World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
74
Citations
21021
World Ranking
1225
National Ranking
23

Overview

Jiemin Wong is affiliated with East China Normal University in China, focusing on areas within biochemistry, genetics, and molecular biology. Their research spans multiple subfields including molecular biology, genetics, oncology, epidemiology, and cancer research.

Their work addresses several main topics:

  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Histone Deacetylase Inhibitors Research
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Genetics and Neurodevelopmental Disorders
  • Cancer-related gene regulation

Wong has published extensively with prominent frequent coauthors including Jiwen Li, Yuanyong Huang, Jialun Li, Zhaosu Chen, and Kang Li. The collaborations indicate a consistent network of researchers contributing to related scientific questions.

Their publications feature in several notable venues, with repeated contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • Journal of Biological Chemistry
  • Science Advances

Among recent papers, the following four illustrate the focus and evolution of their research:

  • Class I histone deacetylases (HDAC1-3) are histone lysine delactylases, 2022, Science Advances
  • HBO1 is a versatile histone acyltransferase critical for promoter histone acylations, 2021, Nucleic Acids Research
  • A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association, 2020, Nucleic Acids Research
  • PI3K/AKT inhibition reverses R-CHOP resistance by destabilizing SOX2 in diffuse large B cell lymphoma, 2020, Theranostics

The research contributions include studies on histone modifications, DNA methylation processes, and molecular mechanisms underlying cancer resistance and gene regulation. This demonstrates interdisciplinary interests spanning molecular biology and oncology.

Best Publications

  • NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities

    Yutong Xue;Jiemin Wong;G.Tony Moreno;Mary K. Young

  • A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex.

    Rainer B Lanz;Neil J McKenna;Sergio A Onate;Urs Albrecht

  • Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor

    Hengbin Wang;Zhi-Qing Huang;Li Xia;Qin Feng

  • JHDM2A, a JmjC-Containing H3K9 Demethylase, Facilitates Transcription Activation by Androgen Receptor

    Kenichi Yamane;Charalambos Toumazou;Yu ichi Tsukada;Hediye Erdjument-Bromage

  • Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3.

    Jiwen Li;Jin Wang;Jianxiang Wang;Zafar Nawaz

  • The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

    Robert J. Klose;Kenichi Yamane;Kenichi Yamane;Yangjin Bae;Dianzheng Zhang

  • Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

    Jiancong Liang;Ma Wan;Yi Zhang;Peili Gu;Peili Gu

  • Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

    Ho-Geun Yoon;Doug W. Chan;Zhi-Qing Huang;Jiwen Li

  • Regulation of the p300 HAT domain via a novel activation loop

    Paul R Thompson;Paul R Thompson;Dongxia Wang;Ling Wang;Marcella Fulco

  • N-CoR Mediates DNA Methylation-Dependent Repression through a Methyl CpG Binding Protein Kaiso.

    Ho Geun Yoon;Doug W. Chan;Albert B. Reynolds;Jun Qin

  • Relationship between Histone H3 Lysine 9 Methylation, Transcription Repression, and Heterochromatin Protein 1 Recruitment

    M. David Stewart;Jiwen Li;Jiemin Wong

  • Selective Phosphorylations of the SRC-3/AIB1 Coactivator Integrate Genomic Reponses to Multiple Cellular Signaling Pathways

    Ray-Chang Wu;Jun Qin;Ping Yi;Jiemin Wong

  • UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

    Xiaoli Liu;Qinqin Gao;Pishun Li;Qian Zhao

  • Progesterone and Glucocorticoid Receptors Recruit Distinct Coactivator Complexes and Promote Distinct Patterns of Local Chromatin Modification

    Xiaotao Li;Jiemin Wong;Sophia Y. Tsai;Ming-Jer Tsai

  • The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis

    Junjiang Fu;Li Qin;Tao He;Jun Qin

  • Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase

    Ray-Chang Wu;Jun Qin;Yoshihiro Hashimoto;Jiemin Wong

  • ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation.

    Panagiota Karagianni;Larbi Amazit;Larbi Amazit;Jun Qin;Jiemin Wong

  • HDAC3: taking the SMRT-N-CoRrect road to repression

    P Karagianni;J Wong;J Wong

  • Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2.

    Serge Grégoire;Lin Xiao;Jianyun Nie;Xiaohong Zhang

  • A role for nucleosome assembly in both silencing and activation of the Xenopus TR beta A gene by the thyroid hormone receptor.

    Jiemin Wong;Yun-Bo Shi;Alan P. Wolffe

Frequent Co-Authors

Jun Qin
Jun Qin Baylor College of Medicine
Bert W. O'Malley
Bert W. O'Malley Baylor College of Medicine
Sophia Y. Tsai
Sophia Y. Tsai Baylor College of Medicine
Ming-Jer Tsai
Ming-Jer Tsai Baylor College of Medicine
Alan P. Wolffe
Alan P. Wolffe Sangamo BioSciences (United States)
Yi Zhang
Yi Zhang Harvard University
Philip A. Cole
Philip A. Cole Brigham and Women's Hospital
Philippe Bouvet
Philippe Bouvet École Normale Supérieure de Lyon
Jing-Dong J. Han
Jing-Dong J. Han Peking University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences

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