World's Best Scientists 2026 revealed!
Akio Toh-e

Akio Toh-e

D-Index & Metrics

Molecular Biology

D-Index
74
Citations
14332
World Ranking
1252
National Ranking
102

Overview

Akio Toh-e is a researcher affiliated with Chiba University in Japan with a primary focus in the field of Medicine. Their research spans several subfields, including Epidemiology, Plant Science, Infectious Diseases, Oncology, and Endocrinology. The investigator's work centers on fungal infections and studies, with additional interests in antifungal resistance and susceptibility, peptidase inhibition and analysis, plant and fungal interactions, plant disease resistance and genetics, polyamine metabolism, and Pneumocystis jirovecii pneumonia detection and treatment.

Among the recent publications by Akio Toh-e are the following papers:

  • "Step-wise elimination of α-mitochondrial nucleoids and mitochondrial structure as a basis for the strict uniparental inheritance in Cryptococcus neoformans" (2020, Scientific Reports)
  • "Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans" (2023, mBio)
  • "Identification and characterization of a sulfite reductase gene and new insights regarding the sulfur-containing amino acid metabolism in the basidiomycetous yeast Cryptococcus neoformans" (2020, Current Genetics)
  • "Genetic system underlying responses of Cryptococcus neoformans to cadmium" (2021, Current Genetics)
  • "Vph1 is associated with the copper homeostasis of Cryptococcus neoformans serotype D" (2021, The Journal of General and Applied Microbiology)

Akio Toh-e collaborates with fellow researchers in their investigations. Frequent co-authors include Akira Watanabe, Katsuhiko Kamei, Yoshiki Nishimura, Toshiharu Shikanai, and Susumu Kawamoto. Work by Toh-e commonly appears in journals such as Current Genetics, Scientific Reports, mBio, and The Journal of General and Applied Microbiology.

The scientific contributions of Akio Toh-e focus largely on fungal biology, particularly on Cryptococcus neoformans, a pathogenic yeast species. Their research explores mechanisms of fungal inheritance, signaling pathways affecting metabolism and virulence, sulfur-containing amino acid metabolism, heavy metal response mechanisms, and metal ion homeostasis in fungal cells.

Best Publications

  • Expression of hepatitis B surface antigen gene in yeast

    Atsushi Miyanohara;Akio Toh-E;Chikateru Nozaki;Fukusaburo Hamada

  • S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein

    Kazuma Tanaka;Masato Nakafuku;Takaya Satoh;Mark S. Marshall

  • Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae.

    Akio Toh-e;Yoshinami Ueda;Sei-Ichiro Kakimoto;Yasuji Oshima

  • Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

    Yasushi Saeki;Tai Kudo;Takayuki Sone;Yoshiko Kikuchi

  • Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

    Fumio Osaka;Mihoro Saeki;Satoshi Katayama;Noriko Aida

  • Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70.

    Nicole G. G. Robinson;Lea Guo;Jun Imai;Akio Toh-e

  • Yeast Ull1/Siz1 Is a Novel SUMO1/Smt3 Ligase for Septin Components and Functions as an Adaptor between Conjugating Enzyme and Substrates

    Yoshimitsu Takahashi;Tomoaki Kahyo;Akio Toh-e;Hideyo Yasuda

  • Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle.

    Yasushi Saeki;Akio Toh-e;Tai Kudo;Hitomi Kawamura

  • 26S proteasome regulatory particle mutants have increased oxidative stress tolerance.

    Jasmina Kurepa;Akio Toh-e;Jan A. Smalle

  • Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1.

    Y Matsui;A Toh-E

  • Transient Inhibition of Translation Initiation by Osmotic Stress

    Yukifumi Uesono;Akio Toh-e

  • Ubiquitin-like proteins and Rpn10 play cooperative roles in ubiquitin-dependent proteolysis.

    Yasushi Saeki;Aki Saitoh;Akio Toh-e;Hideyoshi Yokosawa

  • Identification of ubiquitin-like protein-binding subunits of the 26S proteasome.

    Yasushi Saeki;Takayuki Sone;Akio Toh-e;Hideyoshi Yokosawa

  • Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae.

    Takashi Itoh;Akiko Watabe;Akio Toh-e;Yasushi Matsui

  • PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae.

    Akio Toh-e;Kazuma Tanaka;Yukifumi Uesono;Reed B. Wickner

  • Sem1p Is a Novel Subunit of the 26 S Proteasome from Saccharomyces cerevisiae

    Takayuki Sone;Yasushi Saeki;Yasushi Saeki;Akio Toh-e;Hideyoshi Yokosawa

  • CDC33 encodes mRNA cap-binding protein eIF-4E of Saccharomyces cerevisiae.

    C. Brenner;Naoki Nakayama;M. Goebl;K. Tanaka

  • Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle

    Daniel Finley;Keiji Tanaka;Carl Mann;Horst Feldmann

  • Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity.

    Yasushi Saeki;Erika Isono;Akio Toh‐e

  • Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast

    Takashi Itoh;Akio Toh-e;Yasushi Matsui

Frequent Co-Authors

Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Kenichi Matsubara
Kenichi Matsubara Osaka University
Yasuji Oshima
Yasuji Oshima Osaka University
Hideyoshi Yokosawa
Hideyoshi Yokosawa Hokkaido University
Yoshito Kaziro
Yoshito Kaziro Kyoto University
Masato Nakafuku
Masato Nakafuku Cincinnati Children's Hospital Medical Center
Ichiro Terashima
Ichiro Terashima National Chung Hsing University
Tomoyoshi Nozaki
Tomoyoshi Nozaki University of Tokyo
Ko Noguchi
Ko Noguchi Tokyo University of Pharmacy and Life Sciences
Katsuhiko Shirahige
Katsuhiko Shirahige University of Tokyo

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students interested in Molecular Biology may also explore alternative or complementary health science careers, many of which can be pursued through flexible online programs. For example, those looking for rapid entry into nursing can consider online accelerated bsn programs for non nurses, which offer a fast track to becoming a registered nurse even for those without prior nursing experience.

Existing nurses aiming to advance their credentials may benefit from accelerated bsn programs that can be completed in as little as six months. For those considering future specialization, understanding career outcomes is essential. For instance, nurse practitioners specializing in mental health will want to know the current dnp pmhnp salary data to plan their education investment accordingly.

If speed to practice is important, learning how long does it take to be a nurse practitioner can help in making informed decisions about various educational pathways. Together, these options provide a flexible foundation for a wide range of bioscience and health careers linked to Molecular Biology.

Best Scientists Citing Akio Toh-e

Trending Scientists

Recently Published Articles