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Biology and Biochemistry

D-Index
51
Citations
7729
World Ranking
17329
National Ranking
7123

Overview

Carol Deutsch is affiliated with the University of Pennsylvania in the United States and conducts research primarily in the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their work spans several subfields, including Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience, and Organic Chemistry.

Their research topics include RNA and protein synthesis mechanisms, ion channel regulation and function, cardiac electrophysiology and arrhythmias, bacterial genetics and biotechnology, neuroscience and neuropharmacology research, protein structure and dynamics, and biochemical and molecular research.

Deutsch has published extensively in a variety of scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemistry
  • The Journal of General Physiology
  • Journal of Molecular Biology
  • Biopolymers

Their list of recent papers illustrates a focus on biochemical mechanisms and ion channel physiology:

  • "Molecular rearrangements in S6 during slow inactivation in Shaker-IR potassium channels" (2023), The Journal of General Physiology
  • "Ribosome Elongation Kinetics of Consecutively Charged Residues Are Coupled to Electrostatic Force" (2021), Biochemistry
  • "The activation gate controls steady-state inactivation and recovery from inactivation in Shaker" (2020), The Journal of General Physiology
  • "Side-chain thioamides as fluorescence quenching probes" (2020), Biopolymers
  • "Ribosome elongation kinetics of consecutively charged residues are coupled to electrostatic force" (2021), bioRxiv (Cold Spring Harbor Laboratory)

Collaborative work is an important aspect of Deutsch's career. Frequent coauthors include:

  • Sarah E. Leininger
  • Edward P. O'Brien
  • Aaron Sykes
  • Judith Rodríguez
  • Quyen V. Vu

Best Publications

  • Electrostatics in the Ribosomal Tunnel Modulate Chain Elongation Rates

    Jianli Lu;Carol Deutsch

  • K channels in T lymphocytes: a patch clamp study using monoclonal antibody adhesion.

    D. R. Matteson;C. Deutsch

  • Folding zones inside the ribosomal exit tunnel.

    Jianli Lu;Carol Deutsch

  • Charybdotoxin inhibits proliferation and interleukin 2 production in human peripheral blood lymphocytes

    M Price;S C Lee;C Deutsch

  • Heterologous expression of specific K+ channels in T lymphocytes: functional consequences for volume regulation.

    Carol Deutsch;Li-Qiong Chen

  • C-type inactivation of a voltage-gated K+ channel occurs by a cooperative mechanism

    G. Panyi;Z. Sheng;C. Deutsch

  • Voltage‐gated potassium conductance in human T lymphocytes stimulated with phorbol ester.

    C Deutsch;D Krause;S C Lee

  • Tertiary interactions within the ribosomal exit tunnel

    Andrey Kosolapov;Carol Deutsch

  • Recovery from C-type inactivation is modulated by extracellular potassium

    D.I. Levy;C. Deutsch

  • Metabolic changes in activated T cells : an NMR study of human peripheral blood lymphocytes

    Michal Bental;Carol Deutsch

  • Transmembrane electrical and pH gradients across human erythrocytes and human peripheral lymphocytes.

    C. J. Deutsch;A. Holian;S. K. Holian;R. P. Daniele

  • Potassium Channel Ontogeny

    Carol Deutsch

  • Mapping the electrostatic potential within the ribosomal exit tunnel.

    Jianli Lu;William R. Kobertz;Carol Deutsch

  • Pegylation: a method for assessing topological accessibilities in Kv1.3.

    Jianli Lu;Carol Deutsch

  • Secondary structure formation of a transmembrane segment in Kv channels.

    Jianli Lu;Carol Deutsch

  • Evidence for voltage modulation of IL-2 production in mitogen-stimulated human peripheral blood lymphocytes.

    B D Freedman;M A Price;C J Deutsch

  • The birth of a channel.

    Carol Deutsch

  • Voltage-gated K+ channels contain multiple intersubunit association sites.

    Li Wei Tu;Vincent Santarelli;Zu Fang Sheng;William Skach

  • Cyclic AMP directly inhibits IL-2 receptor expression in human T cells: expression of both p55 and p75 subunits is affected.

    D S Krause;C Deutsch

  • Dependence of gluconeogenesis, urea synthesis, and energy metabolism of hepatocytes on intracellular pH.

    T Kashiwagura;C J Deutsch;J Taylor;M Erecińska

Frequent Co-Authors

David F. Wilson
David F. Wilson University of Pennsylvania
Maria Erecińska
Maria Erecińska University of Pennsylvania
William R. Skach
William R. Skach Cystic Fibrosis Foundation
Kenneth B. Wiberg
Kenneth B. Wiberg Yale University
Andrij Holian
Andrij Holian University of Montana
Michael B. Prystowsky
Michael B. Prystowsky Albert Einstein College of Medicine
Diane S. Krause
Diane S. Krause Yale University
Benoît Roux
Benoît Roux University of Chicago
Arthur E. Johnson
Arthur E. Johnson Texas A&M University
Matthew S. Sachs
Matthew S. Sachs Texas A&M University

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