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Immunology
New Zealand
2025

D-Index & Metrics

Immunology

D-Index
52
Citations
10901
World Ranking
4050
National Ranking
4

Research.com Recognitions

  • 2025 - Research.com Immunology in New Zealand Leader Award
  • 2005 - Fellow of the Royal Society of New Zealand

Overview

Graham Le Gros is affiliated with the Malaghan Institute of Medical Research in New Zealand. Their research spans immunology and microbiology, with significant contributions to medicine. The scientist's publications have focused on immunology, infectious diseases, parasitology, dermatology, and molecular biology.

The scientist has contributed notably to several main topics including:

  • IL-33, ST2, and ILC Pathways
  • Parasites and Host Interactions
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Dermatology and Skin Diseases
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies

Frequent coauthors in their work include:

  • Mali Camberis
  • Jodie Chandler
  • Bibek Yumnam
  • Brittany Lavender
  • Samuel I. Old

They have published extensively in the following venues:

  • Nature Immunology
  • Immunology and Cell Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Vaccine
  • Frontiers in Immunology

Some recent papers authored or coauthored by Graham Le Gros include:

  • "Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes" (2021, Nature Immunology)
  • "Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization" (2021, Nature Immunology)
  • "Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps" (2020, Cell Host & Microbe)
  • "Tissue-specific immunity in helminth infections" (2022, Mucosal Immunology)
  • "Basophils promote barrier dysfunction and resolution in the atopic skin" (2021, Journal of Allergy and Clinical Immunology)

Graham Le Gros was awarded the title of Fellow of the Royal Society of New Zealand in 2005.

Best Publications

  • Disruption of the murine IL-4 gene blocks Th2 cytokine responses

    M Kopf;G Le Gros;M Bachmann;M C Lamers

  • Infection of Mice with Mycobacterium bovis–Bacillus Calmette-Guérin (BCG) Suppresses Allergen-induced Airway Eosinophilia

    Klaus Josef Erb;John W. Holloway;Alexandra Sobeck;Heidrun Moll

  • Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells

    Ben Roediger;Ryan Kyle;Kwok Ho Yip;Nital Sumaria;Nital Sumaria

  • Interleukin-4 is required for the induction of lung Th2 mucosal immunity.

    A J Coyle;G Le Gros;C Bertrand;S Tsuyuki

  • Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells

    F Erard;MT Wild;JA Garcia-Sanz;G Le Gros

  • Virus-specific CD8+ cells can switch to interleukin 5 production and induce airway eosinophilia.

    A J Coyle;F Erard;C Bertrand;S Walti

  • The role of CTLA-4 in the regulation of T cell immune responses.

    K D McCoy;G Le Gros

  • Animal Model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus

    Mali Camberis;Graham Le Gros;Joseph Urban

  • Farm exposure in utero may protect against asthma, hay fever and eczema

    J. Douwes;S. Cheng;N. Travier;C. Cohet

  • Differential T cell function and fate in lymph node and nonlymphoid tissues.

    Nicola L. Harris;Victoria Watt;Franca Ronchese;Graham Le Gros

  • Immune Responses of IL‐4, IL‐5, IL‐6 Deficient Mice

    Manfred Kopf;Graham Le Gros;Anthony J. Coyle;Marie Kosco-Vtlbois

  • Association of beta2-adrenergic receptor polymorphisms with severe asthma.

    J W Holloway;P R Dunbar;G A Riley;G M Sawyer

  • PROTECTIVE IMMUNITY TO NEMATODE INFECTION IS INDUCED BY CTLA-4 BLOCKADE

    Kathy McCoy;Mali Camberis;Graham Le Gros

  • The Functional Role of CD8 + T Helper Type 2 Cells

    R A Seder;G G Le Gros

  • ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms

    Tiffany Bouchery;Ryan Kyle;Mali Camberis;Amy Shepherd

  • Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils

    Keunhee Oh;Tao Shen;Graham Le Gros;Booki Min;Booki Min

  • In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

    Nicholas J. Van Panhuys;Shiau Choot Tang;Melanie Prout;Mali Camberis

  • Lifelong farm exposure may strongly reduce the risk of asthma in adults

    J. Douwes;N. Travier;K. Huang;K. Huang;S. Cheng

  • IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.

    Ben Roediger;Ben Roediger;Ryan Kyle;Szun S. Tay;Szun S. Tay;Andrew J. Mitchell;Andrew J. Mitchell

  • CTLA4 ligation attenuates AP‐1, NFAT and NF‐κB activity in activated T cells

    J. Henry Fraser;Mercedes Rincón;Kathy D. McCoy;Graham Le Gros

  • CD80 Costimulation Is Essential for the Induction of Airway Eosinophilia

    Nicola Harris;Robert Peach;Joe Naemura;Peter S. Linsley

Frequent Co-Authors

Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
William E. Paul
William E. Paul National Institute of Allergy and Infectious Diseases
Nicola L. Harris
Nicola L. Harris Monash University
Benjamin J. Marsland
Benjamin J. Marsland Monash University
Barbara Fazekas de St Groth
Barbara Fazekas de St Groth University of Sydney
Kathy D. McCoy
Kathy D. McCoy University of Calgary
Jonathan J. Ewbank
Jonathan J. Ewbank Aix-Marseille University
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
John W. Holloway
John W. Holloway University of Southampton
Manfred Kopf
Manfred Kopf ETH Zurich

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