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Kathy D. McCoy

Kathy D. McCoy

D-Index & Metrics

Immunology

D-Index
79
Citations
33393
World Ranking
1660
National Ranking
32

Overview

Kathy D. McCoy is affiliated with the University of Calgary in Canada and has contributed extensively to research in fields related to medicine and biochemistry, genetics, and molecular biology. Their work predominantly spans molecular biology, immunology, oncology, genetics, and physiology, reflecting a broad interdisciplinary approach within health sciences.

The scientist's research focuses heavily on topics related to gut microbiota and health, with additional attention to cancer immunotherapy and biomarkers, immune cell function and interaction, tryptophan and brain disorders, inflammatory bowel disease, immune response and inflammation, as well as Clostridium difficile and Clostridium perfringens research.

Frequent publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the Canadian Association of Gastroenterology
  • Gastroenterology
  • Nature Communications
  • Mucosal Immunology

Notable recent papers authored by or associated with Kathy D. McCoy include:

  • Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy, 2020, Science
  • Intestinal fungi are causally implicated in microbiome assembly and immune development in mice, 2020, Nature Communications
  • Mucosal or systemic microbiota exposures shape the B cell repertoire, 2020, Nature
  • Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression, 2020, Nature Communications
  • Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection, 2020, Cell Host & Microbe

Kathy D. McCoy has collaborated frequently with a number of co-authors, including:

  • Christina Ohland
  • Carolyn A. Thomson
  • Hena R. Ramay
  • Markus B. Geuking
  • Ian A. Lewis

The body of work by Kathy D. McCoy reveals sustained engagement with complex biological systems at the intersection of microbiome science and immune system function, with implications for understanding disease mechanisms and therapeutic strategies.

Best Publications

  • Host microbiota constantly control maturation and function of microglia in the CNS

    Daniel Erny;Anna Lena Hrabě de Angelis;Diego Jaitin;Peter Wieghofer

  • Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

    Janet G. M. Markle;Daniel N. Frank;Steven Mortin-Toth;Charles E. Robertson

  • The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice.

    Premysl Bercik;Emmanuel Denou;Josh Collins;Wendy Jackson

  • The maternal microbiota drives early postnatal innate immune development

    Mercedes Gomez de Agüero;Stephanie C. Ganal-Vonarburg;Tobias Fuhrer;Sandra Rupp

  • The immune geography of IgA induction and function

    Macpherson Aj;McCoy Kd;Johansen Fe;Brandtzaeg P

  • Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy

    Lukas F. Mager;Regula Burkhard;Nicola Pett;Noah C. A. Cooke

  • Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota.

    Karen Smith;Kathy D. McCoy;Andrew J. Macpherson

  • Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

    Markus B. Geuking;Markus B. Geuking;Julia Cahenzli;Julia Cahenzli;Melissa A.E. Lawson;Melissa A.E. Lawson;Derek C.K. Ng

  • Commensal bacteria protect against food allergen sensitization

    Andrew T Stefka;Taylor Feehley;Prabhanshu Tripathi;Ju Qiu

  • Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

    Siegfried Hapfelmeier;Melissa A.E. Lawson;Emma Wetter Slack;Jorum K. Kirundi

  • The Biochemical and Cellular Basis of Cell Proliferation Assays That Use Tetrazolium Salts

    Michael V. Berridge;An S. Tan;Kathy D. McCOY;Rui Wang

  • Resting dendritic cells induce peripheral CD8 + T cell tolerance through PD-1 and CTLA-4

    Hans Christian Probst;Kathy McCoy;Taku Okazaki;Tasuku Honjo

  • Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

    Julia Cahenzli;Yasmin Köller;Madeleine Wyss;Markus B. Geuking

  • Lung microbiota promotes tolerance to allergens in neonates via PD-L1

    Eva S Gollwitzer;Sejal Saglani;Aurélien Trompette;Koshika Yadava

  • Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

    Emma Wetter Slack;Emma Wetter Slack;Siegfried Hapfelmeier;Siegfried Hapfelmeier;Bärbel Stecher;Yuliya Velykoredko

  • Depletion of murine intestinal microbiota: Effects on gut mucosa and epithelial gene expression

    Dag Henrik Reikvam;Alexander Erofeev;Anders Sandvik;Vedrana Grcic

  • Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

    Tina Herbst;Anke Sichelstiel;Corinne Schär;Koshika Yadava

  • Like Will to Like: Abundances of Closely Related Species Can Predict Susceptibility to Intestinal Colonization by Pathogenic and Commensal Bacteria

    Bärbel Stecher;Samuel Chaffron;Rina Käppeli;Siegfried Hapfelmeier

  • Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium

    Sandrine Brugiroux;Markus Beutler;Carina Pfann;Debora Garzetti

  • The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

    Mario M. Zaiss;Alexis Rapin;Luc Lebon;Lalit Kumar Dubey

  • The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

    Maria L. Balmer;Emma Slack;Andrea de Gottardi;Melissa A. E. Lawson

Frequent Co-Authors

Andrew J. Macpherson
Andrew J. Macpherson University of Bern
Nicola L. Harris
Nicola L. Harris Monash University
Rolf M. Zinkernagel
Rolf M. Zinkernagel University of Zurich
Hans Hengartner
Hans Hengartner University of Zurich
Graham Le Gros
Graham Le Gros Malaghan Institute of Medical Research
Bärbel Stecher
Bärbel Stecher Ludwig-Maximilians-Universität München
Benjamin J. Marsland
Benjamin J. Marsland Monash University
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Mathias Heikenwalder
Mathias Heikenwalder German Cancer Research Center
Bruce Beutler
Bruce Beutler The University of Texas Southwestern Medical Center

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