2019 - Member of Academia Europaea
The scientist’s investigation covers issues in Antibody, Immunology, Antigen, Autoantibody and B cell. Antibody and Molecular biology are frequently intertwined in her study. Her work on Epitope is typically connected to Follicular dendritic cells as part of general Immunology study, connecting several disciplines of science.
Her Epitope study combines topics from a wide range of disciplines, such as Virus and Virology. Her Antigen research incorporates themes from breakpoint cluster region and DNA sequencing. The various areas that Hedda Wardemann examines in her B cell study include Antibody Diversity and Lymphocyte.
Hedda Wardemann mostly deals with Antibody, Immunology, Antigen, B cell and Monoclonal antibody. Her study in Antibody is interdisciplinary in nature, drawing from both Molecular biology and Virology. When carried out as part of a general Immunology research project, her work on Autoantibody, Immunoglobulin G, Autoimmunity and Somatic hypermutation is frequently linked to work in Naive B cell, therefore connecting diverse disciplines of study.
The Antigen study combines topics in areas such as T cell and Malaria vaccine. Her B cell research incorporates elements of Immunoglobulin M and Antibody Repertoire. Her Isotype study in the realm of Monoclonal antibody connects with subjects such as Population.
Hedda Wardemann mainly investigates Antibody, Antigen, Epitope, Plasmodium falciparum and Monoclonal antibody. Her work on Immunoglobulin G as part of general Antibody research is often related to Population, thus linking different fields of science. Her Antigen research entails a greater understanding of Immunology.
Hedda Wardemann focuses mostly in the field of Epitope, narrowing it down to matters related to Immune system and, in some cases, Lipopolysaccharide, Serotype and Microbiology. As a part of the same scientific family, Hedda Wardemann mostly works in the field of Plasmodium falciparum, focusing on Virology and, on occasion, Malaria. Her study in the field of Immunogen and Isotype also crosses realms of Inflammatory bowel disease and Glycan.
Epitope, Antibody, Antigen, Mucosal immunology and Serotype are her primary areas of study. Much of her study explores Antigen relationship to Mutation. The study incorporates disciplines such as Plasmodium falciparum, Circumsporozoite protein, Affinity maturation, Cell biology and Monoclonal antibody in addition to Mutation.
She has included themes like Lipopolysaccharide and Microbiology in her Mucosal immunology study.
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Predominant Autoantibody Production by Early Human B Cell Precursors
Hedda Wardemann;Sergey Yurasov;Sergey Yurasov;Anne Schaefer;James W. Young.
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
Thomas Tiller;Eric Meffre;Sergey Yurasov;Sergey Yurasov;Makoto Tsuiji.
Journal of Immunological Methods (2008)
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
Johannes F. Scheid;Hugo Mouquet;Niklas Feldhahn;Michael S. Seaman.
Visualizing dendritic cell networks in vivo.
Randall L Lindquist;Guy Shakhar;Diana Dudziak;Hedda Wardemann.
Nature Immunology (2004)
Defective B cell tolerance checkpoints in systemic lupus erythematosus
Sergey Yurasov;Hedda Wardemann;Johanna Hammersen;Makoto Tsuiji.
Journal of Experimental Medicine (2005)
The promise and challenge of high-throughput sequencing of the antibody repertoire.
George Georgiou;Gregory C Ippolito;John Beausang;Christian E Busse.
Nature Biotechnology (2014)
Autoreactivity in Human IgG+ Memory B Cells
Thomas Tiller;Makoto Tsuiji;Sergey Yurasov;Klara Velinzon.
Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
Marcus Dühren-von Minden;Rudolf Übelhart;Dunja Schneider;Thomas Wossning.
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
Hugo Mouquet;Johannes F. Scheid;Johannes F. Scheid;Markus J. Zoller;Michelle Krogsgaard.
Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity
Maxime Hervé;Kai Xu;Yen Shing Ng;Hedda Wardemann.
Journal of Clinical Investigation (2005)
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