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Molecular Biology

D-Index
44
Citations
9930
World Ranking
2903
National Ranking
1386

Overview

Gary LeRoy is affiliated with New York University in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Genetics, and Plant Science at the subfield level.

Their work covers several main topics including:

  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Chromatin Remodeling and Cancer
  • Epigenetics and DNA Methylation
  • CRISPR and Genetic Engineering

LeRoy has authored papers in high-profile journals and has a notable presence in several publication venues. Frequent publication outlets include:

  • Molecular Cell
  • Cell
  • Nature
  • Nature Genetics
  • Science Advances

Selected recent papers with publication year and venue are:

  • RNA-Mediated Feedback Control of Transcriptional Condensates, 2020, Cell
  • MeCP2 links heterochromatin condensates and neurodevelopmental disease, 2020, Nature
  • CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters, 2022, Nature Genetics
  • The H3K36me2 writer-reader dependency in H3K27M-DIPG, 2021, Science Advances
  • An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions, 2021, Frontiers in Cell and Developmental Biology

Frequent co-authors in LeRoy's research include:

  • Danny Reinberg
  • Jonathan E. Henninger
  • Ozgur Oksuz
  • Alicia V. Zamudio
  • Nancy M. Hannett

Best Publications

  • The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.

    Yi Zhang;Gary LeRoy;Hans-Peter Seelig;William S Lane

  • FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes

    George Orphanides;Gary LeRoy;Chun Hsiang Chang;Donal S. Luse

  • RNA-Mediated Feedback Control of Transcriptional Condensates.

    Jonathan E. Henninger;Ozgur Oksuz;Krishna Shrinivas;Krishna Shrinivas;Ido Sagi

  • Asymmetrically Modified Nucleosomes

    Philipp Voigt;Gary LeRoy;William J. Drury;Barry M. Zee

  • The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription

    Gary LeRoy;Brenden Rickards;S.J. Flint

  • Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.

    Taro Hitosugi;Lu Zhou;Shannon Elf;Jun Fan

  • Requirement of RSF and FACT for Transcription of Chromatin Templates in Vitro

    Gary LeRoy;George Orphanides;William S. Lane;Danny Reinberg

  • BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

    Tomohiko Kanno;Yuka Kanno;Gary Leroy;Eric Campos

  • In Vivo Residue-specific Histone Methylation Dynamics

    Barry M. Zee;Rebecca S. Levin;Bo Xu;Gary LeRoy

  • Capturing the Onset of PRC2-Mediated Repressive Domain Formation.

    Ozgur Oksuz;Varun Narendra;Chul Hwan Lee;Nicolas Descostes

  • MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency

    Alexandre Gaspar-Maia;Zulekha A. Qadeer;Dan Hasson;Kajan Ratnakumar

  • Purification and Characterization of a Human Factor That Assembles and Remodels Chromatin

    Gary LeRoy;Alejandra Loyola;William S. Lane;Danny Reinberg

  • Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma

    James M. Stafford;Chul Hwan Lee;Philipp Voigt;Nicolas Descostes

  • MeCP2 links heterochromatin condensates and neurodevelopmental disease

    Charles H. Li;Eliot L. Coffey;Alessandra Dall’Agnese;Nancy M. Hannett

  • One-pot shotgun quantitative mass spectrometry characterization of histones.

    Mariana D. Plazas-Mayorca;Barry M. Zee;Nicolas L. Young;Ian M. Fingerman

  • Nucleolin Is Required for RNA Polymerase I Transcription In Vivo

    Brenden Rickards;S. J. Flint;Michael D. Cole;Gary LeRoy

  • ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

    Kajan Ratnakumar;Luis F. Duarte;Gary LeRoy;Dan Hasson

  • A quantitative atlas of histone modification signatures from human cancer cells

    Gary LeRoy;Peter A DiMaggio;Eric Y Chan;Barry M Zee

  • Global secretome analysis identifies novel mediators of bone metastasis

    Mario Andres Blanco;Gary LeRoy;Zia Khan;Zia Khan;Maša Alečković

  • Functional analysis of the subunits of the chromatin assembly factor RSF.

    Alejandra Loyola;Jing-Yi Huang;Gary LeRoy;Gary LeRoy;Sherrie Hu;Sherrie Hu

Frequent Co-Authors

Danny Reinberg
Danny Reinberg University of Miami
Benjamin A. Garcia
Benjamin A. Garcia Washington University in St. Louis
Yibin Kang
Yibin Kang Princeton University
Ihor R. Lemischka
Ihor R. Lemischka Icahn School of Medicine at Mount Sinai
William S. Lane
William S. Lane Harvard University
Jane A. Skok
Jane A. Skok New York University
Beatrix Ueberheide
Beatrix Ueberheide New York University
S. J. Flint
S. J. Flint Princeton University
Peng Jin
Peng Jin Emory University
Stephen J. Elledge
Stephen J. Elledge Harvard University

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