAs

  Masatoshi Kitagawa;Kyoko Kitagawa;Yojiro Kotake;Yojiro Kotake;Hiroyuki Niida

  279
  Citations

• Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1

  Shigetsugu Hatakeyama;Masatoshi Kitagawa;Keiko Nakayama;Michiko Shirane

  253
  Citations

• Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

  Chiharu Uchida;Seiichi Miwa;Kyoko Kitagawa;Takayuki Hattori

  225
  Citations

• Molecular clearance of ataxin-3 is regulated by a mammalian E4

  Masaki Matsumoto;Masayoshi Yada;Shigetsugu Hatakeyama;Hiroshi Ishimoto

  202
  Citations

• A cyclin-dependent kinase inhibitor, butyrolactone I, inhibits phosphorylation of RB protein and cell cycle progression.

  M Kitagawa;H Higashi;I S Takahashi;T Okabe

  168
  Citations

• Ubiquitin‐mediated control of oncogene and tumor suppressor gene products

  Kyoko Kitagawa;Yojiro Kotake;Masatoshi Kitagawa

  168
  Citations

• Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F‐1 after DNA damage

  Yasumichi Inoue;Masatoshi Kitagawa;Yoichi Taya

  157
  Citations

• Phosphorylation of E2F-1 by cyclin A-cdk2.

  Kitagawa M;Higashi H;Suzuki-Takahashi I;Segawa K

  152
  Citations

• Characterization of a Novel Mammalian SUMO-1/Smt3-specific Isopeptidase, a Homologue of Rat Axam, Which Is an Axin-binding Protein Promoting β-Catenin Degradation

  Tamotsu Nishida;Fumie Kaneko;Masatoshi Kitagawa;Hideyo Yasuda

  151
  Citations

• Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.

  Tomoaki Tanaka;Ichiro Tatsuno;Daigaku Uchida;Iku Moroo

  149
  Citations