World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
10625
World Ranking
8902
National Ranking
3955

Overview

Andrij Holian is affiliated with the University of Montana in the United States and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work crosses multiple subfields including molecular biology, immunology, health, toxicology and mutagenesis, physiology, and materials chemistry.

Their publication record highlights significant contributions related to inflammasome and immune disorders, air quality and health impacts, IL-33, ST2, and ILC pathways, nanoparticles synthesis and applications, lipid membrane structure and behavior, calcium signaling and nucleotide metabolism, and streptococcal infections and treatments.

Frequent co-authors collaborating with Holian include Rebekah L. Kendall, Raymond F. Hamilton, Britten Postma, Matthew J. Sydor, and Zahra Mahdieh.

Holian's research has been published in various scientific venues, including multiple contributions to Inhalation Toxicology, the Journal of Applied Polymer Science, Toxicological Sciences, Colloids and Surfaces B Biointerfaces, and ACS Applied Polymer Materials. The breadth of publications demonstrates an interdisciplinary approach to health and molecular sciences.

Notable recent papers include:

  • Molecular recognition between membrane epitopes and nearly free surface silanols explains silica membranolytic activity, 2022, Colloids and Surfaces B Biointerfaces
  • The role of lysosomal ion channels in lysosome dysfunction, 2021, Inhalation Toxicology
  • Core-Shell Electrospun Fibers with an Improved Open Pore Structure for Size-Controlled Delivery of Nanoparticles, 2020, ACS Applied Polymer Materials
  • Contribution of Particle-Induced Lysosomal Membrane Hyperpolarization to Lysosomal Membrane Permeabilization, 2021, International Journal of Molecular Sciences
  • Multinucleated giant cell phenotype in response to stimulation, 2020, Immunobiology

Best Publications

  • Silica binding and toxicity in alveolar macrophages.

    Raymond F. Hamilton;Sheetal A. Thakur;Andrij Holian

  • Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity

    Raymond F Hamilton;Nianqiang Wu;Dale Porter;Mary Buford

  • Expression of TNF and the necessity of TNF receptors in bleomycin-induced lung injury in mice.

    Luis A. Ortiz;Joseph Lasky;Raymond F. Hamilton;Andrij Holian

  • Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium.

    Tian Xia;Raymond F. Hamilton;James C. Bonner;Edward D. Crandall

  • Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages

    Rashi Iyer;Raymond F. Hamilton;Li Li;Andrij Holian

  • MARCO Mediates Silica Uptake and Toxicity in Alveolar Macrophages from C57BL/6 Mice

    Raymond F. Hamilton;Sheetal A. Thakur;Jolene K. Mayfair;Andrij Holian

  • Control of mitochondrial respiration: a quantitative evaluation of the roles of cytochrome c and oxygen.

    David F. Wilson;Charles S. Owen;Andrij Holian

  • Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology

    Raymond F Hamilton;Zheqiong Wu;Somenath Mitra;Pamela K Shaw

  • Ozone-induced Increases in Substance P and 8-Epi-Prostaglandin F2α in the Airways of Human Subjects

    Munir E. Hazbun;Raymond Hamilton;Andrij Holian;William L. Eschenbacher

  • Transmembrane electrical and pH gradients across human erythrocytes and human peripheral lymphocytes.

    C. J. Deutsch;A. Holian;S. K. Holian;R. P. Daniele

  • Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells.

    Sandra M. Wells;Andrij Holian

  • Control of respiration in isolated mitochondria: quantitative evaluation of the dependence of respiratory rates on [ATP], [ADP], and [Pi].

    Andrij Holian;Charles S. Owen;David F. Wilson

  • Critical Role of MARCO in Crystalline Silica–Induced Pulmonary Inflammation

    Sheetal A. Thakur;Celine A. Beamer;Christopher T. Migliaccio;Andrij Holian

  • A comparison of dispersing media for various engineered carbon nanoparticles

    Mary C Buford;Raymond F Hamilton;Andrij Holian

  • Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: protection at the progenitor cell level.

    S Vadhan-Raj;H E Broxmeyer;W N Hittelman;N E Papadopoulos

  • Bleomycin stimulation of cytokine secretion by the human alveolar macrophage.

    R. K. Scheule;R. C. Perkins;R. Hamilton;A. Holian

  • Silica accelerated systemic autoimmune disease in lupus-prone New Zealand mixed mice

    J M Brown;A J Archer;J C Pfau;A Holian

  • Silica-Directed Mast Cell Activation Is Enhanced by Scavenger Receptors

    Jared M. Brown;Emily J. Swindle;Nataliya M. Kushnir-Sukhov;Andrij Holian

  • Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure

    Celine A Beamer;Andrij Holian

  • Acrolein-Induced Cell Death In Human Alveolar Macrophages☆

    Li Li;Raymond F. Hamilton;David E. Taylor;Andrij Holian

Frequent Co-Authors

Ronald K. Scheule
Ronald K. Scheule Sanofi (United States)
Nianqiang Wu
Nianqiang Wu University of Massachusetts Amherst
Somenath Mitra
Somenath Mitra New Jersey Institute of Technology
Jack R. Harkema
Jack R. Harkema Michigan State University
James J. Pestka
James J. Pestka Michigan State University
David F. Wilson
David F. Wilson University of Pennsylvania
Vincent Castranova
Vincent Castranova West Virginia University
Kent E. Pinkerton
Kent E. Pinkerton University of California, Davis
Carol Deutsch
Carol Deutsch University of Pennsylvania
Mauricio Terrones
Mauricio Terrones Pennsylvania State University

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