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Haruhiko Sugimura

Haruhiko Sugimura

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
24674
World Ranking
3322
National Ranking
204

Medicine

D-Index
84
Citations
25285
World Ranking
15125
National Ranking
467

Overview

Haruhiko Sugimura is affiliated with Hamamatsu University in Japan and has a substantial body of research focused primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. The scientist's work extensively covers molecular biology, cancer research, oncology, pulmonary and respiratory medicine, as well as pathology and forensic medicine.

The main research topics addressed by Sugimura include genetic factors in colorectal cancer, cancer-related gene regulation, lung cancer treatments and mutations, cancer genomics and diagnostics, RNA modifications and cancer, cancer, lipids, and metabolism, and cancer-related molecular mechanisms research.

Frequent co-authors with whom Sugimura has collaborated include Yuji Iwashita, Kazuhito Funai, Kazuya Shinmura, Akikazu Kawase, and Hidetaka Yamada. These collaborations suggest a consistent network focused on related areas in cancer and molecular biology.

Sugimura has published multiple papers in various scientific journals, with recent notable works including:

  • "Hereditary diffuse gastric cancer: updated clinical practice guidelines," 2020, The Lancet Oncology
  • "YTHDF1 and YTHDF2 are associated with better patient survival and an inflamed tumor-immune microenvironment in non-small-cell lung cancer," 2021, OncoImmunology
  • "Comprehensive assessment of multiple tryptophan metabolites as potential biomarkers for immune checkpoint inhibitors in patients with non-small cell lung cancer," 2020, Clinical & Translational Oncology
  • "Neoadjuvant immunotherapy or chemoimmunotherapy in non-small cell lung cancer: a systematic review and meta-analysis," 2022, Translational Lung Cancer Research
  • "Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1," 2021, Clinical and Translational Medicine

Publication venues where Sugimura's research is frequently published include Research Square (Research Square), Genes and Environment, BMC Cancer, Cancer Research, and OncoImmunology. These journals reflect the scientist's focus on cancer biology and related biomedical research.

Best Publications

  • Metabolic gene polymorphism frequencies in control populations.

    S. Garte;L. Gaspari;A.K. Alexandrie;C. Ambrosone

  • MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers

    Masahiro Seike;Akiteru Goto;Tetsuya Okano;Tetsuya Okano;Elise D. Bowman

  • Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA

    Takashi Kohno;Kazuya Shinmura;Kazuya Shinmura;Masahiko Tosaka;Masachika Tani

  • Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

    R. F. Souza;R. Appel;J. Yin;S. Wang

  • Activation of Rac1 by a Crk SH3-binding protein, DOCK180

    Etsuko Kiyokawa;Yuko Hashimoto;Shin Kobayashi;Haruhiko Sugimura

  • Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.

    Hiromi Sakamoto;Kimio Yoshimura;Norihisa Saeki

  • Hereditary Diffuse Gastric Cancer: Updated Clinical Practice Guidelines

    Vanessa R. Blair;Maybelle McLeod;Fátima Carneiro;Daniel G. Coit

  • hOGG1 Ser326Cys Polymorphism and Lung Cancer Susceptibility

    H. Sugimura;T. Kohno;K. Wakai;K. Nagura

  • Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin.

    Takahisa Furuta;Takahisa Furuta;Naohito Shirai;Naohito Shirai;Misako Takashima;Misako Takashima;Fang Xiao;Fang Xiao

  • Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk.

    Shunji Kato;Peter G. Shields;Neil E. Caporaso;Robert N. Hoover

  • Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung.

    A Weston;J C Willey;R Modali;H Sugimura

  • Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1.

    Yoshiro Otsuki;Masamitsu Tanaka;Shigeto Yoshii;Nobuko Kawazoe

  • Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex.

    Etsuko Kiyokawa;Yuko Hashimoto;Takeshi Kurata;Haruhiko Sugimura

  • Overexpression of ERK, an EPH Family Receptor Protein Tyrosine Kinase, in Various Human Tumors

    Etsuko Kiyokawa;Setsuo Takai;Masamitsu Tanaka;Toshio Iwase

  • Overexpression of p53 as a possible prognostic factor in human thyroid carcinoma.

    Yoh Dobashi;Atsuhiko Sakamoto;Haruhiko Sugimura;Maria Mernyei

  • Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

    Chiharu Uchida;Seiichi Miwa;Kyoko Kitagawa;Takayuki Hattori

  • Effects of Helicobacter pylori infection on gastric acid secretion and serum gastrin levels in Mongolian gerbils

    Misako Takashima;T Furuta;H Hanai;H Sugimura

  • Predominant Expression of Human Zic in Cerebellar Granule Cell Lineage and Medulloblastoma

    Naoki Yokota;Jun Aruga;Setsuo Takai;Kiyomi Yamada

  • EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas.

    Kazuya Shinmura;Shinji Kageyama;Hong Tao;Tomoyasu Bunai

  • Use of a Cytokine Gene Expression Signature in Lung Adenocarcinoma and the Surrounding Tissue as a Prognostic Classifier

    Masahiro Seike;Nozomu Yanaihara;Elise D. Bowman;Krista A. Zanetti

Frequent Co-Authors

Shoichiro Tsugane
Shoichiro Tsugane International University of Health and Welfare
Curtis C. Harris
Curtis C. Harris National Institutes of Health
Mitsutoshi Setou
Mitsutoshi Setou Hamamatsu University
Peter G. Shields
Peter G. Shields The Ohio State University
Neil E. Caporaso
Neil E. Caporaso National Institutes of Health
Jun Yokota
Jun Yokota National Cancer Centre
Benjamin F. Trump
Benjamin F. Trump University of Maryland, Baltimore
Takashi Kohno
Takashi Kohno National Cancer Centre
Robert N. Hoover
Robert N. Hoover National Institutes of Health
Teruhiko Yoshida
Teruhiko Yoshida National Cancer Research Institute, UK

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