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Microbiology

D-Index
87
Citations
26447
World Ranking
799
National Ranking
369

Medicine

D-Index
86
Citations
26496
World Ranking
14146
National Ranking
7167

Overview

James J. Pestka is affiliated with Michigan State University in the United States. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology.

Their subfields of study include Immunology, Nutrition and Dietetics, Molecular Biology, Rheumatology, and Biochemistry.

The main topics of Pestka's work focus on:

  • Fatty Acid Research and Health
  • Systemic Lupus Erythematosus Research
  • Eicosanoids and Hypertension Pharmacology
  • Immune Response and Inflammation
  • Inflammasome and immune disorders
  • T-cell and B-cell Immunology
  • Immune cells in cancer

Key publications by James J. Pestka include:

  • Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice, 2020, Nutrients
  • Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice, 2020, Autoimmunity
  • Rapid Induction of Pulmonary Inflammation, Autoimmune Gene Expression, and Ectopic Lymphoid Neogenesis Following Acute Silica Exposure in Lupus-Prone Mice, 2021, Frontiers in Immunology
  • Fetal Liver-Derived Alveolar-like Macrophages: A Self-Replicating Ex Vivo Model of Alveolar Macrophages for Functional Genetic Studies, 2022, ImmunoHorizons
  • Omega-3 Polyunsaturated Fatty Acid Intervention Against Established Autoimmunity in a Murine Model of Toxicant-Triggered Lupus, 2021, Frontiers in Immunology

Frequent publication venues include:

  • Frontiers in Immunology
  • Autoimmunity
  • Inhalation Toxicology
  • Current Developments in Nutrition
  • bioRxiv (Cold Spring Harbor Laboratory)

Among frequent coauthors collaborating with Pestka are:

  • Kathryn A. Wierenga
  • Jack R. Harkema
  • Abby D. Benninghoff
  • Ryan P. Lewandowski
  • Lichchavi D. Rajasinghe

Best Publications

  • Toxicology of deoxynivalenol (vomitoxin).

    Barbara A. Rotter;Dan B. Prelusky;James J. Pestka

  • Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance.

    James J. Pestka

  • Deoxynivalenol: Toxicology and Potential Effects on Humans

    James J. Pestka;Alexa T. Smolinski

  • Lactobacilli Differentially Modulate Expression of Cytokines and Maturation Surface Markers in Murine Dendritic Cells

    Hanne R. Christensen;Hanne Frøkiær;James J. Pestka

  • Immunomodulation by fungal toxins.

    Genevieve S. Bondy;James J. Pestka

  • Deoxynivalenol: Toxicity, mechanisms and animal health risks

    James J. Pestka

  • Public Health Impacts of Foodborne Mycotoxins

    Felicia Wu;John D. Groopman;James J. Pestka

  • Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox

    James J. Pestka;Hui Ren Zhou;Y. Moon;Y. J. Chung

  • Mechanisms of deoxynivalenol-induced gene expression and apoptosis

    James J. Pestka

  • Apoptosis induction by the satratoxins and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and SAPK/JNK activation.

    Gi Hyeok Yang;Bruce B. Jarvis;Yong Joo Chung;Yong Joo Chung;James J. Pestka

  • Toxicological mechanisms and potential health effects of deoxynivalenol and nivalenol.

    J. J. Pestka

  • Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae

    James J. Pestka

  • Growth and Viability of Commercial Bifidobacterium spp in Skim Milk Containing Oligosaccharides and Inulin

    H.-S. Shin;J.-H. Lee;J.J. Pestka;Z. Ustunol

  • Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin.

    Hui Ren Zhou;Zahidul Islam;James J. Pestka

  • Role of Double-Stranded RNA-Activated Protein Kinase R (PKR) in Deoxynivalenol-Induced Ribotoxic Stress Response

    Hui Ren Zhou;Allan S. Lau;James J. Pestka

  • Effects of 8-week exposure of the B6C3F1 mouse to dietary deoxynivalenol (vomitoxin) and zearalenone.

    J.H. Forsell;M.F. Witt;J.-H. Tai;R. Jensen

  • Stachybotrys chartarum, Trichothecene Mycotoxins, and Damp Building-Related Illness: New Insights into a Public Health Enigma

    James J. Pestka;Iwona Yike;Dorr Gellatly Dearborn;Marsha D W Ward

  • Induction of Cytokine mRNAs in Mice After Oral Exposure to the Trichothecene Vomitoxin (Deoxynivalenol): Relationship to Toxin Distribution and Protein Synthesis Inhibition

    Juan I. Azcona-Olivera;Yanli Ouyang;Jill Murtha;Fun Sun Chu

  • Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 (ginseng) and parthenolide (feverfew)

    Alexa T Smolinski;James J Pestka

  • Alteration of immune function following dietary mycotoxin exposure

    James J. Pestka;Genevieve S. Bondy

Frequent Co-Authors

Jack R. Harkema
Jack R. Harkema Michigan State University
Andrij Holian
Andrij Holian University of Montana
Adam L. Lock
Adam L. Lock Michigan State University
Quan Zhen Li
Quan Zhen Li The University of Texas Southwestern Medical Center
John E. Linz
John E. Linz Michigan State University
Jørn A. Holme
Jørn A. Holme Norwegian Institute of Public Health
Ormond A. MacDougald
Ormond A. MacDougald University of Michigan–Ann Arbor
Susan P. McCormick
Susan P. McCormick United States Department of Agriculture
Randolph M. Beaudry
Randolph M. Beaudry Michigan State University
Brent A. Coull
Brent A. Coull Harvard University

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