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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11625
World Ranking
13839
National Ranking
481

Overview

James Ellis is affiliated with the University of Toronto in Canada and focuses research primarily within Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Genetics, Cancer Research, Cellular and Molecular Neuroscience, and Cognitive Neuroscience.

Their main topics of study encompass:

  • Genetics and Neurodevelopmental Disorders
  • RNA modifications and cancer
  • RNA Research and Splicing
  • MicroRNA in disease regulation
  • Pluripotent Stem Cells Research
  • Autism Spectrum Disorder Research
  • RNA Interference and Gene Delivery

Recent publications by James Ellis include the following:

  • Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome, 2020, Cell Reports
  • Multielectrode Arrays for Functional Phenotyping of Neurons from Induced Pluripotent Stem Cell Models of Neurodevelopmental Disorders, 2022, Biology
  • Machine Learning Identifies Clinical and Genetic Factors Associated With Anthracycline Cardiotoxicity in Pediatric Cancer Survivors, 2020, JACC CardioOncology
  • Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies, 2022, Cell Reports
  • Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells, 2020, Nature Communications

They frequently publish in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Communications
  • Translational Psychiatry
  • UNC Libraries

Frequent co-authors collaborating with James Ellis include Marat Mufteev, Deivid C. Rodrigues, Alina Piekna, Wei Wei, and Seema Mital, indicating a consistent multi-disciplinary research network.

Best Publications

  • Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines.

    Steven J. Kattman;Alec D. Witty;Alec D. Witty;Mark Gagliardi;Nicole C. Dubois

  • Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy

    Robert Pawliuk;Karen A. Westerman;Mary E. Fabry;Emmanuel Payen

  • A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

    Masoud Vedadi;Dalia Barsyte-Lovejoy;Feng Liu;Sylvie Rival-Gervier

  • Silencing and variegation of gammaretrovirus and lentivirus vectors

    James Ellis

  • Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein.

    Amy P Wong;Christine E Bear;Stephanie Chin;Peter Pasceri

  • MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

    Hong Han;Manuel Irimia;P. Joel Ross;Hoon Ki Sung

  • Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency

    Akitsu Hotta;Aaron Y L Cheung;Natalie Farra;Kausalia Vijayaragavan;Kausalia Vijayaragavan

  • Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

    Aaron Y.L. Cheung;Lindsay M. Horvath;Daria Grafodatskaya;Peter Pasceri

  • A dominant chromatin-opening activity in 5′ hypersensitive site 3 of the human beta-globin locus control region.

    J. Ellis;K. C. Tan-Un;A. Harper;D. Michalovich

  • A vertebrate Polycomb response element governs segmentation of the posterior hindbrain.

    Angela Sing;Dylan Pannell;Angelo Karaiskakis;Kendra Sturgeon;Kendra Sturgeon

  • Orexin-1 Receptor-Cannabinoid CB1 Receptor Heterodimerization Results in Both Ligand-dependent and -independent Coordinated Alterations of Receptor Localization and Function

    James Ellis;John D. Pediani;Meritxell Canals;Sandra Milasta

  • Silencing of gene expression: implications for design of retrovirus vectors.

    Dylan Pannell;James Ellis

  • Retroviral vector silencing during iPS cell induction: an epigenetic beacon that signals distinct pluripotent states.

    Akitsu Hotta;James Ellis

  • Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code

    Dylan Pannell;Cameron S. Osborne;Shuyuan Yao;Tanya Sukonnik

  • Open and closed domains in the mouse genome are configured as 10‐nm chromatin fibres

    Eden Fussner;Mike Strauss;Ugljesa Djuric;Ren Li

  • Constitutive heterochromatin reorganization during somatic cell reprogramming

    Eden Fussner;Ugljesa Djuric;Mike Strauss;Akitsu Hotta

  • Retrovirus Silencing, Variegation, Extinction, and Memory Are Controlled by a Dynamic Interplay of Multiple Epigenetic Modifications *

    Shuyuan Yao;Tanya Sukonnik;Tara Kean;Rikki R. Bharadwaj

  • Synthetic human beta-globin 5'HS2 constructs function as locus control regions only in multicopy transgene concatamers.

    James Ellis;D. Talbot;Niall Dillon;Frank Grosveld

  • High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors.

    Francois Moreau-Gaudry;Ping Xia;Ping Xia;Gang Jiang;Gang Jiang;Natalya P. Perelman

  • SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons

    Kirill Zaslavsky;Wen-Bo Zhang;Fraser P. McCready;Deivid C. Rodrigues

Frequent Co-Authors

Stephen W. Scherer
Stephen W. Scherer University of Toronto
Akitsu Hotta
Akitsu Hotta Kyoto University
William L. Stanford
William L. Stanford Ottawa Hospital
Andras Nagy
Andras Nagy Lunenfeld-Tanenbaum Research Institute
Michael W. Salter
Michael W. Salter University of Toronto
Benjamin J. Blencowe
Benjamin J. Blencowe University of Toronto
Frank Grosveld
Frank Grosveld Erasmus University Rotterdam
Philippe Leboulch
Philippe Leboulch Brigham and Women's Hospital
Nuno L. Barbosa-Morais
Nuno L. Barbosa-Morais University of Lisbon
David P. Bazett-Jones
David P. Bazett-Jones University of Calgary

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