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Immunology

D-Index
53
Citations
17673
World Ranking
3932
National Ranking
266

Research.com Recognitions

  • 2019 - Member of Academia Europaea

Overview

Hedda Wardemann is affiliated with the German Cancer Research Center in Germany. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant body of work published across various subfields including Immunology, Public Health, Environmental and Occupational Health, Infectious Diseases, Epidemiology, and Radiology, Nuclear Medicine and Imaging.

The main topics covered in Wardemann's research include:

  • Malaria Research and Control
  • T-cell and B-cell Immunology
  • Monoclonal and Polyclonal Antibodies Research
  • SARS-CoV-2 and COVID-19 Research
  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • Trypanosoma species research and implications

Wardemann's frequent co-authors reflect ongoing collaborations and include:

  • Rajagopal Murugan
  • Giulia Costa
  • Katherine Prieto
  • Elena A. Levashina
  • Jean-Philippe Julien

Key publication venues for Wardemann's scientific papers include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature
  • Immunity

Wardemann has contributed to numerous recent papers, among which are the following:

  • ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies, 2020, Nature
  • Parallelism of intestinal secretory IgA shapes functional microbial fitness, 2021, Nature
  • Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs, 2020, Nature Medicine
  • High microbiota reactivity of adult human intestinal IgA requires somatic mutations, 2020, The Journal of Experimental Medicine
  • IGLV3-21 01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling, 2020, Proceedings of the National Academy of Sciences

In 2019, Wardemann was recognized as a Member of Academia Europaea, an award denoting fellowship in this European academy.

Best Publications

  • Predominant Autoantibody Production by Early Human B Cell Precursors

    Hedda Wardemann;Sergey Yurasov;Sergey Yurasov;Anne Schaefer;James W. Young

  • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

    Thomas Tiller;Eric Meffre;Sergey Yurasov;Sergey Yurasov;Makoto Tsuiji

  • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

    Johannes F. Scheid;Hugo Mouquet;Niklas Feldhahn;Michael S. Seaman

  • Visualizing dendritic cell networks in vivo.

    Randall L Lindquist;Guy Shakhar;Diana Dudziak;Hedda Wardemann

  • Defective B cell tolerance checkpoints in systemic lupus erythematosus

    Sergey Yurasov;Hedda Wardemann;Johanna Hammersen;Makoto Tsuiji

  • The promise and challenge of high-throughput sequencing of the antibody repertoire.

    George Georgiou;Gregory C Ippolito;John Beausang;Christian E Busse

  • Autoreactivity in Human IgG+ Memory B Cells

    Thomas Tiller;Makoto Tsuiji;Sergey Yurasov;Klara Velinzon

  • Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

    Marcus Dühren-von Minden;Rudolf Übelhart;Dunja Schneider;Thomas Wossning

  • Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

    Hugo Mouquet;Johannes F. Scheid;Johannes F. Scheid;Markus J. Zoller;Michelle Krogsgaard

  • Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

    Maxime Hervé;Kai Xu;Yen Shing Ng;Hedda Wardemann

  • B-cell tolerance checkpoints in health and autoimmunity.

    Eric Meffre;Hedda Wardemann

  • Cloning and expression of murine Ig genes from single B cells.

    Thomas Tiller;Christian E. Busse;Hedda Wardemann

  • B-1a B Cells that Link the Innate and Adaptive Immune Responses Are Lacking in the Absence of the Spleen

    Hedda Wardemann;Thomas Boehm;Neil Dear;Rita Carsetti

  • The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific

    Julia Benckert;Nina Schmolka;Cornelia Kreschel;Markus Josef Zoller

  • Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.

    Brun Mietzner;Makoto Tsuiji;Johannes Scheid;Klara Velinzon

  • Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.

    Jakob Kreye;Nina K. Wenke;Mariya Chayka;Jonas Leubner;Jonas Leubner

  • A checkpoint for autoreactivity in human IgM+ memory B cell development.

    Makoto Tsuiji;Sergey Yurasov;Sergey Yurasov;Klara Velinzon;Saskia Thomas

  • A method for identification of HIV gp140 binding memory B cells in human blood.

    Johannes F. Scheid;Hugo Mouquet;Niklas Feldhahn;Bruce D. Walker

  • B-cell self-tolerance in humans.

    Hedda Wardemann;Michel C. Nussenzweig

  • Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

    Khaled Amara;Johanna Steen;Fiona Murray;Henner Morbach

Frequent Co-Authors

Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Jean-Philippe Julien
Jean-Philippe Julien University of Toronto
Elena A. Levashina
Elena A. Levashina Max Planck Institute for Infection Biology
Hugo Mouquet
Hugo Mouquet Institut Pasteur
Michele Bombardieri
Michele Bombardieri Queen Mary University of London
Hassan Jumaa
Hassan Jumaa Max Planck Society
Jörg Köhl
Jörg Köhl University of Lübeck
Bruce D. Walker
Bruce D. Walker Harvard University
Benjamin Mordmüller
Benjamin Mordmüller Radboud University Medical Center
Virginia Pascual
Virginia Pascual Cornell University

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